Page last updated: 2024-10-20

taurine and Bipolar Disorder

taurine has been researched along with Bipolar Disorder in 10 studies

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Data were collected during an 8-week randomized controlled trial of acamprosate for individuals with co-occurring bipolar disorder and alcohol dependence (n = 30)."9.16Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate. ( Brady, KT; Brown, DG; Chiuzan, C; DeSantis, SM; Prisciandaro, JJ; Tolliver, BK, 2012)
"Acamprosate was well-tolerated, with no worsening of depressive or manic symptoms, and appeared to confer some clinical benefit in study completers in the last two weeks of the trial."6.77A randomized, double-blind, placebo-controlled clinical trial of acamprosate in alcohol-dependent individuals with bipolar disorder: a preliminary report. ( Brady, KT; Brown, DG; Desantis, SM; Prisciandaro, JJ; Tolliver, BK, 2012)
"Data were collected during an 8-week randomized controlled trial of acamprosate for individuals with co-occurring bipolar disorder and alcohol dependence (n = 30)."5.16Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate. ( Brady, KT; Brown, DG; Chiuzan, C; DeSantis, SM; Prisciandaro, JJ; Tolliver, BK, 2012)
"Acamprosate was well-tolerated, with no worsening of depressive or manic symptoms, and appeared to confer some clinical benefit in study completers in the last two weeks of the trial."2.77A randomized, double-blind, placebo-controlled clinical trial of acamprosate in alcohol-dependent individuals with bipolar disorder: a preliminary report. ( Brady, KT; Brown, DG; Desantis, SM; Prisciandaro, JJ; Tolliver, BK, 2012)
"Comorbidity of alcohol abuse and dependence with bipolar disorders is high."1.38Commentary on the study: impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate (Prisciandaro et al.). ( Preuss, UW, 2012)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Geoffroy, PA1
Gottlieb, J1
Wu, TN1
Chen, CK1
Lee, CS1
Wu, BJ1
Sun, HJ1
Chang, CH1
Chen, CY1
Wu, LS1
Cheng, AT1
Icro Maremmani, AG1
Bacciardi, S1
Rovai, L1
Rugani, F1
Massimetti, E1
Gazzarrini, D1
Dell'Osso, L1
Maremmani, I1
Prisciandaro, JJ3
Brown, DG3
Brady, KT3
Tolliver, BK3
DeSantis, SM2
Chiuzan, C1
Preuss, UW1
Fekkes, D2
Pepplinkhuizen, L2
Verheij, R1
Bruinvels, J2
Machado-Vieira, R1
Viale, CI1
Kapczinski, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776]Phase 254 participants (Actual)Interventional2017-08-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Prefrontal GABA+ Concentrations

Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine3.90
Gabapentin3.93
Placebo Oral Tablet3.73

Prefrontal Glx Concentrations

Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine21.59
Gabapentin21.69
Placebo Oral Tablet22.25

Trials

3 trials available for taurine and Bipolar Disorder

ArticleYear
Comorbid anxiety disorders and baseline medication regimens predict clinical outcomes in individuals with co-occurring bipolar disorder and alcohol dependence: Results of a randomized controlled trial.
    Psychiatry research, 2011, Aug-15, Volume: 188, Issue:3

    Topics: Acamprosate; Adult; Alcohol Deterrents; Alcoholism; Anxiety Disorders; Bipolar Disorder; Comorbidity

2011
Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate.
    Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:3

    Topics: Acamprosate; Adolescent; Adult; Aged; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Behavior, Ad

2012
A randomized, double-blind, placebo-controlled clinical trial of acamprosate in alcohol-dependent individuals with bipolar disorder: a preliminary report.
    Bipolar disorders, 2012, Volume: 14, Issue:1

    Topics: Acamprosate; Adult; Affect; Alcohol Deterrents; Alcoholism; Bipolar Disorder; Double-Blind Method; F

2012

Other Studies

7 other studies available for taurine and Bipolar Disorder

ArticleYear
Activity, cognition, and emotion: Three dimensional pillars of the natural presentations of mood disorders enriched by the "sleep" fourth dimension (ACES).
    Bipolar disorders, 2020, Volume: 22, Issue:6

    Topics: Bipolar Disorder; Cognition; Emotions; Humans; Mood Disorders; Sleep; Taurine

2020
Lithium and GADL1 regulate glycogen synthase kinase-3 activity to modulate KCTD12 expression.
    Scientific reports, 2019, 07-16, Volume: 9, Issue:1

    Topics: Asian People; Bipolar Disorder; Carboxy-Lyases; Case-Control Studies; Cell Line, Tumor; gamma-Aminob

2019
Six-month outcome in bipolar spectrum alcoholics treated with acamprosate after detoxification: a retrospective study.
    International journal of environmental research and public health, 2014, Volume: 11, Issue:12

    Topics: Acamprosate; Adolescent; Adult; Aged; Alcohol Deterrents; Alcoholism; Bipolar Disorder; Female; Huma

2014
Commentary on the study: impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate (Prisciandaro et al.).
    Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:6

    Topics: Alcohol Drinking; Alcoholism; Behavior, Addictive; Bipolar Disorder; Depression; Female; Humans; Mal

2012
Abnormal plasma levels of serine, methionine, and taurine in transient acute polymorphic psychosis.
    Psychiatry research, 1994, Volume: 51, Issue:1

    Topics: Adult; Bipolar Disorder; Diagnosis, Differential; Female; Humans; Male; Methionine; Middle Aged; Psy

1994
Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001, Volume: 46, Issue:5

    Topics: Adult; Bipolar Disorder; Caffeine; Humans; Inositol; Male; Taurine

2001
Derangement of one-carbon metabolism in episodic schizoaffective psychoses.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:1

    Topics: Bipolar Disorder; Carbolines; Carbon; Glycine; Humans; Schizophrenia; Serine; Taurine

1988