Page last updated: 2024-10-20

taurine and Bacterial Disease

taurine has been researched along with Bacterial Disease in 21 studies

Research Excerpts

ExcerptRelevanceReference
"This study shows that catheter filling with a solution containing the antimicrobial taurolidine may significantly reduce the incidence of catheter-related sepsis."9.11Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution. ( Betjes, MG; van Agteren, M, 2004)
"As secondary peritonitis is associated with a significant cytokine release that is compartementalized in the peritoneal cavity, taurolidine is bactericidal, antiendotoxic, and antiadherent locally and, on the other hand, may modulate the systemic cytokine-mediated inflammatory response after being adsorbed systemically by the peritoneum."6.40[Adjuvant therapy of peritonitis with taurolidine. Modulation of mediator liberation]. ( Staubach, KH, 1997)
"This study shows that catheter filling with a solution containing the antimicrobial taurolidine may significantly reduce the incidence of catheter-related sepsis."5.11Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution. ( Betjes, MG; van Agteren, M, 2004)
"Taurolidine has demonstrated inhibition of biofilm formation in vitro."2.77Biofilm formation in long-term central venous catheters in children with cancer: a randomized controlled open-labelled trial of taurolidine versus heparin. ( Funch, P; Fuursted, K; Handrup, MM; Møller, JK; Schrøder, H, 2012)
"As secondary peritonitis is associated with a significant cytokine release that is compartementalized in the peritoneal cavity, taurolidine is bactericidal, antiendotoxic, and antiadherent locally and, on the other hand, may modulate the systemic cytokine-mediated inflammatory response after being adsorbed systemically by the peritoneum."2.40[Adjuvant therapy of peritonitis with taurolidine. Modulation of mediator liberation]. ( Staubach, KH, 1997)
"Taurolidine is an anti-infective agent with an unusually broad spectrum of effectivity against gram-positive and gram-negative bacteria, anaerobic organisms, and fungi."1.30[The influence of taurolidine on physiological and pathological blood coagulation and implications for its use]. ( Reinmüller, J, 1999)
" However, by increasing the dosage of taurolin, survival is prolonged and mortality reduced."1.26The in vitro and in vivo activity of taurolin against anaerobic pathogenic organisms. ( Brodhage, H; Browne, MK; Leslie, GB; Pfirrman, RW, 1977)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's10 (47.62)18.2507
2000's3 (14.29)29.6817
2010's1 (4.76)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Stacy, A1
Andrade-Oliveira, V1
McCulloch, JA1
Hild, B1
Oh, JH1
Perez-Chaparro, PJ1
Sim, CK1
Lim, AI1
Link, VM1
Enamorado, M1
Trinchieri, G1
Segre, JA1
Rehermann, B1
Belkaid, Y1
Weber, M1
Meyer, F1
Halloul, Z1
Handrup, MM1
Fuursted, K1
Funch, P1
Møller, JK1
Schrøder, H1
Betjes, MG1
van Agteren, M1
Nentwig, GH1
Kniha, H1
Linder, MM1
Ott, W1
Wesch, G1
Reding, R1
Pfirrman, RW2
Reisser, C1
Mielenz, H1
Jünemann, K1
Zimmermann, M2
Preac-Mursic, V1
Popović, M1
Dugalni, D1
Milićević, M1
Petrović, M1
Zuvela, M1
Knezević, S1
Janković, Z1
Focht, J1
Nösner, K1
Staubach, KH1
Reinmüller, J1
Shah, CB1
Mittelman, MW1
Costerton, JW1
Parenteau, S1
Pelak, M1
Arsenault, R1
Mermel, LA1
Browne, MK3
Leslie, GB1
Brodhage, H1
MacKenzie, M1
Doyle, PJ1
Billing, A1
Fröhlich, D1
Ruckdeschel, G1
Burri, C1
Kalas, L1
Kárpáti, V1
McCartney, AC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective, Randomized, Controlled Trial Evaluating the Efficacy of a Lock-therapy With a Solution of Taurolidine/Citrate (TauroLock) vs Standard Saline Solution for the Primary Prevention of Catheter-related Infections (CLI) in Adult Patients Wtih a Non[NCT02279121]162 participants (Actual)Interventional2014-11-30Completed
A Randomised Study of Taurolock for the Locking of Tunneled Central Venous Catheters in Children With Malignant Diseases.[NCT00735813]Phase 3129 participants (Actual)Interventional2008-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for taurine and Bacterial Disease

ArticleYear
[Adjuvant therapy of peritonitis with taurolidine. Modulation of mediator liberation].
    Langenbecks Archiv fur Chirurgie, 1997, Volume: 382, Issue:4 Suppl 1

    Topics: Anti-Infective Agents; Bacterial Infections; Combined Modality Therapy; Cytokines; Humans; Peritonit

1997
[Treatment of local infection with taurolin].
    Aktuelle Probleme in Chirurgie und Orthopadie, 1990, Volume: 34

    Topics: Anti-Infective Agents, Local; Bacterial Infections; Chronic Disease; Fracture Fixation, Internal; Ge

1990

Trials

6 trials available for taurine and Bacterial Disease

ArticleYear
Biofilm formation in long-term central venous catheters in children with cancer: a randomized controlled open-labelled trial of taurolidine versus heparin.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2012, Volume: 120, Issue:10

    Topics: Adolescent; Anti-Bacterial Agents; Anticoagulants; Antineoplastic Agents; Bacterial Infections; Biof

2012
Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:6

    Topics: Anti-Infective Agents; Bacterial Infections; Catheterization, Central Venous; Catheters, Indwelling;

2004
Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:6

    Topics: Anti-Infective Agents; Bacterial Infections; Catheterization, Central Venous; Catheters, Indwelling;

2004
Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:6

    Topics: Anti-Infective Agents; Bacterial Infections; Catheterization, Central Venous; Catheters, Indwelling;

2004
Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:6

    Topics: Anti-Infective Agents; Bacterial Infections; Catheterization, Central Venous; Catheters, Indwelling;

2004
[Antibacterial therapy of purulent peritonitis: a prospective randomized study on the effects of antibiotics and taurolin, a new chemotherapeutic and antiendotoxic agent (author's transl)].
    Chirurgisches Forum fur experimentelle und klinische Forschung, 1980

    Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Therapy, Combination; Endotoxins; Female; Humans;

1980
C controlled trial of taurolin in established bacterial peritonitis.
    Surgery, gynecology & obstetrics, 1978, Volume: 146, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Infections; Child; Clinical Trials

1978
[Treatment of orofacial infections. Taurolidine--an alternative treatment concept to antimicrobial chemotherapy].
    Fortschritte der Medizin, 1992, Oct-20, Volume: 110, Issue:29

    Topics: Administration, Topical; Anti-Infective Agents, Local; Bacterial Infections; Humans; Mouth Diseases;

1992
Clinical studies on administration of taurolin in severe sepsis: a preliminary study.
    Progress in clinical and biological research, 1988, Volume: 272

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Clinical Trials as Topic; Endotoxins; Female; Hum

1988

Other Studies

13 other studies available for taurine and Bacterial Disease

ArticleYear
Infection trains the host for microbiota-enhanced resistance to pathogens.
    Cell, 2021, 02-04, Volume: 184, Issue:3

    Topics: Animals; Bacterial Infections; Colony Count, Microbial; Gastrointestinal Microbiome; Host-Pathogen I

2021
[Spectrum of indications and perioperative management in i. v. port-a-cath explantation--alternative administration of taurolin in case of i. v. port-a-cath infection].
    Zentralblatt fur Chirurgie, 2009, Volume: 134, Issue:4

    Topics: Adult; Aged; Anti-Infective Agents; Bacteremia; Bacterial Infections; Catheters, Indwelling; Device

2009
[Local chemotherapy of bone infections with Taurolin].
    Zahnarztliche Praxis, 1984, Oct-12, Volume: 35, Issue:10

    Topics: Adult; Anti-Infective Agents; Bacterial Infections; Humans; Jaw Diseases; Osteomyelitis; Taurine; Th

1984
Taurolidine peritoneal lavage as prophylaxis against infection after elective colorectal surgery.
    The British journal of surgery, 1995, Volume: 82, Issue:4

    Topics: Anti-Infective Agents, Local; Bacterial Infections; Colon; Elective Surgical Procedures; Humans; Per

1995
[Initial clinical experience with taurolidin instillation into the area of the middle area].
    HNO, 1994, Volume: 42, Issue:10

    Topics: Adult; Anti-Infective Agents, Local; Audiometry, Pure-Tone; Bacterial Infections; Female; Follow-Up

1994
The antimicrobial actions of taurolin and other preparations on the pathogenic spectrum in dentoalveolar infections.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:3

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Adhesion; Bacterial Infections; Chlorhexidine; Chlortetra

1993
[Use of taurolin in the prevention of septic complications in emergency abdominal surgery].
    Acta chirurgica Iugoslavica, 1991, Volume: 38, Issue:1

    Topics: Abdomen; Anti-Infective Agents; Bacterial Infections; Emergencies; Humans; Intraoperative Care; Peri

1991
[1996 pathogen incidence and resistance status in peritonitis].
    Langenbecks Archiv fur Chirurgie, 1997, Volume: 382, Issue:4 Suppl 1

    Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Microbial; Humans; Microbial Sensitivi

1997
[The influence of taurolidine on physiological and pathological blood coagulation and implications for its use].
    Zentralblatt fur Chirurgie, 1999, Volume: 124 Suppl 4

    Topics: Anti-Infective Agents, Local; Bacterial Infections; Blood Coagulation; Gram-Negative Bacteria; Gram-

1999
Antimicrobial activity of a novel catheter lock solution.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Bacterial Infections; Biofilms; Catheterizat

2002
The in vitro and in vivo activity of taurolin against anaerobic pathogenic organisms.
    Surgery, gynecology & obstetrics, 1977, Volume: 145, Issue:6

    Topics: Animals; Bacterial Infections; Bacteroides; Bacteroides Infections; Clostridium Infections; Clostrid

1977
[The effect of taurolin on endogenous immunity and pathogen elimination in human peritonitis].
    Langenbecks Archiv fur Chirurgie, 1992, Volume: 377, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Local; Bacterial Infections; Colony Count, Microbial

1992
[Treatment of post-traumatic osteomyelitis with Taurolin Gel].
    Magyar traumatologia, orthopaedia es helyreallito sebeszet, 1987, Volume: 30, Issue:1

    Topics: Administration, Topical; Adult; Arm Injuries; Bacterial Infections; Fracture Fixation, Internal; Fra

1987