Page last updated: 2024-10-20

taurine and Alcohol-Related Disorders

taurine has been researched along with Alcohol-Related Disorders in 34 studies

Alcohol-Related Disorders: Disorders related to or resulting from abuse or misuse of alcohol.

Research Excerpts

ExcerptRelevanceReference
"Acamprosate has been available in the United States for treating alcohol use disorders (AUDs) for nearly a decade, yet few studies have examined its use within AUD treatment organizations."2.79Dissemination, adoption, and implementation of acamprosate for treating alcohol use disorders. ( Knudsen, HK; Roman, PM, 2014)
"Acamprosate is a widely utilized, efficacious treatment for relapse prevention in alcohol dependent patients."2.74The effect of acamprosate on alcohol craving and correlation with hypothalamic pituitary adrenal (HPA) axis hormones and beta-endorphin. ( Franck, J; Hammarberg, A; Jayaram-Lindström, N; Nylander, I; Reid, MS; Zhou, Q, 2009)
" Factors such as dosing frequency, potential adverse events, and availability of treatments may guide medication choice."2.50Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis. ( Amick, HR; Bobashev, G; Feltner, C; Garbutt, JC; Gass, CE; Jonas, DE; Kim, MM; Rowe, CJ; Shanahan, E; Thomas, K; Wines, R, 2014)
"Acamprosate appears to be an effective and safe treatment strategy for supporting continuous abstinence after detoxification in alcohol dependent patients."2.46Acamprosate for alcohol dependence. ( Hackl-Herrwerth, A; Lehert, P; Leucht, S; Rösner, S; Soyka, M; Vecchi, S, 2010)
"Medications for treating alcohol dependence primarily have been adjunctive interventions, and only three medications--disulfiram, naltrexone, and acamprosate--are approved for this indication by the U."2.43Medications for treating alcohol dependence. ( Williams, SH, 2005)
"Acamprosate has been widely used since the Food and Drug Administration approved the medication for treatment of alcohol use disorders (AUDs) in 2004."1.42Elevated baseline serum glutamate as a pharmacometabolomic biomarker for acamprosate treatment outcome in alcohol-dependent subjects. ( Biernacka, JM; Choi, DS; Frye, MA; Geske, JR; Hinton, DJ; Ho, AM; Karpyak, VM; Nam, HW; Prieto, ML; Weinshilboum, RM, 2015)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (38.24)29.6817
2010's21 (61.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lyon, J1
Soyka, M3
Zindel, LR1
Kranzler, HR2
Knudsen, HK2
Roman, PM2
Jonas, DE1
Amick, HR1
Feltner, C1
Bobashev, G1
Thomas, K1
Wines, R1
Kim, MM1
Shanahan, E1
Gass, CE1
Rowe, CJ1
Garbutt, JC1
Testino, G1
Leone, S1
Borro, P1
Witkiewitz, K2
Vowles, KE1
McCallion, E1
Frohe, T1
Kirouac, M1
Maisto, SA1
Mark, TL1
Lubran, R1
McCance-Katz, EF1
Chalk, M1
Richardson, J1
Nam, HW1
Karpyak, VM1
Hinton, DJ1
Geske, JR1
Ho, AM1
Prieto, ML1
Biernacka, JM1
Frye, MA1
Weinshilboum, RM1
Choi, DS1
Yumoto, Y1
Higuchi, S1
Helton, SG1
Lohoff, FW1
Bramness, JG1
Mann, K1
Wurst, FM1
Harris, AH1
Bowe, T1
Hagedorn, H1
Nevedal, A1
Finlay, AK1
Gidwani, R1
Rosen, C1
Kay, C1
Christopher, M1
Crits-Christoph, P1
Markell, HM1
Gibbons, MB1
Gallop, R1
Lundy, C1
Stringer, M1
Gastfriend, DR1
von der Goltz, C1
Vengeliene, V2
Bilbao, A1
Perreau-Lenz, S1
Pawlak, CR1
Kiefer, F1
Spanagel, R2
Hammarberg, A1
Nylander, I1
Zhou, Q1
Jayaram-Lindström, N1
Reid, MS1
Franck, J1
Zarkin, GA1
Bray, JW1
Aldridge, A1
Mills, M1
Cisler, RA1
Couper, D1
McKay, JR1
O'Malley, S1
Rösner, S1
Hackl-Herrwerth, A1
Leucht, S1
Lehert, P1
Vecchi, S1
Hunter-Reel, D1
Zweben, A1
Clark, DB1
Maisel, NC1
Blodgett, JC1
Wilbourne, PL1
Humphreys, K1
Finney, JW1
Kenna, GA1
McGeary, JE1
Swift, RM1
Williams, SH1
Morley, KC1
Teesson, M1
Reid, SC1
Sannibale, C1
Thomson, C1
Phung, N1
Weltman, M1
Bell, JR1
Richardson, K1
Haber, PS1
Swift, R1
McDonough, KP1
Peterson, AM1
Green, AI1
Drake, RE1
Brunette, MF1
Noordsy, DL1
Berglund, M1
Gorelick, D1
Hesselbrock, V1
Johnson, BA1
Möller, HJ1
Fiellin, DA1
Reid, MC1
O'Connor, PG1
Tedeschi, M1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep: A Randomized, Double-Blind, Placebo- Controlled Study[NCT05458609]Phase 314 participants (Anticipated)Interventional2023-02-09Enrolling by invitation
In Hospital Administration of Extended-Release Naltrexone for Alcohol Use Disorder: A Pilot Study of Feasibility and Acceptability[NCT05087771]Phase 40 participants (Actual)Interventional2022-03-31Withdrawn (stopped due to no longer randomized, drug being offered to all patients)
The Effect of N-acetylcysteine (NAC) on Treatment of Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial.[NCT03018236]Phase 4100 participants (Anticipated)Interventional2017-01-31Recruiting
A Pilot Study of N-acetylcysteine for Alcohol Use Disorder[NCT04964843]Phase 20 participants (Actual)Interventional2023-04-30Withdrawn (stopped due to Null results were posted from a neurometabolite study and a recent trial for AUD. Study may resume if more positive data emerge.)
Pilot Study of Combined Treatment for Veterans With Chronic Pain & Opiate Misuse[NCT02423772]37 participants (Actual)Interventional2014-08-31Completed
Participatory System Dynamics vs Audit and Feedback: A Cluster Randomized Trial of Mechanisms of Implementation Change to Expand Reach of Evidence-based Addiction and Mental Health Care[NCT04356274]720 participants (Anticipated)Interventional2019-02-01Enrolling by invitation
Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776]Phase 254 participants (Actual)Interventional2017-08-07Completed
Auricular Percutaneous Electrical Neural Field Stimulation in Short-Term Treatment of Alcohol Dependence- Neurohaemodynamic Correlates and Feasibility Study[NCT04106739]44 participants (Actual)Interventional2019-10-20Completed
Treatment for Alcohol Dependence With Gabapentin: A Double Blind Placebo Controlled Randomized Clinical Trial[NCT02771925]Phase 425 participants (Actual)Interventional2016-06-30Terminated (stopped due to Due to poor compliance of patients in the study.)
Phase Four Randomized, Multicentre, Open-Label, Comparative Trial Of Disulfiram, Nalterexone And Acamprosate In The Treatment Of Alcohol Dependence[NCT00435435]Phase 4243 participants Interventional2000-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Prefrontal GABA+ Concentrations

Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine3.90
Gabapentin3.93
Placebo Oral Tablet3.73

Prefrontal Glx Concentrations

Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition

Interventionmmol/kg (Mean)
N-Acetylcysteine21.59
Gabapentin21.69
Placebo Oral Tablet22.25

Reviews

15 reviews available for taurine and Alcohol-Related Disorders

ArticleYear
Pharmacotherapy of alcohol use disorders: seventy-five years of progress.
    Journal of studies on alcohol and drugs. Supplement, 2014, Volume: 75 Suppl 17

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Disulfiram; Fructose; Humans; Hypnotics

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.
    JAMA, 2014, May-14, Volume: 311, Issue:18

    Topics: Acamprosate; Alcohol-Related Disorders; Fructose; Harm Reduction; Humans; Naltrexone; Outpatients; R

2014
Treatment of alcohol dependence: recent progress and reduction of consumption.
    Minerva medica, 2014, Volume: 105, Issue:6

    Topics: Acamprosate; Age of Onset; Alcohol Deterrents; Alcohol-Related Disorders; Alcoholism; Binge Drinking

2014
[Pharmacological therapies for alcohol use disorder in Japan].
    Nihon rinsho. Japanese journal of clinical medicine, 2015, Volume: 73, Issue:9

    Topics: Acamprosate; Alcohol-Related Disorders; Alcohols; Humans; Japan; Naltrexone; Substance Withdrawal Sy

2015
Pharmacogenetics of alcohol use disorders and comorbid psychiatric disorders.
    Psychiatry research, 2015, Dec-15, Volume: 230, Issue:2

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Anxiety Disorders; Comorbidity; Depressi

2015
Acamprosate for alcohol dependence.
    The Cochrane database of systematic reviews, 2010, Sep-08, Issue:9

    Topics: Acamprosate; Adult; Alcohol Deterrents; Alcohol-Related Disorders; Diarrhea; Humans; Placebo Effect;

2010
New pharmacological treatment strategies for relapse prevention.
    Current topics in behavioral neurosciences, 2013, Volume: 13

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Animals; Disulfiram; Drugs, Investigatio

2013
Meta-analysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful?
    Addiction (Abingdon, England), 2013, Volume: 108, Issue:2

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Ethanol; Humans; Inactivation, Metabolic

2013
Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, part 1.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2004, Nov-01, Volume: 61, Issue:21

    Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Clinical Tria

2004
Medications for treating alcohol dependence.
    American family physician, 2005, Nov-01, Volume: 72, Issue:9

    Topics: Acamprosate; Adult; Aged; Alcohol Deterrents; Alcohol-Related Disorders; Alcoholism; Disulfiram; Dos

2005
Emerging approaches to managing alcohol dependence.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Mar-01, Volume: 64, Issue:5 Suppl 3

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Behavior Therapy; Brain; Disulfiram; Dru

2007
Improving adherence in patients with alcohol dependence: a new role for pharmacists.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Mar-01, Volume: 64, Issue:5 Suppl 3

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Behavior Therapy; Disulfiram; Humans; Na

2007
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2008, Volume: 9, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Biological Psychiatry; Carbamazepine; Di

2008
New therapies for alcohol problems: application to primary care.
    The American journal of medicine, 2000, Feb-15, Volume: 108, Issue:3

    Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Clinical Trials as Top

2000
Naltrexone and acamprosate. Using new drugs for alcohol dependence.
    Australian family physician, 2001, Volume: 30, Issue:5

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Australia; Clinical Trials as Topic; Fem

2001

Trials

5 trials available for taurine and Alcohol-Related Disorders

ArticleYear
Dissemination, adoption, and implementation of acamprosate for treating alcohol use disorders.
    Journal of studies on alcohol and drugs, 2014, Volume: 75, Issue:3

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Cross-Sectional Studies; Health Plan Imp

2014
Pain as a predictor of heavy drinking and any drinking lapses in the COMBINE study and the UK Alcohol Treatment Trial.
    Addiction (Abingdon, England), 2015, Volume: 110, Issue:8

    Topics: Acamprosate; Adult; Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Behavior Therap

2015
The effect of acamprosate on alcohol craving and correlation with hypothalamic pituitary adrenal (HPA) axis hormones and beta-endorphin.
    Brain research, 2009, Dec-11, Volume: 1305 Suppl

    Topics: Acamprosate; Adrenocorticotropic Hormone; Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Diso

2009
Does session attendance by a supportive significant other predict outcomes in individual treatment for alcohol use disorders?
    Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:7

    Topics: Acamprosate; Adult; Alcohol-Related Disorders; Alcoholism; Behavior Therapy; Combined Modality Thera

2012
Naltrexone versus acamprosate in the treatment of alcohol dependence: A multi-centre, randomized, double-blind, placebo-controlled trial.
    Addiction (Abingdon, England), 2006, Volume: 101, Issue:10

    Topics: Acamprosate; Adult; Alcohol Deterrents; Alcohol-Related Disorders; Anxiety; Australia; Depressive Di

2006

Other Studies

14 other studies available for taurine and Alcohol-Related Disorders

ArticleYear
More Treatments on Deck for Alcohol Use Disorder.
    JAMA, 2017, Jun-13, Volume: 317, Issue:22

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Amines; Baclofen; Cyclohexanecarboxylic

2017
Review: In alcohol use disorders, acamprosate is more effective for inducing abstinence while naltrexone is more effective for reducing heavy drinking and craving.
    Evidence-based mental health, 2013, Volume: 16, Issue:3

    Topics: Alcohol Deterrents; Alcohol-Related Disorders; Humans; Naltrexone; Narcotic Antagonists; Taurine

2013
Medicaid coverage of medications to treat alcohol and opioid dependence.
    Journal of substance abuse treatment, 2015, Volume: 55

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Buprenorphine, Naloxone Drug Combination

2015
Elevated baseline serum glutamate as a pharmacometabolomic biomarker for acamprosate treatment outcome in alcohol-dependent subjects.
    Translational psychiatry, 2015, Aug-18, Volume: 5

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Biomarkers; Glutamic Acid; Humans; Tauri

2015
The Diffusion of Acamprosate for the Treatment of Alcohol Use Disorder: Results From a National Longitudinal Study.
    Journal of substance abuse treatment, 2016, Volume: 62

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Humans; Insurance Carriers; Longitudinal

2016
Marketing Status and Perceived Efficacy of Drugs for Supporting Abstinence and Reducing Alcohol Intake in Alcohol Use Disorders: A Survey among European Federation of Addiction Societies in Europe.
    European addiction research, 2016, Volume: 22, Issue:6

    Topics: Acamprosate; Alcohol Abstinence; Alcohol Deterrents; Alcohol-Related Disorders; Disulfiram; Europe;

2016
Multifaceted academic detailing program to increase pharmacotherapy for alcohol use disorder: interrupted time series evaluation of effectiveness.
    Addiction science & clinical practice, 2016, 09-15, Volume: 11, Issue:1

    Topics: Acamprosate; Adult; Alcohol Deterrents; Alcohol-Related Disorders; Disulfiram; Female; Fructose; Hum

2016
A Naturalistic Evaluation of Extended-Release Naltrexone in Clinical Practice in Missouri.
    Journal of substance abuse treatment, 2016, Volume: 70

    Topics: Acamprosate; Adult; Alcohol Deterrents; Alcohol-Related Disorders; Delayed-Action Preparations; Fema

2016
Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories.
    Psychopharmacology, 2009, Volume: 205, Issue:3

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Animals; Anisomycin; Behavior, Addictive

2009
Alcohol dependence: after the withdrawal phase. Long-term abstinence: better health and psychosocial status. Psychosocial support for a chronic disorder. Some drugs are useful adjuncts to medical support.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Alcoholics; Alcoholism

2009
The effect of alcohol treatment on social costs of alcohol dependence: results from the COMBINE study.
    Medical care, 2010, Volume: 48, Issue:5

    Topics: Acamprosate; Accidents, Traffic; Alcohol Deterrents; Alcohol-Related Disorders; Behavior Therapy; Co

2010
Pharmacotherapy for adolescent alcohol use disorder.
    CNS drugs, 2012, Jul-01, Volume: 26, Issue:7

    Topics: Acamprosate; Adolescent; Alcohol-Related Disorders; Antidepressive Agents; Attention Deficit Disorde

2012
Alcohol dependence and pharmacologic treatment. Introduction.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Mar-01, Volume: 64, Issue:5 Suppl 3

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Disulfiram; Humans; Naltrexone; Taurine;

2007
Schizophrenia and co-occurring substance use disorder.
    The American journal of psychiatry, 2007, Volume: 164, Issue:3

    Topics: Acamprosate; Adult; Alcohol-Related Disorders; Antipsychotic Agents; Comorbidity; Diagnosis, Dual (P

2007