tariquidar has been researched along with Neoplasms in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Berardi, F; Cantore, M; Colabufo, NA; Contino, M; Inglese, C; Niso, M; Perrone, R | 1 |
| Cai, Z; Ghaleb, H; Huang, W; Jiang, Y; Liu, Y; Qian, H; Qiu, Q; Shi, W; Yin, Z; Zhang, P; Zhou, J; Zou, F | 1 |
| Ambudkar, SV; Lusvarghi, S; Raju, N; Sajid, A; Swenson, RE; Vahedi, S | 1 |
| Boumendjel, A; Di Pietro, A; Gauthier, C; Lecerf-Schmidt, F; Payen, L; Peres, B; Valdameri, G; Winter, E | 1 |
| Balis, FM; Chen, CC; Cole, D; Fox, E; Pastakia, D; Widemann, BC; Yang, SX | 1 |
| Abraham, J; Bakke, S; Balis, F; Bates, SE; Chen, C; Dwyer, A; Edgerly, M; Fojo, T; Goldspiel, B; Robey, R; Rutt, A; Van Tellingen, O; Wilson, R | 1 |
| Aikou, T; Bates, S; Fojo, T; Fok, P; Goldsmith, ME; Kitazono, M | 1 |
| Callaghan, R; Mellor, HR; Modok, S | 1 |
| Bates, SE; Fox, E | 1 |
| Ambudkar, SV; Barnett, D; Bates, SE; Finley, EM; Fojo, T; Oldham, RK; Robey, RW; Shukla, S | 1 |
| Bates, SF; Chen, C; Figg, WD; Fojo, T; Kang, M; Robey, R | 1 |
5 review(s) available for tariquidar and Neoplasms
| Article | Year |
|---|---|
Perspectives of P-glycoprotein modulating agents in oncology and neurodegenerative diseases: pharmaceutical, biological, and diagnostic potentials.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Central Nervous System Agents; Humans; Neoplasms; Neurodegenerative Diseases | 2010 |
ABCG2: recent discovery of potent and highly selective inhibitors.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Chalcones; Chromones; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Neoplasms; Quinolines; Stilbenes | 2013 |
Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancer.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Clinical Trials as Topic; Cyclosporins; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Imidazoles; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms; Quinolines; RNA Interference | 2006 |
Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasms; Protein Transport; Quinolines | 2007 |
Reversal of multidrug resistance: lessons from clinical oncology.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzazepines; Clinical Trials as Topic; Cyclosporins; Dibenzocycloheptenes; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Mice; Mice, Knockout; Neoplasm Proteins; Neoplasms; Piperidines; Pyridines; Quinolines; Radionuclide Imaging; Radiopharmaceuticals; Rhodamines; Technetium Tc 99m Sestamibi; Tissue Distribution; Tumor Cells, Cultured | 2002 |
3 trial(s) available for tariquidar and Neoplasms
| Article | Year |
|---|---|
Pharmacokinetic and pharmacodynamic study of tariquidar (XR9576), a P-glycoprotein inhibitor, in combination with doxorubicin, vinorelbine, or docetaxel in children and adolescents with refractory solid tumors.
Topics: Adolescent; Anemia; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Child; Child, Preschool; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Male; Metabolic Clearance Rate; Neoplasms; Neutropenia; Quinolines; Taxoids; Treatment Outcome; Vinblastine; Vinorelbine; Vomiting | 2015 |
A phase I study of the P-glycoprotein antagonist tariquidar in combination with vinorelbine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Drug Interactions; Humans; Metabolic Clearance Rate; Middle Aged; Neoplasms; Neutropenia; Quinolines; Vinblastine; Vinorelbine; Young Adult | 2009 |
Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).
Topics: Adenosine Triphosphatases; Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Factors; Biological Transport; Cell Line; Cell Line, Tumor; Cyclosporins; Depsipeptides; Fluorescent Dyes; Fluorouracil; Humans; Insecta; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Prazosin; Quinolines; Rhodamine 123; Verapamil; Vinblastine | 2008 |
3 other study(ies) available for tariquidar and Neoplasms
| Article | Year |
|---|---|
Exploration of novel phthalazinone derivatives as potential efflux transporter inhibitors for reversing multidrug resistance and improving the oral absorption of paclitaxel.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel | 2022 |
Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1).
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Azoles; Boron Compounds; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; HeLa Cells; Humans; Inhibitory Concentration 50; Microscopy, Fluorescence; Molecular Docking Simulation; Molecular Imaging; Molecular Probes; Neoplasms; Nitrobenzenes; Quinolines; Recombinant Proteins | 2019 |
The histone deacetylase inhibitor FK228 preferentially enhances adenovirus transgene expression in malignant cells.
Topics: Acetylation; Adenoviruses, Human; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast; Cell Division; Cells, Cultured; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Depsipeptides; Drug Combinations; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Hepatocytes; Histone Deacetylase Inhibitors; Histones; Humans; Integrin alphaV; Kidney; Neoplasms; Peptides, Cyclic; Quinolines; Receptors, Virus; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Transgenes | 2003 |