tanshinone has been researched along with Myocardial Infarction in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 15 (60.00) | 24.3611 |
| 2020's | 7 (28.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X; Wu, C | 1 |
| Dong, Z; Guo, J; Wang, Y; Xing, X; Yan, J; Zhang, G; Zhang, X | 2 |
| Dong, Z; Du, Y; Gong, H; Guo, J; Liu, Y; Lu, Q; Lv, N; Xing, X; Zhao, J | 1 |
| Chen, L; Liu, G; Shi, H; Wei, L; Yu, Q | 1 |
| Liu, X; Lu, Y; Yan, Y | 1 |
| Chen, R; Chen, W; Huang, X; Rui, Q | 1 |
| Ai, W; Chen, S; Duan, C; Fang, H; Fang, Y; Jiang, B; Liu, Z; Wang, L; Xie, P | 1 |
| Han, XR; Li, L; Lu, J; Wang, YJ; Wen, X; Wu, DM; Xu, L; Zheng, YL | 1 |
| Hu, S; Li, J; Wu, F; Zhang, S; Zhang, X | 1 |
| Chen, P; Guo, R; Lan, Y; Mao, S; Wang, L; Zhang, M | 1 |
| Du, H; Hou, J; Wang, C; Wang, Y; Yan, S; Yang, J; Zhang, X; Zhao, H; Zhu, L | 1 |
| A, S; Chen, J; Fan, G; Gao, X; Han, X; Jia, H; Li, M; Liang, W; Liu, W; Mao, J; Shang, Y; Tan, B; Wang, W; Xu, Q; Zhang, J; Zou, Y | 1 |
| Chen, X; Guo, D; Li, C; Shao, M; Wang, Q; Wang, W; Wang, X; Wang, Y; Wu, Y; Zhang, Q; Zhang, X | 1 |
| Hinek, A; Mao, S; Wang, Y; Zhang, M | 1 |
| Li, H; Li, P; Li, S; Shi, Q; Yang, F; Zhao, L | 1 |
| Wu, LM; Xu, W; Yang, J | 1 |
| Cai, B; Chu, W; Li, B; Li, X; Lu, Y; Pan, Z; Qiao, G; Shan, H; Xu, C; Yang, B; Zhang, L; Zhang, Y | 1 |
| Chen, Y; Ma, J; Ren, ZH; Tong, YH; Xu, W | 1 |
| Cao, F; Du, J; Gao, H; Li, Y; Sun, D; Wang, H; Wei, L; Zhang, Y; Zhao, L | 1 |
| Chen, Y; Han, H; Hong, D; Qiao, H; Tong, Y; Wu, Y; Xu, W; Yang, J; Zhou, C | 1 |
| Chu, W; Li, B; Li, X; Lu, Y; Shan, H; Wang, B; Yang, B; Zhang, J; Zhang, L; Zhang, Y; Zhao, M | 1 |
| Chen, M; Huo, Y; Li, J; Lou, L; Pan, C; Singh, G; Wang, S; Wu, A; Zhang, D; Zhao, M | 1 |
| Fan, G; Gao, X; Hu, L; Jiang, M; Li, X; Wang, X; Wang, Y; Zhu, Y | 1 |
| Li, XH; Tang, RY | 1 |
1 trial(s) available for tanshinone and Myocardial Infarction
| Article | Year |
|---|---|
Effects of alprostadil combined with tanshinone IIa injection on microcirculation disorder, outcomes, and cardiac function in AMI patients after PCI.
Topics: Abietanes; Alprostadil; Humans; Microcirculation; Myocardial Infarction; Percutaneous Coronary Intervention; Stroke Volume; Ventricular Function, Left | 2021 |
24 other study(ies) available for tanshinone and Myocardial Infarction
| Article | Year |
|---|---|
Tanshinone IIA improves cardiac function via regulating miR-499-5p dependent angiogenesis in myocardial ischemic mice.
Topics: Abietanes; Animals; Cardiovascular Agents; Disease Models, Animal; Mice; Mice, Inbred C57BL; MicroRNAs; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Neovascularization, Pathologic; Neovascularization, Physiologic; PTEN Phosphohydrolase | 2022 |
Acute myocardial infarction therapy using calycosin and tanshinone co-loaded; mitochondrion-targeted tetrapeptide and cyclic arginyl-glycyl-aspartic acid peptide co-modified lipid-polymer hybrid nano-system: preparation, characterization, and anti myocard
Topics: Abietanes; Animals; Isoflavones; Lipids; Mitochondria; Myocardial Infarction; Nanoparticles; Oligopeptides; Peptides, Cyclic; Polymers; Rats | 2022 |
Acute myocardial infarction therapy using calycosin and tanshinone co-loaded mitochondria targeted lipid-polymer hybrid nano-system: Preparation, characterization, and anti myocardial infarction activity assessment.
Topics: Abietanes; Animals; Cardiotonic Agents; Drug Delivery Systems; Isoflavones; Lipids; Mitochondria; Myocardial Infarction; Polymers; Rats; Rats, Sprague-Dawley | 2022 |
Therapy for myocardial infarction: In vitro and in vivo evaluation of puerarin-prodrug and tanshinone co-loaded lipid nanoparticulate system.
Topics: Abietanes; Animals; Drug Carriers; Drug Delivery Systems; Heart; Humans; Isoflavones; Lipids; Male; Myocardial Infarction; Nanoparticles; Particle Size; Polyethylene Glycols; Prodrugs; Rats; Rats, Sprague-Dawley | 2019 |
Tanshinone IIA alleviates hypoxia/reoxygenation induced cardiomyocyte injury via lncRNA AK003290/miR-124-5p signaling.
Topics: Abietanes; Animals; Apoptosis; Cell Hypoxia; Cell Line; Disease Models, Animal; L-Lactate Dehydrogenase; Malate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; MicroRNAs; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Rats; Reactive Oxygen Species; RNA, Long Noncoding; Signal Transduction | 2020 |
Tanshinone IIA attenuates heart failure via inhibiting oxidative stress in myocardial infarction rats.
Topics: Abietanes; Actins; Animals; Antioxidants; Collagen; Fibrosis; Heart Failure; Male; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardium; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta | 2021 |
Tanshinone‑IIA inhibits myocardial infarct via decreasing of the mitochondrial apoptotic signaling pathway in myocardiocytes.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Calcium; Cardiotonic Agents; Caspase 3; Cell Survival; Cells, Cultured; Male; Myocardial Infarction; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Tanshinone IIA prevents left ventricular remodelling via the TLR4/MyD88/NF-κB signalling pathway in rats with myocardial infarction.
Topics: Abietanes; Animals; Apoptosis; Disease Models, Animal; Gene Expression Regulation; Humans; Macrophages; Myeloid Differentiation Factor 88; Myocardial Infarction; Myocytes, Cardiac; NF-kappa B; Rats; Signal Transduction; Toll-Like Receptor 4; Transcription Factor RelA; Ventricular Remodeling | 2018 |
Triphenylphosphonium and D-α-tocopheryl polyethylene glycol 1000 succinate-modified, tanshinone IIA-loaded lipid-polymeric nanocarriers for the targeted therapy of myocardial infarction.
Topics: Abietanes; Animals; Cell Death; Cell Survival; Drug Carriers; Drug Liberation; Endocytosis; Lipids; Molecular Targeted Therapy; Myocardial Infarction; Nanoparticles; Onium Compounds; Organophosphorus Compounds; Particle Size; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Static Electricity; Tissue Distribution; Vitamin E | 2018 |
Nanoparticle-mediated delivery of Tanshinone IIA reduces adverse cardiac remodeling following myocardial infarctions in a mice model: role of NF-κB pathway.
Topics: Abietanes; Animals; Disease Models, Animal; Drug Delivery Systems; Humans; Mice; Myocardial Infarction; Nanoparticles; NF-kappa B; Signal Transduction; Ventricular Remodeling | 2018 |
Anti-depressive effect of Shuangxinfang on rats with acute myocardial infarction: Promoting bone marrow mesenchymal stem cells mobilization and alleviating inflammatory response.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Cell Movement; Cells, Cultured; Male; Mesenchymal Stem Cells; Myocardial Infarction; Random Allocation; Rats; Rats, Sprague-Dawley; Saponins | 2019 |
Rebuilding Postinfarcted Cardiac Functions by Injecting TIIA@PDA Nanoparticle-Cross-linked ROS-Sensitive Hydrogels.
Topics: Abietanes; Animals; Heart; Humans; Hyaluronic Acid; Hydrogels; Indoles; Inflammation; Interleukin-1beta; Interleukin-6; Magnetic Resonance Imaging; Myocardial Infarction; Nanoparticles; Polymers; Rabbits; Reactive Oxygen Species; Tissue Engineering; Tumor Necrosis Factor-alpha | 2019 |
Tanshinone IIA protects against heart failure post-myocardial infarction via AMPKs/mTOR-dependent autophagy pathway.
Topics: Abietanes; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Cardiotonic Agents; Heart Failure; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley | 2019 |
Phytoestrogen, tanshinone IIA diminishes collagen deposition and stimulates new elastogenesis in cultures of human cardiac fibroblasts.
Topics: Abietanes; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Collagen Type I; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Elastic Tissue; Elastin; Enzyme Activation; Extracellular Matrix; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Phosphorylation; Phytoestrogens; Protein Binding; Protein-Lysine 6-Oxidase; Receptors, Estrogen; Receptors, G-Protein-Coupled; Tropoelastin; Up-Regulation | 2014 |
microRNA-29b Mediates the Antifibrotic Effect of Tanshinone IIA in Postinfarct Cardiac Remodeling.
Topics: Abietanes; Animals; Cells, Cultured; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Fibrosis; Male; MicroRNAs; Myocardial Infarction; Myocardium; Rats, Sprague-Dawley; Recovery of Function; RNA Interference; Smad3 Protein; Transfection; Transforming Growth Factor beta1; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling | 2015 |
Cardioprotective effects of tanshinone IIA on myocardial ischemia injury in rats.
Topics: Abietanes; Animals; Antioxidants; Cardiotonic Agents; Heart; Hemodynamics; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Male; Myocardial Infarction; Myocardium; Phenanthrenes; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Vascular Endothelial Growth Factor A | 2009 |
Tanshinone IIA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1.
Topics: Abietanes; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Down-Regulation; Drugs, Chinese Herbal; Electrocardiography; In Vitro Techniques; Male; MicroRNAs; Myocardial Infarction; Myocytes, Cardiac; Patch-Clamp Techniques; Phenanthrenes; Potassium Channels, Inwardly Rectifying; Quinidine; Rats; Rats, Wistar; Serum Response Factor | 2009 |
Tanshinone II A attenuates inflammatory responses of rats with myocardial infarction by reducing MCP-1 expression.
Topics: Abietanes; Animals; Anti-Inflammatory Agents; Chemokine CCL2; Coronary Vessels; Disease Models, Animal; Drugs, Chinese Herbal; Fibroblasts; Heart; Inflammation; Macrophages; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NF-kappa B; Phenanthrenes; Phytotherapy; Plant Roots; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2010 |
Tanshinone IIA pretreatment protects myocardium against ischaemia/reperfusion injury through the phosphatidylinositol 3-kinase/Akt-dependent pathway in diabetic rats.
Topics: Abietanes; Androstadienes; Animals; Anticoagulants; Apoptosis; Blotting, Western; Diabetes Mellitus, Experimental; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phenanthrenes; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Wortmannin | 2010 |
Tanshinone IIA increases recruitment of bone marrow mesenchymal stem cells to infarct region via up-regulating stromal cell-derived factor-1/CXC chemokine receptor 4 axis in a myocardial ischemia model.
Topics: Abietanes; Animals; Benzylamines; Bone Marrow Cells; Cell Movement; Chemokine CXCL12; Cyclams; Disease Models, Animal; Drugs, Chinese Herbal; Female; Heterocyclic Compounds; Male; Mesenchymal Stem Cells; Myocardial Infarction; Myocardial Ischemia; Myocardium; Phytotherapy; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Salvia miltiorrhiza; Stem Cell Transplantation; Up-Regulation | 2011 |
Tanshinone IIA inhibits miR-1 expression through p38 MAPK signal pathway in post-infarction rat cardiomyocytes.
Topics: Abietanes; Animals; Connexin 43; Imidazoles; MicroRNAs; Myocardial Infarction; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Wistar; Serum Response Factor; Signal Transduction | 2010 |
Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways.
Topics: Abietanes; Amino Acid Transport Systems, Basic; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Arginine; Benzofurans; Cardiovascular Agents; Cationic Amino Acid Transporter 1; Cells, Cultured; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Time Factors; Vasodilation | 2011 |
Differential cardioprotective effects of salvianolic acid and tanshinone on acute myocardial infarction are mediated by unique signaling pathways.
Topics: Abietanes; Animals; Apoptosis; Caffeic Acids; Calcium; Cardiovascular Agents; Cell Adhesion; Complement Pathway, Alternative; Disease Models, Animal; Drugs, Chinese Herbal; Estrogens; Gene Expression Regulation; Heart; Lactates; Male; Microarray Analysis; Myocardial Infarction; Oxidative Stress; Phenanthrolines; Phytotherapy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Salvia miltiorrhiza; Selective Estrogen Receptor Modulators; Signal Transduction; Systole | 2011 |
[Relationship between inhibitory action of tanshinone on neutrophil function and its prophylactic effects on myocardial infarction].
Topics: Abietanes; Acid Phosphatase; Adhesiveness; Animals; Dose-Response Relationship, Drug; Female; Male; Myocardial Infarction; Myocardium; Neutrophils; Phagocytosis; Phenanthrenes; Rabbits | 1991 |