Page last updated: 2024-09-02

tanshinone and Hypoxia

tanshinone has been researched along with Hypoxia in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's9 (69.23)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Cui, Y; Du, X; Gao, M; Hou, Y; Li, Z; Tian, Z; Wang, J; Xu, J1
Chen, X; Dong, P; Jiang, TT; Li, JM; Li, XQ; Liu, YY; Wu, SH; Wu, XJ; Yan, Y; Zhu, JJ1
Liu, Q; Liu, Y; Wang, D; Wang, Y; Yan, X; Zhang, T; Zhao, Z; Zhong, G1
Chang, Y; Chen, L; Guo, QH; Guo, YJ; Ji, ES; Wang, N; Zhao, YS1
Jiang, W; Liu, BL; Liu, J; Qi, LW; Wang, F; Zhao, YP; Zhou, W1
Fan, R; Gao, W; Guo, Y; Mu, S; Qin, G; Sun, Y; Wang, B; Wu, L; Xu, Z; Zhang, Z1
Dong, H; Dong, M; Li, Z; Liu, M; Liu, Y; Luo, Y; Niu, W; Wei, M; Yan, Z; Zhao, P; Zheng, L1
Li, JX; Miao, ZH; Wang, Y; Wang, YQ1
Dong, MQ; Gao, YQ; Li, ZC; Liu, LL; Liu, ML; Luo, Y; Wang, J; Xu, DQ; Xu, M; Zhang, B; Zhao, PT1
Feng, J; Li, CH; Liu, HL; Lou, JN; Peng, L; Ye, LY; Zhang, WJ; Zhou, R1
Bi, Z; Cai, B; Lu, Y; Shan, H; Yang, L; Yin, L; Zhang, B; Zhang, L1
Chan, WY; Chik, KW; Fok, TF; Fung, KP; Gu, GJ; Li, K; Ng, HK; Ng, PC; Wang, CC; Woo, KS; Xia, WJ; Yang, M1
Fujimoto, K; Hirai, K; Kawaguchi, K; Ogawa, M; Takeo, S; Tanonaka, K; Yagi, A1

Other Studies

13 other study(ies) available for tanshinone and Hypoxia

ArticleYear
Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis.
    Journal of ethnopharmacology, 2023, Dec-05, Volume: 317

    Topics: Animals; Atherosclerosis; Hypoxia; Interleukin-1beta; Mice; Molecular Docking Simulation; Plaque, Atherosclerotic; Succinates; Succinic Acid

2023
Tanshinone IIA Suppresses Hypoxia-induced Apoptosis in Medial Vestibular Nucleus Cells
    Current pharmaceutical design, 2020, Volume: 26, Issue:33

    Topics: Abietanes; Apoptosis; Humans; Hypoxia; Vestibular Nuclei

2020
Compatibility of Tanshinone IIA and Astragaloside IV in attenuating hypoxia-induced cardiomyocytes injury.
    Journal of ethnopharmacology, 2017, May-23, Volume: 204

    Topics: Abietanes; Animals; Apoptosis; Cell Line; Cell Movement; Cell Survival; Cells, Cultured; Chemokines; Hypoxia; L-Lactate Dehydrogenase; Macrophages, Peritoneal; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Rats; RNA, Messenger; Saponins; Triterpenes

2017
Tanshinone IIA protects against chronic intermittent hypoxia-induced myocardial injury via activating the endothelin 1 pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Abietanes; Animals; Apoptosis; Blood Pressure; Cardiotonic Agents; Chronic Disease; Electrocardiography; Endothelin-1; Heart Function Tests; Hemodynamics; Hypoxia; Male; Myocardium; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Systole

2017
A mitochondrion-targeting tanshinone IIA derivative attenuates myocardial hypoxia reoxygenation injury through a SDH-dependent antioxidant mechanism.
    Journal of drug targeting, 2019, Volume: 27, Issue:8

    Topics: Abietanes; Animals; Antioxidants; Cells, Cultured; Hypoxia; Mitochondria; Myocardial Ischemia; Rats; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Succinate Dehydrogenase

2019
Tanshinone IIA pretreatment protects free flaps against hypoxic injury by upregulating stem cell-related biomarkers in epithelial skin cells.
    BMC complementary and alternative medicine, 2014, Sep-04, Volume: 14

    Topics: Abietanes; Animals; beta Catenin; Biomarkers; Cell Line, Tumor; Epithelial Cells; Free Tissue Flaps; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hypoxia; Male; Mice; Mice, Inbred BALB C; Phosphorylation; Signal Transduction; Skin; Skin Transplantation; Stem Cells; Up-Regulation; Vascular Endothelial Growth Factor A

2014
Tanshinone IIA attenuates hypoxic pulmonary hypertension via modulating KV currents.
    Respiratory physiology & neurobiology, 2015, Jan-01, Volume: 205

    Topics: Abietanes; Animals; Blotting, Western; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Pulmonary Artery; Rats; Reverse Transcriptase Polymerase Chain Reaction

2015
Tanshinone I inhibits tumor angiogenesis by reducing Stat3 phosphorylation at Tyr705 and hypoxia-induced HIF-1α accumulation in both endothelial and tumor cells.
    Oncotarget, 2015, Jun-30, Volume: 6, Issue:18

    Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Aorta; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Chickens; Chorioallantoic Membrane; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Neovascularization, Pathologic; Phosphorylation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; STAT3 Transcription Factor; Tumor Cells, Cultured; Tyrosine

2015
Tanshinone IIA modulates pulmonary vascular response to agonist and hypoxia primarily via inhibiting Ca2+ influx and release in normal and hypoxic pulmonary hypertension rats.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: Abietanes; Animals; Calcium; Carbon Monoxide; Endothelium, Vascular; Extracellular Space; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Intracellular Space; Male; Nitric Oxide; Phenanthrenes; Phenylephrine; Potassium; Potassium Channel Blockers; Prostaglandins; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction

2010
Tanshinone IIA protects the human blood-brain barrier model from leukocyte-associated hypoxia-reoxygenation injury.
    European journal of pharmacology, 2010, Dec-01, Volume: 648, Issue:1-3

    Topics: Abietanes; Blood-Brain Barrier; Culture Media, Conditioned; Electric Impedance; Endothelial Cells; Humans; Hypoxia; Leukocytes; Oxygen; Permeability; Phenanthrenes; Reperfusion Injury

2010
Tanshinone IIA prevented brain iron dyshomeostasis in cerebral ischemic rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 27, Issue:1

    Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Brain Ischemia; Cation Transport Proteins; Hypoxia; Iron; Male; Membrane Proteins; Rats; Rats, Wistar; Receptors, Transferrin

2011
Partial neuroprotective effect of pretreatment with tanshinone IIA on neonatal hypoxia-ischemia brain damage.
    Pediatric research, 2005, Volume: 58, Issue:4

    Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Body Temperature; Brain; Brain Diseases; Cell Survival; Dose-Response Relationship, Drug; Free Radicals; Hypoxia; Hypoxia-Ischemia, Brain; In Vitro Techniques; Ischemia; Mitochondria; Models, Chemical; Neurons; Organ Size; Oxygen; Phenanthrenes; Rats; Rats, Sprague-Dawley; Time Factors

2005
Beneficial effect of tan-shen, an extract from the root of Salvia, on post-hypoxic recovery of cardiac contractile force.
    Biochemical pharmacology, 1990, Sep-01, Volume: 40, Issue:5

    Topics: Abietanes; Adenosine Triphosphate; Animals; Calcium; Cardiovascular Agents; Creatine Kinase; Hypoxia; Male; Myocardial Contraction; Myocardial Reperfusion; Phenanthrenes; Phosphates; Rats; Rats, Inbred Strains

1990