taurine and Adverse Drug Event studies

Research Excerpts

Excerpt	Relevance	Reference
" For the National Institute on Alcohol Abuse and Alcoholism COMBINE Study, testing the safety and efficacy of naltrexone and acamprosate, both alone and in combination, in the treatment of alcohol dependence, we adapted a standardized instrument--the Systematic Assessment for Treatment Emergent Events (SAFTEE)--for assessing adverse events in these Phase 2- to Phase 3-type studies."	3.73	The COMBINE SAFTEE: a structured instrument for collecting adverse events adapted for clinical studies in the alcoholism field. ( Ait-Daoud, N; Johnson, BA; Roache, JD, 2005)
" Since S-adenosylmethionine (SAMe) is the primary source of the sulfur atom in glutathione, UPLC/MS and NMR were used to evaluate metabolites involved with the transulfuration pathway in urine samples collected during studies of eight liver toxic compounds in Sprague-Dawley rats."	1.35	Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies. ( Beger, RD; Chen, M; Dragan, Y; Holland, RD; Schnackenberg, LK; Sun, J; Tong, W; Welsh, W, 2009)

Research

Studies (6)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Change in Marijuana Use

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	2 (33.33)	2.80

Authors	Studies
Silva Maldonado, P	1
Ramírez Moreno, E	1
Arias Rico, J	1
Fernández Cortés, TL	1
Marino, PF	1
Rossi, GCM	1
Campagna, G	1
Capobianco, D	1
Costagliola, C	1
Schnackenberg, LK	1
Chen, M	1
Sun, J	1
Holland, RD	1
Dragan, Y	1
Tong, W	1
Welsh, W	1
Beger, RD	1
Johnson, BA	1
Ait-Daoud, N	1
Roache, JD	1
Hussar, DA	1
Neher, A	1
Gstöttner, M	1
Nagl, M	1
Scholtz, A	1
Gunkel, AR	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Open-Label Pilot Study of Long-Acting Injectable Naltrexone Treatment for Cannabis Dependence[NCT02088177]	Phase 1/Phase 2	12 participants (Actual)	Interventional	2014-10-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Change in marijuana use, as measured by comparing the mean number of self reported days of marijuana use per week in the final study week, which will be week 8 or earlier if the participant discontinues as compared to the mean number of self reported days of marijuana use in week 1 (NCT02088177)
Timeframe: Weeks 1 - 8

Number of Participants Receiving the Second Injection of Study Medication

Intervention	days (Mean)
Open Label Group	-1.7

The number of participants who accept the second injection at week 5 will be used as one measure of tolerability. (NCT02088177)
Timeframe: Weeks 1 - 5

Article	Year
[Energy drink consumption patterns and its adverse effects on adolescent health.] Revista espanola de salud publica, 2022, Nov-03, Volume: 96 Topics: Adolescent; Adolescent Health; Caffeine; Cross-Sectional Studies; Drug-Related Side Effects and Adve	2022
Effects of Citicoline, Homotaurine, and Vitamin E on Contrast Sensitivity and Visual-Related Quality of Life in Patients with Primary Open-Angle Glaucoma: A Preliminary Study. Molecules (Basel, Switzerland), 2020, Nov-29, Volume: 25, Issue:23 Topics: Administration, Topical; Aged; Aged, 80 and over; Antioxidants; Contrast Sensitivity; Cross-Over Stu	2020
Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies. Toxicology and applied pharmacology, 2009, Feb-15, Volume: 235, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Comet Assay; Creatine; Drug-Related Side Effects an	2009
The COMBINE SAFTEE: a structured instrument for collecting adverse events adapted for clinical studies in the alcoholism field. Journal of studies on alcohol. Supplement, 2005, Issue:15 Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Clinical Trials as Topic; Drug Monitoring; Drug-Related	2005
New drugs 06, part I. Nursing, 2006, Volume: 36, Issue:2 Topics: Acamprosate; Adenine Nucleotides; Alcohol Deterrents; Amyloid; Analgesics, Non-Narcotic; Anti-HIV Ag	2006

taurine and Adverse Drug Event