Page last updated: 2024-10-20

taurine and Bacteremia

taurine has been researched along with Bacteremia in 22 studies

Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.

Research Excerpts

ExcerptRelevanceReference
"Taurolidine-citrate use did not decrease all-cause bacteremia and was associated with a greater need for thrombolytic treatment."9.14A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis. ( Al-Sayed, T; Bhat, R; Cheesbrough, JS; Curry, A; Diggle, P; Ebah, L; Heap, M; Millband, N; Mitra, S; Saxena, R; Schulz, M; Solomon, LR; Waterhouse, D, 2010)
"Preliminary evidence from some studies suggests that taurolidine-citrate locks decrease catheter-related bacteremia (CRB), which is a major cause of morbidity and mortality in patients using intravascular catheters."8.90Preventing catheter-related bacteremia with taurolidine-citrate catheter locks: a systematic review and meta-analysis. ( Chen, L; Deng, J; Liu, H; Wu, Y; Yuan, L, 2014)
"Taurolidine-citrate use did not decrease all-cause bacteremia and was associated with a greater need for thrombolytic treatment."5.14A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis. ( Al-Sayed, T; Bhat, R; Cheesbrough, JS; Curry, A; Diggle, P; Ebah, L; Heap, M; Millband, N; Mitra, S; Saxena, R; Schulz, M; Solomon, LR; Waterhouse, D, 2010)
"Preliminary evidence from some studies suggests that taurolidine-citrate locks decrease catheter-related bacteremia (CRB), which is a major cause of morbidity and mortality in patients using intravascular catheters."4.90Preventing catheter-related bacteremia with taurolidine-citrate catheter locks: a systematic review and meta-analysis. ( Chen, L; Deng, J; Liu, H; Wu, Y; Yuan, L, 2014)
"Taurolidine is an antimicrobial agent that was originally used in the local treatment of peritonitis and was shown to be effective in the prevention of catheter-related bloodstream infections (CR-BSI)."2.71Taurolidine is effective in the treatment of central venous catheter-related bloodstream infections in cancer patients. ( Koldehoff, M; Zakrzewski, JL, 2004)
"Catheter-related bacteremia is a major cause of morbidity among hemodialysis patients."2.42Dialysis catheter-related bacteremia: treatment and prophylaxis. ( Allon, M, 2004)
"Taurolidine is a molecule with anti-endotoxic, anti-microbial and anti-inflammatory properties that inhibits bacterial adhesion, allowing for its use as lock therapy for the prevention of catheter-related bloodstream infections (CRBSI) in long-term central venous catheters (CVC)."1.62[Taurolidine for the prevention of catheter-related infections in children with intestinal insufficiency: preliminary experience in a Chilean tertiary hospital]. ( Haro, C; Jordán P, M; Puchi, A, 2021)
"Gentamicine was more effective than vancomycine."1.51In vitro comparison of efficacy of catheter locks in the treatment of catheter related blood stream infection. ( Blaha, V; Lasticova, M; Ryskova, L; Safranek, R; Visek, J, 2019)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.09)18.2507
2000's5 (22.73)29.6817
2010's11 (50.00)24.3611
2020's4 (18.18)2.80

Authors

AuthorsStudies
Strauss, J1
Boctor, DL1
Silverman, JA1
Casey, L1
Jordán P, M1
Haro, C1
Puchi, A1
Neusser, MA1
Bobe, I1
Hammermeister, A1
Wittmann, U1
Wouters, Y1
Theilla, M1
Singer, P1
Tribler, S1
Jeppesen, PB1
Pironi, L1
Vinter-Jensen, L1
Rasmussen, HH1
Rahman, F1
Wanten, GJA1
Clark, JE1
Graham, N1
Kleidon, T1
Ullman, A1
Visek, J1
Ryskova, L1
Safranek, R1
Lasticova, M1
Blaha, V1
Chong, CY1
Ong, RY1
Seah, VX1
Tan, NW1
Chan, MY1
Soh, SY1
Ong, C1
Lim, AS1
Thoon, KC1
Reitzel, RA1
Rosenblatt, J1
Chaftari, AM1
Raad, II1
Klek, S1
Szczepanek, K1
Hermanowicz, A1
Galas, A1
Saunders, J1
Naghibi, M1
Leach, Z1
Parsons, C1
King, A1
Smith, T1
Stroud, M1
Liu, H2
Deng, J1
Chen, L1
Yuan, L1
Wu, Y1
Murray, EC1
Deighan, C1
Geddes, C1
Thomson, PC1
Olthof, ED1
Versleijen, MW1
Huisman-de Waal, G1
Feuth, T1
Kievit, W1
Wanten, GJ1
Hulshof, EC1
Hanff, LM1
Olieman, J1
de Vette, S1
Driessen, GJ1
Meeussen, C1
Escher, JC1
Weber, M1
Meyer, F1
Halloul, Z1
Solomon, LR1
Cheesbrough, JS1
Ebah, L1
Al-Sayed, T1
Heap, M1
Millband, N1
Waterhouse, D1
Mitra, S1
Curry, A1
Saxena, R1
Bhat, R1
Schulz, M1
Diggle, P1
Allon, M2
Koldehoff, M1
Zakrzewski, JL1
Jurewitsch, B1
Jeejeebhoy, KN1
Willatts, SM1
Speller, DC1
Winter, RJ1
Rosman, C1
Westerveld, GJ1
van Oeveren, W1
Kooi, K1
Bleichrodt, RP1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Taurolidine 2% Catheter Locking to Prevent Catheter-related Bloodstream Infections in Patients on Home Parenteral Nutrition With a High Infection Risk and Those With a New Central Venous Access Device[NCT01826526]105 participants (Actual)Interventional2013-06-30Completed
Prospective, Randomized, Controlled Trial Evaluating the Efficacy of a Lock-therapy With a Solution of Taurolidine/Citrate (TauroLock) vs Standard Saline Solution for the Primary Prevention of Catheter-related Infections (CLI) in Adult Patients Wtih a Non[NCT02279121]162 participants (Actual)Interventional2014-11-30Completed
Short Daily Alcohol Locks for the Prevention of Tunneled Catheter Infection in Patients With Haematological Disease. Randomised Placebo Controlled Trial[NCT00122642]Phase 2/Phase 3440 participants (Anticipated)Interventional2005-08-31Completed
[NCT00294502]Phase 4120 participants Interventional2003-09-30Completed
The AOT (Acridine Orange and Taurolidine) Trial: a Survey on Diagnosis and Prevention of Catheter-Related Infections in Patients on Home Parenteral Nutrition[NCT00321165]Phase 360 participants (Anticipated)Interventional2006-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for taurine and Bacteremia

ArticleYear
Epidemiology of Infectious and Noninfectious Catheter Complications in Patients Receiving Home Parenteral Nutrition: A Systematic Review and Meta-Analysis.
    JPEN. Journal of parenteral and enteral nutrition, 2019, Volume: 43, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infe

2019
Preventing catheter-related bacteremia with taurolidine-citrate catheter locks: a systematic review and meta-analysis.
    Blood purification, 2014, Volume: 37, Issue:3

    Topics: Anti-Infective Agents; Anticoagulants; Bacteremia; Citric Acid; Female; Humans; Male; PubMed; Taurin

2014
Dialysis catheter-related bacteremia: treatment and prophylaxis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2004, Volume: 44, Issue:5

    Topics: Antibiotic Prophylaxis; Bacteremia; Catheterization, Central Venous; Catheters, Indwelling; Gentamic

2004

Trials

7 trials available for taurine and Bacteremia

ArticleYear
Randomised clinical trial: 2% taurolidine versus 0.9% saline locking in patients on home parenteral nutrition.
    Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:4

    Topics: Adult; Aged; Bacteremia; Catheter-Related Infections; Double-Blind Method; Equivalence Trials as Top

2018
Taurolidine-citrate lock solution for the prevention of central line-associated bloodstream infection in paediatric haematology-oncology and gastrointestinal failure patients with high baseline central-line associated bloodstream infection rates.
    Journal of paediatrics and child health, 2020, Volume: 56, Issue:1

    Topics: Adolescent; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Central Venous

2020
Taurolidine lock in home parenteral nutrition in adults: results from an open-label randomized controlled clinical trial.
    JPEN. Journal of parenteral and enteral nutrition, 2015, Volume: 39, Issue:3

    Topics: Adult; Anti-Infective Agents; Bacteremia; Catheter-Related Infections; Catheterization, Central Veno

2015
A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2010, Volume: 55, Issue:6

    Topics: Adult; Aged; Anti-Infective Agents; Anticoagulants; Bacteremia; Catheters, Indwelling; Citric Acid;

2010
Prophylaxis against dialysis catheter-related bacteremia with a novel antimicrobial lock solution.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Jun-15, Volume: 36, Issue:12

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Catheterization; Catheters, Indwelling; F

2003
Prophylaxis against dialysis catheter-related bacteremia with a novel antimicrobial lock solution.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Jun-15, Volume: 36, Issue:12

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Catheterization; Catheters, Indwelling; F

2003
Prophylaxis against dialysis catheter-related bacteremia with a novel antimicrobial lock solution.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Jun-15, Volume: 36, Issue:12

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Catheterization; Catheters, Indwelling; F

2003
Prophylaxis against dialysis catheter-related bacteremia with a novel antimicrobial lock solution.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Jun-15, Volume: 36, Issue:12

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Catheterization; Catheters, Indwelling; F

2003
Taurolidine is effective in the treatment of central venous catheter-related bloodstream infections in cancer patients.
    International journal of antimicrobial agents, 2004, Volume: 24, Issue:5

    Topics: Adult; Anti-Infective Agents; Bacteremia; Catheterization, Central Venous; Female; Humans; Male; Neo

2004
Incidence of gram-negative bacteraemia in sepsis syndrome. Implications for immunotherapy.
    Anaesthesia, 1994, Volume: 49, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteremia; Critical Care; Double

1994

Other Studies

12 other studies available for taurine and Bacteremia

ArticleYear
Mechanical Complications in Central Lines Using Taurolidine Versus Ethanol Lock Therapy in Children With Intestinal Failure.
    Journal of pediatric gastroenterology and nutrition, 2022, 06-01, Volume: 74, Issue:6

    Topics: Bacteremia; Canada; Catheter-Related Infections; Catheterization, Central Venous; Central Venous Cat

2022
[Taurolidine for the prevention of catheter-related infections in children with intestinal insufficiency: preliminary experience in a Chilean tertiary hospital].
    Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2021, Volume: 38, Issue:1

    Topics: Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Child; Chile; Humans; Infa

2021
A 2% taurolidine catheter lock solution prevents catheter-related bloodstream infection (CRBSI) and catheter dysfunction in hemodialysis patients.
    British journal of nursing (Mark Allen Publishing), 2021, Jul-22, Volume: 30, Issue:14

    Topics: Bacteremia; Catheter-Related Infections; Central Venous Catheters; Equipment Failure; Humans; Renal

2021
Taurolidine-Citrate Line Locks Prevent Recurrent Central Line-Associated Bloodstream Infection in Pediatric Patients.
    The Pediatric infectious disease journal, 2019, Volume: 38, Issue:1

    Topics: Adolescent; Anti-Infective Agents, Local; Bacteremia; Catheter-Related Infections; Catheterization,

2019
In vitro comparison of efficacy of catheter locks in the treatment of catheter related blood stream infection.
    Clinical nutrition ESPEN, 2019, Volume: 30

    Topics: Anti-Bacterial Agents; Bacteremia; Candida; Catheter-Related Infections; Colony Count, Microbial; Eq

2019
Taurolidine locks significantly reduce the incidence of catheter-related blood stream infections in high-risk patients on home parenteral nutrition.
    European journal of clinical nutrition, 2015, Volume: 69, Issue:2

    Topics: Anti-Infective Agents, Local; Bacteremia; Catheter-Related Infections; Clinical Protocols; Humans; I

2015
Taurolidine-citrate-heparin catheter lock solution reduces staphylococcal bacteraemia rates in haemodialysis patients.
    QJM : monthly journal of the Association of Physicians, 2014, Volume: 107, Issue:12

    Topics: Anti-Infective Agents; Anticoagulants; Bacteremia; Catheterization, Central Venous; Catheters, Indwe

2014
Taurolidine lock is superior to heparin lock in the prevention of catheter related bloodstream infections and occlusions.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Adult; Aged; Bacteremia; Catheter Obstruction; Catheter-Related Infections; Female; Heparin; Humans;

2014
Taurolidine in Pediatric Home Parenteral Nutrition Patients.
    The Pediatric infectious disease journal, 2017, Volume: 36, Issue:2

    Topics: Anti-Infective Agents; Bacteremia; Catheter-Related Infections; Child, Preschool; Humans; Infant; In

2017
[Spectrum of indications and perioperative management in i. v. port-a-cath explantation--alternative administration of taurolin in case of i. v. port-a-cath infection].
    Zentralblatt fur Chirurgie, 2009, Volume: 134, Issue:4

    Topics: Adult; Aged; Anti-Infective Agents; Bacteremia; Bacterial Infections; Catheters, Indwelling; Device

2009
Taurolidine lock: the key to prevention of recurrent catheter-related bloodstream infections.
    Clinical nutrition (Edinburgh, Scotland), 2005, Volume: 24, Issue:3

    Topics: Adult; Anti-Infective Agents, Local; Bacteremia; Catheters, Indwelling; Humans; Middle Aged; Parente

2005
Effect of intraperitoneal antimicrobials on the concentration of bacteria, endotoxin, and tumor necrosis factor in abdominal fluid and plasma in rats.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1996, Volume: 28, Issue:5

    Topics: Abdomen; Animals; Anti-Bacterial Agents; Bacteremia; Bacteria; Body Fluids; Cilastatin; Colony Count

1996