tanshinone has been researched along with Infarction, Middle Cerebral Artery in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, C | 1 |
| Du, S; Liu, L; Miao, Q; Sun, X; Wang, R | 1 |
| Huang, LH; Li, WW; Wang, F; Wen, PY; Yang, FZ; Zhou, J; Zhou, L | 1 |
| Bondy, SC; Ding, ZG; Hu, Y; Li, WW; Luo, H; Tian, Y; Wang, F; Wang, JG; Wen, PY; Yang, FZ; Zhou, J; Zhou, L | 1 |
| Bondy, SC; Jian, L; Li, W; Luo, H; Wen, P; Yang, F; Zhou, J; Zhou, L | 1 |
| Li, J; Li, WW; Liu, J; Lu, BL; Luo, H; Wen, PY; Yang, FZ; Zhou, J; Zhou, L | 1 |
| Dong, K; Qiao, H; Wu, L; Xu, W; Yang, J | 1 |
| Bai, C; Fu, R; Tang, C; Wu, A; Xue, H | 1 |
| Chen, WY; Huang, M; Liu, FY; Sun, CM; Wang, HM; Zhu, BD; Zhu, GX | 1 |
| Chen, Y; Fauzee, NJ; Li, L; Wu, J; Wu, X; Yu, S; Zhao, J; Zhao, Y | 1 |
| Han, R; Li, J; Luo, Q; Shen, J; Tang, Q; Xiao, H | 1 |
| Chan, E; Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Sheu, FS; Wen, JY; Yu, XQ; Yu, XY; Zhou, SF; Zhou, ZW | 1 |
| Chen, X; Li, XX; Xue, CC; Zhou, SF; Zhou, ZW | 1 |
13 other study(ies) available for tanshinone and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Improvement effects of tanshinone on the impaired cognition and motor function in MCAO mice with ischemic penumbra.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cognition; Escape Reaction; Grooming; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Ischemic Stroke; Mice; Microglia; Motor Activity; Movement; Neurons; Neuroprotective Agents | 2021 |
Combination of puerarin and tanshinone IIA alleviates ischaemic stroke injury in rats
Topics: Abietanes; Animals; Brain Injuries; Brain Ischemia; Infarction, Middle Cerebral Artery; Ischemic Stroke; Isoflavones; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Rats; S100 Calcium Binding Protein beta Subunit | 2022 |
[Study on regulation of tanshinone II(A) on GFAP and ATPase and PDI of cerebral ischemia reperfusion injury in rats].
Topics: Abietanes; Adenosine Triphosphatases; Animals; Brain; Brain Ischemia; Disease Models, Animal; Glial Fibrillary Acidic Protein; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Protein Disulfide-Isomerases; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rhizome; Salvia miltiorrhiza | 2012 |
Protective effect of Tanshinone IIA against infarct size and increased HMGB1, NFκB, GFAP and apoptosis consequent to transient middle cerebral artery occlusion.
Topics: Abietanes; Animals; Blotting, Western; Cerebral Infarction; Glial Fibrillary Acidic Protein; HMGB1 Protein; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; NF-kappa B; Rats; Rats, Sprague-Dawley | 2014 |
Tanshinone IIA attenuates the cerebral ischemic injury-induced increase in levels of GFAP and of caspases-3 and -8.
Topics: Abietanes; Animals; Blotting, Western; Brain Ischemia; Caspase 3; Caspase 8; Cell Death; Disease Models, Animal; Entorhinal Cortex; Glial Fibrillary Acidic Protein; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley | 2015 |
Tanshinone IIA increases levels of NeuN, protein disulfide isomerase, and Na+/K+-ATPase and decreases evidence of microglial activation after cerebral ischemic injury.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; CD11b Antigen; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Nervous System Diseases; Phosphopyruvate Hydratase; Protein Disulfide-Isomerases; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2016 |
Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice.
Topics: Abietanes; Animals; Astrocytes; Brain; Brain Ischemia; Cells, Cultured; Cerebral Infarction; Drugs, Chinese Herbal; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Phenanthrenes; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2009 |
The effects of Tanshinone IIA on blood-brain barrier and brain edema after transient middle cerebral artery occlusion in rats.
Topics: Abietanes; Animals; Blood-Brain Barrier; Brain; Edema; Evans Blue; Infarction, Middle Cerebral Artery; Intercellular Adhesion Molecule-1; Ischemic Attack, Transient; Matrix Metalloproteinase 9; Membrane Proteins; Occludin; Permeability; Phenanthrenes; Phytotherapy; Plant Extracts; Plant Roots; Rats; Reperfusion Injury; Salvia miltiorrhiza; Tight Junctions; Water | 2010 |
[Effect of tanshinone IIA pretreatment on IL-1β and RelA mRNA expression in rats with focal cerebral ischemia].
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Brain Ischemia; Infarction, Middle Cerebral Artery; Interleukin-1beta; Male; Rats; Reperfusion Injury; RNA, Messenger; Transcription Factor RelA | 2010 |
Neuroprotective capabilities of Tanshinone IIA against cerebral ischemia/reperfusion injury via anti-apoptotic pathway in rats.
Topics: Abietanes; Animals; Apoptosis; Caspase 3; DNA Fragmentation; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2012 |
Neuroprotective effects of tanshinone IIA and/or tetramethylpyrazine in cerebral ischemic injury in vivo and in vitro.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Brain Ischemia; Calcium; Cerebral Cortex; Disease Models, Animal; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2012 |
Tanshinone IIB, a primary active constituent from Salvia miltiorrhza, exhibits neuro-protective activity in experimentally stroked rats.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain; Brain Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Phenanthrenes; Plant Extracts; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Stroke; Treatment Outcome | 2007 |
Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier.
Topics: Abietanes; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cells, Cultured; Endothelial Cells; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; Phenanthrenes; Plant Roots; Quinidine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Verapamil | 2007 |