taurine has been researched along with Bile Duct Obstruction in 42 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ursodeoxycholic acid (UDCA) exerts anticholestatic, antifibrotic and antiproliferative effects in primary biliary cirrhosis (PBC) via mechanisms not yet fully understood." | 9.16 | Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health. ( Bastiaansen, BA; Beuers, U; Dilger, K; Hohenester, S; Rust, C; Schaap, FG; Winkler-Budenhofer, U, 2012) |
| "NorUDCA (24-norursodeoxycholic acid), the C₂₃-homolog of ursodeoxycholic acid (UDCA), showed remarkable therapeutic effects in cholestatic Mdr2 (Abcb4) (multidrug resistance protein 2/ATP-binding cassette b4) knockout mice with sclerosing/fibrosing cholangitis." | 7.76 | Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver. ( Beuers, U; Denk, GU; Ferdinandusse, S; Fickert, P; Fuchsbichler, A; Hofmann, AF; Invernizzi, P; Kulik, W; Maitz, S; Rust, C; Trauner, M; Wimmer, R, 2010) |
| "Taurine seems to be essential in the newborn for bile acid (BA) tauroconjugation, and its deficiency has been implicated in total parenteral nutrition-associated cholestasis (TPN-AC)." | 7.73 | Taurine and cholestasis associated to TPN. Experimental study in rabbit model. ( Botello, F; Climent, V; Macià, E; Moran, JM; Salas, J, 2005) |
| "The effect of oral taurine supplementation on endotoxin-induced cholestasis was investigated in rat liver." | 7.72 | Taurine supplementation induces multidrug resistance protein 2 and bile salt export pump expression in rats and prevents endotoxin-induced cholestasis. ( Dransfeld, O; Häussinger, D; Kubitz, R; Mühlfeld, A; Wettstein, M, 2003) |
| "We investigated the effects of tauroursodeoxycholate (UR-906) and ursodeoxycholic acid (UDCA) on alpha-naphthylisothiocyanate (ANIT)-induced cholestasis in mice." | 7.68 | Protection against alpha-naphthylisothiocyanate-induced acute cholestasis in mice by a novel taurine conjugate of ursodeoxycholate (UR-906). ( Araki, T; Ishizaki, K; Kinbara, S; Miyazawa, N; Takeuchi, Y, 1993) |
| "To review the evidence that taurine can prevent cholestasis in neonates." | 7.68 | Taurine: an essential amino acid to prevent cholestasis in neonates? ( Howard, D; Thompson, DF, 1992) |
| " After colchicine treatment, taurocholic acid (TCA) administration was associated with marked cholestasis while both beta-MCA and T beta-MCA still increased bile flow under the same conditions." | 7.68 | Tauro-beta-muricholate preserves choleresis and prevents taurocholate-induced cholestasis in colchicine-treated rat liver. ( Hayakawa, T; Hoshino, M; Katagiri, K; Miyaji, M; Nakai, T; Ohiwa, T; Ohnishi, H; Okayama, Y; Takeuchi, T; Yamada, T, 1992) |
| " Coadministration of RES and LUT could significantly improve the bioavailability of LUT and increase the systemic exposure to RES, and the combined treatment could also benefit from their multi-component and multi-target characteristics." | 5.72 | Combination of resveratrol and luteolin ameliorates α-naphthylisothiocyanate-induced cholestasis by regulating the bile acid homeostasis and suppressing oxidative stress. ( Li, K; Ran, X; Wang, W; Wei, X; Wu, W; Xu, X; Zhang, T; Zhang, Y, 2022) |
| "Taurine (TAU) is an abundant amino acid with substantial anti-inflammatory and antioxidative properties." | 5.72 | Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation. ( Abdoli, N; Azarpira, N; Heidari, R; Lu, Y; Ma, Y; Manthari, RK; Mazloomi, S; Mehrabani, PS; Mingyu, Y; Mobasheri, A; Mousavifaraz, A; Nadgaran, A; Niknahad, H; Nikoozadeh, A; Ommati, MM; Rezaei, M; Sadeghian, I; Tang, Z; Xin, H; Xu, D, 2022) |
| "Ursodeoxycholic acid (UDCA) exerts anticholestatic, antifibrotic and antiproliferative effects in primary biliary cirrhosis (PBC) via mechanisms not yet fully understood." | 5.16 | Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health. ( Bastiaansen, BA; Beuers, U; Dilger, K; Hohenester, S; Rust, C; Schaap, FG; Winkler-Budenhofer, U, 2012) |
| "To evaluate the potential role of taurine deficiency in the pathogenesis of parenteral nutrition-induced cholestasis, 20 premature (less than 34 weeks AGA) infants were randomized to receive parenteral nutrition with and without taurine (10." | 5.05 | Effect of taurine supplementation on hepatic function during short-term parenteral nutrition in the premature infant. ( Cooke, RJ; Kelts, D; Whitington, PF, 1984) |
| "NorUDCA (24-norursodeoxycholic acid), the C₂₃-homolog of ursodeoxycholic acid (UDCA), showed remarkable therapeutic effects in cholestatic Mdr2 (Abcb4) (multidrug resistance protein 2/ATP-binding cassette b4) knockout mice with sclerosing/fibrosing cholangitis." | 3.76 | Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver. ( Beuers, U; Denk, GU; Ferdinandusse, S; Fickert, P; Fuchsbichler, A; Hofmann, AF; Invernizzi, P; Kulik, W; Maitz, S; Rust, C; Trauner, M; Wimmer, R, 2010) |
| "Taurine seems to be essential in the newborn for bile acid (BA) tauroconjugation, and its deficiency has been implicated in total parenteral nutrition-associated cholestasis (TPN-AC)." | 3.73 | Taurine and cholestasis associated to TPN. Experimental study in rabbit model. ( Botello, F; Climent, V; Macià, E; Moran, JM; Salas, J, 2005) |
| "The effect of oral taurine supplementation on endotoxin-induced cholestasis was investigated in rat liver." | 3.72 | Taurine supplementation induces multidrug resistance protein 2 and bile salt export pump expression in rats and prevents endotoxin-induced cholestasis. ( Dransfeld, O; Häussinger, D; Kubitz, R; Mühlfeld, A; Wettstein, M, 2003) |
| " Ursodeoxycholic acid (UDC), a nonhepatotoxic bile acid, has proved to be efficient for several types of cholestasis." | 3.68 | Diminution of an acute cyclosporin-induced cholestasis by tauroursodeoxycholate in the rat. ( Bertault-Perès, P; Durand, A; Mesdjian, E; Montet, JC; Queneau, PE, 1993) |
| "We investigated the effects of tauroursodeoxycholate (UR-906) and ursodeoxycholic acid (UDCA) on alpha-naphthylisothiocyanate (ANIT)-induced cholestasis in mice." | 3.68 | Protection against alpha-naphthylisothiocyanate-induced acute cholestasis in mice by a novel taurine conjugate of ursodeoxycholate (UR-906). ( Araki, T; Ishizaki, K; Kinbara, S; Miyazawa, N; Takeuchi, Y, 1993) |
| "To review the evidence that taurine can prevent cholestasis in neonates." | 3.68 | Taurine: an essential amino acid to prevent cholestasis in neonates? ( Howard, D; Thompson, DF, 1992) |
| " After colchicine treatment, taurocholic acid (TCA) administration was associated with marked cholestasis while both beta-MCA and T beta-MCA still increased bile flow under the same conditions." | 3.68 | Tauro-beta-muricholate preserves choleresis and prevents taurocholate-induced cholestasis in colchicine-treated rat liver. ( Hayakawa, T; Hoshino, M; Katagiri, K; Miyaji, M; Nakai, T; Ohiwa, T; Ohnishi, H; Okayama, Y; Takeuchi, T; Yamada, T, 1992) |
| "The present study was aimed at determining whether the protection by taurine of lithocholate-sulfate-induced cholestasis is mediated by conjugation or by direct effect of the amino acid on bile formation." | 3.68 | The effect of taurine on the cholestatic potential of sulfated lithocholate and its conjugates. ( Belli, DC; Fournier, LA; Giguère, R; Roy, CC; Tuchweber, B; Yousef, IM, 1991) |
| "The etiology of the severe hepatic dysfunction associated with total parenteral nutrition (TPN) remains unknown, but recent studies suggest that taurine deficiency may be associated with the development of cholestasis in experimental animals." | 3.67 | Taurine deficiency in the severe hepatic dysfunction complicating total parenteral nutrition. ( Betts, JM; Cooper, A; Pereira, GR; Ziegler, MM, 1984) |
| " In contrast to the expected 30% to 50% incidence of cholestasis, only one of these 31 experienced an unexplained increase in serum total bilirubin concentration during study, suggesting that normalizing plasma amino acid concentrations and/or providing taurine during parenteral nutrition may decrease the incidence of cholestasis associated with this therapy." | 3.67 | Amino acid mixture designed to maintain normal plasma amino acid patterns in infants and children requiring parenteral nutrition. ( Ament, ME; Dell, RB; Greene, HL; Heird, WC; Helms, RA; Karna, P; Storm, MC, 1987) |
| " Coadministration of RES and LUT could significantly improve the bioavailability of LUT and increase the systemic exposure to RES, and the combined treatment could also benefit from their multi-component and multi-target characteristics." | 1.72 | Combination of resveratrol and luteolin ameliorates α-naphthylisothiocyanate-induced cholestasis by regulating the bile acid homeostasis and suppressing oxidative stress. ( Li, K; Ran, X; Wang, W; Wei, X; Wu, W; Xu, X; Zhang, T; Zhang, Y, 2022) |
| "Taurine (TAU) is an abundant amino acid with substantial anti-inflammatory and antioxidative properties." | 1.72 | Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation. ( Abdoli, N; Azarpira, N; Heidari, R; Lu, Y; Ma, Y; Manthari, RK; Mazloomi, S; Mehrabani, PS; Mingyu, Y; Mobasheri, A; Mousavifaraz, A; Nadgaran, A; Niknahad, H; Nikoozadeh, A; Ommati, MM; Rezaei, M; Sadeghian, I; Tang, Z; Xin, H; Xu, D, 2022) |
| "Patients with biliary atresia (i." | 1.38 | Intestinal synthesis and secretion of bile salts as an adaptation to developmental biliary atresia in the sea lamprey. ( Chung-Davidson, YW; Li, K; Li, W; Wang, H; Yeh, CY, 2012) |
| "Glycine/taurine was greater in group II versus III and varied directly with serum bile acid concentration." | 1.28 | Altered glycine and taurine conjugation of bile acids following aluminum administration to rats. ( Heyman, MB; Klein, GL; Lee, TC; Rassin, DK, 1989) |
| "A significant dose-response correlation was found between taurolithocholate and the degree of cholestasis." | 1.25 | Cholestasis induced by sodium taurolithocholate in isolated hamster liver. ( King, JE; Schoenfield, LJ, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (45.24) | 18.7374 |
| 1990's | 10 (23.81) | 18.2507 |
| 2000's | 5 (11.90) | 29.6817 |
| 2010's | 6 (14.29) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, W | 1 |
| Li, K | 2 |
| Ran, X | 1 |
| Wang, W | 1 |
| Xu, X | 1 |
| Zhang, Y | 1 |
| Wei, X | 1 |
| Zhang, T | 1 |
| Ommati, MM | 1 |
| Mobasheri, A | 1 |
| Ma, Y | 1 |
| Xu, D | 2 |
| Tang, Z | 1 |
| Manthari, RK | 1 |
| Abdoli, N | 1 |
| Azarpira, N | 1 |
| Lu, Y | 1 |
| Sadeghian, I | 1 |
| Mousavifaraz, A | 1 |
| Nadgaran, A | 1 |
| Nikoozadeh, A | 1 |
| Mazloomi, S | 1 |
| Mehrabani, PS | 1 |
| Rezaei, M | 1 |
| Xin, H | 1 |
| Mingyu, Y | 1 |
| Niknahad, H | 1 |
| Heidari, R | 1 |
| Anaya-Flórez, MS | 1 |
| Barbosa-Cortés, L | 1 |
| Villasis-Keever, MA | 1 |
| Aguilar-Monroy, S | 1 |
| Montalvo-Velarde, I | 1 |
| López-Alarcón, M | 1 |
| Lledias-Corona, M | 1 |
| Huerta-Tecanhuey, A | 1 |
| Maldonado-Hernández, J | 1 |
| Madrigal-Muñiz, O | 1 |
| González-Cabello, H | 1 |
| Schacht, AC | 1 |
| Sørensen, M | 1 |
| Munk, OL | 1 |
| Frisch, K | 1 |
| Wang, Y | 1 |
| Mei, X | 1 |
| Yuan, J | 1 |
| Lai, X | 1 |
| Denk, GU | 1 |
| Maitz, S | 1 |
| Wimmer, R | 1 |
| Rust, C | 2 |
| Invernizzi, P | 1 |
| Ferdinandusse, S | 1 |
| Kulik, W | 1 |
| Fuchsbichler, A | 1 |
| Fickert, P | 1 |
| Trauner, M | 1 |
| Hofmann, AF | 1 |
| Beuers, U | 2 |
| Dilger, K | 1 |
| Hohenester, S | 1 |
| Winkler-Budenhofer, U | 1 |
| Bastiaansen, BA | 1 |
| Schaap, FG | 1 |
| Yeh, CY | 1 |
| Chung-Davidson, YW | 1 |
| Wang, H | 1 |
| Li, W | 1 |
| Mühlfeld, A | 1 |
| Kubitz, R | 1 |
| Dransfeld, O | 1 |
| Häussinger, D | 1 |
| Wettstein, M | 1 |
| Liu, Y | 1 |
| Binz, J | 1 |
| Numerick, MJ | 1 |
| Dennis, S | 1 |
| Luo, G | 1 |
| Desai, B | 1 |
| MacKenzie, KI | 1 |
| Mansfield, TA | 1 |
| Kliewer, SA | 1 |
| Goodwin, B | 1 |
| Jones, SA | 1 |
| Moran, JM | 1 |
| Salas, J | 1 |
| Botello, F | 1 |
| Macià, E | 1 |
| Climent, V | 1 |
| Linnet, K | 1 |
| Andersen, JR | 1 |
| Hoshita, T | 1 |
| Yamanaka, M | 1 |
| Sano, N | 1 |
| Itokazu, K | 1 |
| Yokote, M | 1 |
| Cooke, RJ | 1 |
| Whitington, PF | 1 |
| Kelts, D | 1 |
| Cooper, A | 1 |
| Betts, JM | 1 |
| Pereira, GR | 1 |
| Ziegler, MM | 1 |
| Miyazaki, S | 1 |
| Tanaka, H | 1 |
| Horikawa, R | 1 |
| Tsuchiya, H | 1 |
| Imai, K | 1 |
| Queneau, PE | 1 |
| Bertault-Perès, P | 1 |
| Mesdjian, E | 1 |
| Durand, A | 1 |
| Montet, JC | 1 |
| Kinbara, S | 1 |
| Ishizaki, K | 1 |
| Takeuchi, Y | 1 |
| Miyazawa, N | 1 |
| Araki, T | 1 |
| Donovan, JM | 1 |
| Yousef, IM | 2 |
| Carey, MC | 1 |
| Baumgartner, U | 1 |
| Schölmerich, J | 1 |
| Sellinger, M | 1 |
| Reinhardt, M | 1 |
| Ruf, G | 1 |
| Farthmann, EH | 1 |
| Meehan, JJ | 1 |
| Georgeson, KE | 1 |
| Kerai, MD | 1 |
| Waterfield, CJ | 1 |
| Kenyon, SH | 1 |
| Asker, DS | 1 |
| Timbrell, JA | 1 |
| Rolo, AP | 1 |
| Oliveira, PJ | 1 |
| Moreno, AJ | 1 |
| Palmeira, CM | 1 |
| Btaiche, IF | 1 |
| Khalidi, N | 1 |
| Watkins, JB | 1 |
| Perman, JA | 1 |
| Hardison, WG | 1 |
| Danielsson, H | 1 |
| Sjövall, J | 1 |
| Howard, D | 1 |
| Thompson, DF | 1 |
| Katagiri, K | 1 |
| Nakai, T | 1 |
| Hoshino, M | 1 |
| Hayakawa, T | 1 |
| Ohnishi, H | 1 |
| Okayama, Y | 1 |
| Yamada, T | 1 |
| Ohiwa, T | 1 |
| Miyaji, M | 1 |
| Takeuchi, T | 1 |
| Belli, DC | 1 |
| Roy, CC | 1 |
| Fournier, LA | 1 |
| Tuchweber, B | 1 |
| Giguère, R | 1 |
| Riely, CA | 1 |
| Klein, GL | 1 |
| Lee, TC | 1 |
| Heyman, MB | 1 |
| Rassin, DK | 1 |
| Heird, WC | 1 |
| Dell, RB | 1 |
| Helms, RA | 1 |
| Greene, HL | 1 |
| Ament, ME | 1 |
| Karna, P | 1 |
| Storm, MC | 1 |
| Doumas, BT | 1 |
| Perry, B | 1 |
| Jendrzejczak, B | 1 |
| Davis, L | 1 |
| Scherstén, T | 1 |
| Stremmel, W | 1 |
| Murphy, GM | 1 |
| Ross, A | 1 |
| Billing, BH | 1 |
| King, JE | 1 |
| Schoenfield, LJ | 1 |
| Priestly, BG | 1 |
| Côté, MG | 1 |
| Plaa, GL | 1 |
| Neale, G | 1 |
| Lewis, B | 1 |
| Weaver, V | 1 |
| Panveliwalla, D | 1 |
| Javitt, NB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00529009] | Phase 1 | 0 participants | Interventional | 2007-05-31 | Completed | ||
| Expanded Access Use of Omegaven® in the Treatment of Parenteral Nutrition Induced Liver Injury in Children[NCT02925520] | 0 participants | Expanded Access | No longer available | ||||
| Compassionate Use of an Intravenous Fat Emulsion Comprised of Fish Oil in the Treatment of Parenteral Nutrition Induced Liver Injury in Infants[NCT00738101] | 293 participants (Actual) | Interventional | 2008-09-30 | Completed | |||
| Research Study of an Intravenous Fat Emulsion Comprised of Fish Oils (Omegaven) in the Treatment of Parenteral Nutrition (PN) Induced Liver Injury[NCT01089426] | 90 participants (Actual) | Interventional | 2008-09-30 | Completed | |||
| Calciuric Effect and Cyclic Parenteral Nutrition in Preterm Infants[NCT00711763] | 1 participants (Actual) | Observational | 2008-07-31 | Terminated (stopped due to failure to recruit more patients and lack of supporting personnel.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
To describe proportion of infants who died secondary to any cause, related or unrelated to Fish Oil Emulsion. (NCT00738101)
Timeframe: From initiation to end of study (End of Study : Discontinuation of Fish Oil Emulsion, Death, Transplant, or Discharge from the hospital, whichever is achieved first, up to 5 years).
| Intervention | Participants (Count of Participants) |
|---|---|
| Fish Oil Emulsion Arm | 30 |
To describe number and percentage of infants who died secondary to any cause, related or unrelated to Fish Oil Emulsion. (NCT00738101)
Timeframe: Anytime from initiation of study to discharge from the hospital.
| Intervention | Participants (Count of Participants) |
|---|---|
| Fish Oil Emulsion Arm | 40 |
The Z-score indicated the number of standard deviations away from the mean. A weight Z-score of 0 is equal to the mean. A weight Z-score of ≤ -2 indicates an underweight status, while a weight Z-score of ≥ 2 indicates overweight or obese status. (NCT00738101)
Timeframe: From initiation to end of study (End of Study : Discontinuation of Fish Oil Emulsion, Death, Transplant, or Discharge from the hospital, whichever is achieved first, up to 5 years).
| Intervention | z-score (Mean) |
|---|---|
| Fish Oil Emulsion Arm | -1.48 |
To describe the number and percentage of infants who required liver or multi-visceral transplant. (NCT00738101)
Timeframe: From initiation to end of study (End of Study : Discontinuation of Fish Oil Emulsion, Death, Transplant, or Discharge from the hospital, whichever is achieved first, up to 5 years).
| Intervention | Participants (Count of Participants) |
|---|---|
| Fish Oil Emulsion Arm | 2 |
Time in days from the initiation of fish oil emulsions (initiation of study) until resolution of cholestasis as defined by serum conjugated bilirubin≤ 2 mg/dL prior to EOS (end of study). (NCT00738101)
Timeframe: From initiation to end of study (End of Study : Discontinuation of Fish Oil Emulsion, Death, Transplant, or Discharge from the hospital, whichever is achieved first, up to 5 years).
| Intervention | Days (Mean) |
|---|---|
| Fish Oil Emulsion Arm | 38.02 |
5 reviews available for taurine and Bile Duct Obstruction
| Article | Year |
|---|---|
[Conjugation and deconjugation of bile acids].
Topics: Bile Acids and Salts; Cholestasis; Glucuronates; Glycine; Humans; Liver; Sulfuric Acids; Taurine | 1984 |
[Abnormal bile acids in obstructive jaundice].
Topics: Animals; Bile Acids and Salts; Cholestasis; Cholic Acid; Cholic Acids; Glycine; Humans; Rats; Taurin | 1984 |
Parenteral nutrition-associated liver complications in children.
Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Bilirubin; Carnitine; Child; Cholestasis; gamma-Glutamy | 2002 |
Bile acid metabolism in infants and children.
Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cystic Fibrosis; Diarrhea; Digestive Syste | 1977 |
Bile acid metabolism.
Topics: Animals; Bile Acids and Salts; Cholelithiasis; Cholestasis; Cholesterol; Diet; Glycine; Hormones; Hy | 1975 |
3 trials available for taurine and Bile Duct Obstruction
| Article | Year |
|---|---|
Two parenteral amino acid solutions and plasma levels of amino acids in the neonate: A randomized trial.
Topics: Amino Acids; Birth Weight; Cholestasis; Cysteine; Double-Blind Method; Electrolytes; Female; Gestati | 2019 |
Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health.
Topics: Adult; Bile Acids and Salts; Biliary Tract; Carrier Proteins; Cholagogues and Choleretics; Cholestas | 2012 |
Effect of taurine supplementation on hepatic function during short-term parenteral nutrition in the premature infant.
Topics: Animals; Cattle; Cholestasis; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Disease | 1984 |
34 other studies available for taurine and Bile Duct Obstruction
| Article | Year |
|---|---|
Combination of resveratrol and luteolin ameliorates α-naphthylisothiocyanate-induced cholestasis by regulating the bile acid homeostasis and suppressing oxidative stress.
Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Cholestasis; Homeostasis; Liver; Luteolin; | 2022 |
Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation.
Topics: Animals; Antioxidants; Bile Ducts; Cholestasis; Fibrosis; Inflammation; Ligation; Liver; Liver Cirrh | 2022 |
Radiosynthesis of N-¹¹C-Methyl-Taurine-Conjugated Bile Acids and Biodistribution Studies in Pigs by PET/CT.
Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Chromatography, Thin Layer; Female; Isotope Labeli | 2016 |
Taurine zinc solid dispersions enhance bile-incubated L02 cell viability and improve liver function by inhibiting ERK2 and JNK phosphorylation during cholestasis.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Bile Ducts; Bilirubin; Cell L | 2016 |
Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver.
Topics: Animals; Apoptosis; Bile; Bile Acids and Salts; Carcinoma, Hepatocellular; Cholangitis; Cholestasis; | 2010 |
Intestinal synthesis and secretion of bile salts as an adaptation to developmental biliary atresia in the sea lamprey.
Topics: Animals; Bile Acids and Salts; Biliary Atresia; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Chroma | 2012 |
Taurine supplementation induces multidrug resistance protein 2 and bile salt export pump expression in rats and prevents endotoxin-induced cholestasis.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2003 |
Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Carrier P | 2003 |
Taurine and cholestasis associated to TPN. Experimental study in rabbit model.
Topics: Amino Acids; Animals; Bile; Bile Acids and Salts; Cholestasis; Food, Formulated; Liver; Parenteral N | 2005 |
Differential diagnostic value in hepatobiliary disease of serum conjugated bile acid concentrations and some routine liver tests assessed by discriminant analysis.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bi | 1983 |
Taurine deficiency in the severe hepatic dysfunction complicating total parenteral nutrition.
Topics: Amino Acids; Cholestasis; Female; Humans; Infant, Newborn; Liver Diseases; Parenteral Nutrition; Par | 1984 |
Rapid determination of glycine- and taurine-conjugated bile acids in human bile by high-performance liquid chromatography.
Topics: Bile; Bile Acids and Salts; Cholelithiasis; Cholestasis; Chromatography, High Pressure Liquid; Commo | 1980 |
Diminution of an acute cyclosporin-induced cholestasis by tauroursodeoxycholate in the rat.
Topics: Animals; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Cyclosporine; Male; Rats; R | 1993 |
Protection against alpha-naphthylisothiocyanate-induced acute cholestasis in mice by a novel taurine conjugate of ursodeoxycholate (UR-906).
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Bile Acids and Salts; Bilirubin; Biomarkers | 1993 |
Pan-sulfation of bile salts markedly increases hydrophilicity and essentially abolishes self- and hetero-association with lecithin.
Topics: Bile Acids and Salts; Cholestasis; Glycine; Humans; Hydrogen-Ion Concentration; Liver Diseases; Memb | 1993 |
Different protective effects of tauroursodeoxycholate, ursodeoxycholate, and 23-methyl-ursodeoxycholate against taurolithocholate-induced cholestasis.
Topics: Animals; Cholelithiasis; Cholestasis; Isomerism; Male; Rats; Rats, Sprague-Dawley; Taurine; Taurolit | 1996 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Prevention of liver failure in parenteral nutrition-dependent children with short bowel syndrome.
Topics: Bacterial Translocation; Catheters, Indwelling; Child; Child, Preschool; Cholestasis; Clinical Proto | 1997 |
Taurine: protective properties against ethanol-induced hepatic steatosis and lipid peroxidation during chronic ethanol consumption in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosine Triphosphate; Alcoholism; Anima | 1998 |
Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.
Topics: Adenosine Diphosphate; Animals; Bile Acids and Salts; Cell Membrane Permeability; Cholestasis; Energ | 2000 |
Hepatic taurine concentration and dietary taurine as regulators of bile acid conjugation with taurine.
Topics: Bile; Bile Acids and Salts; Cholestasis; Diet; Enterohepatic Circulation; Humans; Liver; Taurine | 1978 |
Taurine: an essential amino acid to prevent cholestasis in neonates?
Topics: Amino Acids, Essential; Animals; Cholestasis; Humans; Infant; Infant, Newborn; Parenteral Nutrition, | 1992 |
Tauro-beta-muricholate preserves choleresis and prevents taurocholate-induced cholestasis in colchicine-treated rat liver.
Topics: Animals; Bicarbonates; Bile; Cholagogues and Choleretics; Cholestasis; Cholic Acids; Colchicine; In | 1992 |
The effect of taurine on the cholestatic potential of sulfated lithocholate and its conjugates.
Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Guinea Pigs; Lithocholic Acid; Liver; Male; Taurin | 1991 |
Liver dysfunction in cystic fibrosis--beneficial effect of bile acid treatment.
Topics: Bile Acids and Salts; Child; Cholestasis; Cystic Fibrosis; Humans; Liver Function Tests; Taurine; Ur | 1991 |
Altered glycine and taurine conjugation of bile acids following aluminum administration to rats.
Topics: Aluminum; Animals; Bile Acids and Salts; Cholestasis; Glycine; Male; Rats; Rats, Inbred Strains; Tau | 1989 |
Amino acid mixture designed to maintain normal plasma amino acid patterns in infants and children requiring parenteral nutrition.
Topics: Amino Acids; Bilirubin; Body Weight; Child; Child, Preschool; Cholestasis; Cysteine; Electrolytes; E | 1987 |
Measurement of direct bilirubin by use of bilirubin oxidase.
Topics: Bilirubin; Biliverdine; Cholestasis; Diazonium Compounds; Humans; Indicators and Reagents; Oxidoredu | 1987 |
The synthesis of cholic acid conjugates in human liver. An analysis of factors controlling the subcellular synthesis of bile acid conjugates in normal and cholestatic conditions.
Topics: Acid Phosphatase; Acyltransferases; Adenosine Triphosphatases; Bile Acids and Salts; Bilirubin; Bind | 1967 |
[Significance of bile acid metabolism in the pathogenesis of surgical diseases].
Topics: Bile Acids and Salts; Biliary Fistula; Blind Loop Syndrome; Cholelithiasis; Cholestasis; Cholesterol | 1973 |
Serum bile acids in primary biliary cirrhosis.
Topics: Bile Acids and Salts; Cholestasis; Cholestyramine Resin; Glycine; Humans; Hydroxylation; Liver Cirrh | 1972 |
Cholestasis induced by sodium taurolithocholate in isolated hamster liver.
Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts, Intrahepatic; Cholestasis; Chromatography, Gas; Chr | 1971 |
Biochemical and morphological parameters of taurolithocholate-induced cholestasis.
Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Bilirubin; C | 1971 |
Serum bile acids in liver disease.
Topics: Adult; Aged; Bile Acids and Salts; Biliary Tract Diseases; Cholanes; Cholestasis; Colitis, Ulcerativ | 1971 |
Clinical aspects of bile acid metabolism.
Topics: Bile; Bile Acids and Salts; Celiac Disease; Cholestasis; Cholesterol; Fatty Acids, Nonesterified; Gl | 1968 |