Page last updated: 2024-10-20

taurine and Alcoholic Intoxication

taurine has been researched along with Alcoholic Intoxication in 14 studies

Alcoholic Intoxication: An acute brain syndrome which results from the excessive ingestion of ETHANOL or ALCOHOLIC BEVERAGES.

Research Excerpts

ExcerptRelevanceReference
" Physiological, subjective, and psychomotor measures were collected daily during each dosing cycle."2.71Alcohol effects during acamprosate treatment: a dose-response study in humans. ( Brasser, SM; Houtsmuller, EJ; McCaul, ME, 2004)
"Taurine (TAU) is an amino sulfonic acid that plays protective roles against neurochemical impairments induced by ethanol (EtOH)."1.38Behavioral effects of taurine pretreatment in zebrafish acutely exposed to ethanol. ( Blaser, RE; Braga, MM; Calcagnotto, ME; Campos, MM; Córdova, SD; de Oliveira, DL; Dias, RD; Leite, CE; Loss, CM; Mussulini, BH; Rico, EP; Rosemberg, DB; Souza, DO, 2012)
"Sleep-wake states were studied following withdrawal in 36 adult male wistar alcohol-dependent rats, after chronic administration of ethanol (10 g/kg/24 h) for 13 days."1.30Effects of muscimol or homotaurine on sleep-wake states in alcohol-dependent rats during withdrawal. ( Bajenaru, O; Dall'Ava-Santucci, J; Dinh-Xuan, AT; Emmanouilidis, E; Manicom, R; Poenaru, S; Rouhani, S; Tran, G, 1998)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's4 (28.57)18.2507
2000's2 (14.29)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, DW1
Nam, YK1
Kim, TK1
Kim, JH1
Kim, SY1
Min, JW1
Lee, JH1
Kim, HY1
Kim, DJ1
Choe, BY1
Adermark, L2
Clarke, RB2
Olsson, T1
Hansson, E1
Söderpalm, B2
Ericson, M2
Chau, P1
Rosemberg, DB1
Braga, MM1
Rico, EP1
Loss, CM1
Córdova, SD1
Mussulini, BH1
Blaser, RE1
Leite, CE1
Campos, MM1
Dias, RD1
Calcagnotto, ME1
de Oliveira, DL1
Souza, DO1
Wu, G1
Yang, J1
Lin, S1
Feng, Y1
Yang, Q1
Lv, Q1
Hu, J1
HAEKKINEN, HM1
KULONEN, E1
WALLGREN, H1
Brasser, SM1
McCaul, ME1
Houtsmuller, EJ1
Ferreira, SE1
de Mello, MT1
Pompéia, S1
de Souza-Formigoni, ML1
Dahchour, A1
Quertemont, E1
De Witte, P2
Riesselmann, B1
Rosenbaum, F1
Schneider, V1
Rouhani, S1
Dall'Ava-Santucci, J1
Bajenaru, O1
Emmanouilidis, E1
Tran, G1
Manicom, R1
Dinh-Xuan, AT1
Poenaru, S1
Gewiss, M1
Heidbreder, C1
Opsomer, L1
Durbin, P1
Liskow, BI1
Goodwin, DW1
Iida, S1
Hisada, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acamprosate for Central Nervous System Hyperexcitability and Neuroadaptation in Alcohol Withdrawal[NCT00106106]Phase 256 participants (Actual)Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Ratio of Glutamate to Creatine in the Anterior Cingulate of the Brain, Measured on Day 25

The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 25

InterventionRatio of glutamate to creatine (Mean)
Placebo1.350375
Acamprosate1.166667

Ratio of Glutamate to Creatine in the Anterior Cingulate of the Brain, Measured on Day 4

The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 4

InterventionRatio of glutamate to creatine (Mean)
Placebo1.256772
Acamprosate1.294178

Reviews

1 review available for taurine and Alcoholic Intoxication

ArticleYear
Pharmacological treatment of alcohol intoxication, withdrawal and dependence: a critical review.
    Journal of studies on alcohol, 1987, Volume: 48, Issue:4

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Antidepressive Agents, Tricyclic; Bromocript

1987

Trials

2 trials available for taurine and Alcoholic Intoxication

ArticleYear
Alcohol effects during acamprosate treatment: a dose-response study in humans.
    Alcoholism, clinical and experimental research, 2004, Volume: 28, Issue:7

    Topics: Acamprosate; Adult; Alcohol Drinking; Alcoholic Intoxication; Analysis of Variance; Dose-Response Re

2004
Effects of energy drink ingestion on alcohol intoxication.
    Alcoholism, clinical and experimental research, 2006, Volume: 30, Issue:4

    Topics: Adult; Alcoholic Intoxication; Beverages; Breath Tests; Caffeine; Energy Intake; Ethanol; Humans; Ma

2006

Other Studies

11 other studies available for taurine and Alcoholic Intoxication

ArticleYear
Dose-dependent influence of short-term intermittent ethanol intoxication on cerebral neurochemical changes in rats detected by ex vivo proton nuclear magnetic resonance spectroscopy.
    Neuroscience, 2014, Mar-14, Volume: 262

    Topics: Alanine; Alcoholic Intoxication; Animals; Aspartic Acid; Body Weight; Central Nervous System Depress

2014
Implications for glycine receptors and astrocytes in ethanol-induced elevation of dopamine levels in the nucleus accumbens.
    Addiction biology, 2011, Volume: 16, Issue:1

    Topics: Alcoholic Intoxication; Animals; Astrocytes; Dopamine; Ethanol; Furosemide; Glycine Agents; Male; Ne

2011
Rising taurine and ethanol concentrations in nucleus accumbens interact to produce dopamine release after ethanol administration.
    Addiction biology, 2011, Volume: 16, Issue:3

    Topics: Alcoholic Intoxication; Animals; beta-Alanine; Brain Mapping; Dopamine; Ethanol; Extracellular Fluid

2011
Behavioral effects of taurine pretreatment in zebrafish acutely exposed to ethanol.
    Neuropharmacology, 2012, Volume: 63, Issue:4

    Topics: Alcoholic Intoxication; Animals; Anxiety; Behavior, Animal; Brain; Dietary Supplements; Disease Mode

2012
Taurine and Chinese traditional medicine accelerate alcohol metabolism in mice.
    Advances in experimental medicine and biology, 2013, Volume: 776

    Topics: Alcohol Dehydrogenase; Alcoholic Intoxication; Alcohols; Aldehyde Dehydrogenase; Animals; Drugs, Chi

2013
THE EFFECT OF ETHANOL AND ELECTRICAL STIMULATION ON THE AMINO ACID METABOLISM OF RAT-BRAIN-CORTEX SLICES IN VITRO.
    The Biochemical journal, 1963, Volume: 88

    Topics: Alanine; Alcoholic Intoxication; Amino Acids; Aminobutyrates; Ammonium Chloride; Aspartic Acid; Brai

1963
Acute ethanol increases taurine but neither glutamate nor GABA in the nucleus accumbens of male rats: a microdialysis study.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1994, Volume: 29, Issue:5

    Topics: Alcoholic Intoxication; Animals; Chromatography, High Pressure Liquid; Ethanol; gamma-Aminobutyric A

1994
[Alcohol and energy drink--can combined consumption of both beverages modify automobile driving fitness?].
    Blutalkohol, 1996, Volume: 33, Issue:4

    Topics: Accidents, Traffic; Adult; Alcohol Drinking; Alcoholic Intoxication; Beverages; Caffeine; Dose-Respo

1996
Effects of muscimol or homotaurine on sleep-wake states in alcohol-dependent rats during withdrawal.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:4

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Behavior, Animal; Body Weight; Central Nervous System D

1998
Acamprosate and diazepam differentially modulate alcohol-induced behavioural and cortical alterations in rats following chronic inhalation of ethanol vapour.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1991, Volume: 26, Issue:2

    Topics: Acamprosate; Administration, Inhalation; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Anima

1991
Proceedings: Effect of taurine and other amino acids on the depressant effects of ethanol in mice.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:0

    Topics: Alcoholic Intoxication; Amino Acids; Animals; Ethanol; Humans; Mice; Taurine

1974