Page last updated: 2024-09-02

tanshinone and Cirrhosis

tanshinone has been researched along with Cirrhosis in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.00)29.6817
2010's12 (60.00)24.3611
2020's7 (35.00)2.80

Authors

AuthorsStudies
Wang, X; Xiao, C; Xu, Z; Yan, N; Yang, J1
Fan, X; Hou, Y; Li, F; Piao, J; Sun, J; Wei, Y; Xu, Z; Yao, W; Zheng, H1
Huang, D; Wu, M; Yang, F; Ye, C1
Chen, Z; Feng, H; Gao, H; Peng, C; Tang, S; Xie, C; Yuan, Q; Zhang, Z1
Hu, F; Jiang, Y; Li, M; Li, Q; Shen, C; Yang, J1
Ding, K; He, L; Qian, X; Wang, S; Xu, S; Xu, X; Zhang, L1
Bi, Z; Wang, Y; Zhang, W1
Chen, R; Chen, W; Huang, X; Rui, Q1
Cao, L; Fu, X; Huang, B; Lin, F; Lin, Y; Yang, J1
Huang, L; Zheng, M; Zhou, Y; Zhu, J; Zhu, M; Zou, R1
Han, B; Pang, H; Peng, Z; Yu, T1
Huang, X; Li, Q; Sheng, L; Yang, M; Yu, Q; Zhu, M1
Li, H; Li, P; Li, S; Shi, Q; Yang, F; Zhao, L1
Cheng, X; Huang, RH; Lin, X; Wang, DT; Yang, YJ; Zhang, ZH1
Gong, R; Jiang, C; Jin, B; Shao, Q; Xu, B; Zhang, M1
Hu, XR; Huang, DD; Hung, ZA; Shu, M; Zhang, S1
Tang, J; Zhan, C; Zhou, J1
Chen, JW; Fang, J; Gao, J; Huang, HQ; Liu, PQ; Tang, FT; Wang, P; Xu, SW; Zhou, SG1
Bao, Y; Fang, J; Gao, J; Liu, P; Mou, YG; Pi, R; Wang, P; Wu, X; Zhou, S1
Li, Z; Zhan, C; Zhang, L; Zhou, D1

Reviews

2 review(s) available for tanshinone and Cirrhosis

ArticleYear
Renoprotective Effects of Tanshinone IIA: A Literature Review.
    Molecules (Basel, Switzerland), 2023, Feb-20, Volume: 28, Issue:4

    Topics: Abietanes; Animals; Fibrosis; Humans; Kidney; Kidney Diseases; Plant Extracts

2023
A comprehensive review of tanshinone IIA and its derivatives in fibrosis treatment.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137

    Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Drugs, Chinese Herbal; Fibrosis; Humans; Medicine, Chinese Traditional; Salvia miltiorrhiza; Signal Transduction

2021

Other Studies

18 other study(ies) available for tanshinone and Cirrhosis

ArticleYear
Tanshinone IIA from Salvia miltiorrhiza exerts anti-fibrotic effects on cardiac fibroblasts and rat heart tissues by suppressing the levels of pro-fibrotic factors: The key role of miR-618.
    Journal of food biochemistry, 2022, Volume: 46, Issue:2

    Topics: Abietanes; Animals; Fibroblasts; Fibrosis; Heart; MicroRNAs; Myocardium; Rats; Salvia miltiorrhiza

2022
Hierarchically structured microcapsules for oral delivery of emodin and tanshinone IIA to treat renal fibrosis.
    International journal of pharmaceutics, 2022, Mar-25, Volume: 616

    Topics: Abietanes; Animals; Capsules; Emodin; Fibrosis; Rats

2022
Tanshinone I attenuates fibrosis in fibrotic kidneys through down-regulation of inhibin beta-A.
    BMC complementary medicine and therapies, 2022, Apr-19, Volume: 22, Issue:1

    Topics: Abietanes; Animals; Disease Models, Animal; Down-Regulation; Female; Fibrosis; Humans; Inhibins; Kidney; Kidney Diseases; Male; Mice; Rats; Ureteral Obstruction

2022
Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition via the Akt/mTOR/p70S6K pathway in a murine model of systemic sclerosis.
    International immunopharmacology, 2019, Volume: 77

    Topics: Abietanes; Animals; Bleomycin; Cell Line; Disease Models, Animal; Endothelial Cells; Endothelium; Epithelial-Mesenchymal Transition; Female; Fibrosis; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Salvia miltiorrhiza; Scleroderma, Systemic; Signal Transduction; TOR Serine-Threonine Kinases

2019
Tanshinone IIA Ameliorates Streptozotocin-Induced Diabetic Nephropathy, Partly by Attenuating PERK Pathway-Induced Fibrosis.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Abietanes; Animals; Diabetic Nephropathies; eIF-2 Kinase; Endoplasmic Reticulum Stress; Fibrosis; Hypoglycemic Agents; Male; Protective Agents; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin

2020
Tanshinone IIA attenuates heart failure via inhibiting oxidative stress in myocardial infarction rats.
    Molecular medicine reports, 2021, Volume: 23, Issue:6

    Topics: Abietanes; Actins; Animals; Antioxidants; Collagen; Fibrosis; Heart Failure; Male; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardium; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta

2021
Effects of tanshinone IIA on the regulation of renal proximal tubular fibrosis.
    Molecular medicine reports, 2017, Volume: 15, Issue:6

    Topics: Abietanes; Actins; Cadherins; Cell Line; Epithelial Cells; Fibronectins; Fibrosis; Humans; Kidney Tubules, Proximal; Renal Insufficiency, Chronic; RNA, Messenger; Snail Family Transcription Factors; Vimentin

2017
Tanshinone IIA protects against subclinical lipopolysaccharide induced cardiac fibrosis in mice through inhibition of NADPH oxidase.
    International immunopharmacology, 2018, Volume: 60

    Topics: Abietanes; Acetophenones; Animals; Cardiomyopathies; Fibrosis; Lipopolysaccharides; Male; Mice, Inbred C57BL; Myocardium; NADPH Oxidase 2; Phosphoproteins; Protective Agents; Reactive Oxygen Species

2018
The complex regulation of tanshinone IIA in rats with hypertension-induced left ventricular hypertrophy.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Abietanes; Animals; Apelin; Apelin Receptors; Apoptosis; Blood Pressure; Collagen; Fibrosis; Heart Function Tests; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Intercellular Signaling Peptides and Proteins; Male; Malondialdehyde; Matrix Metalloproteinase 2; Myocytes, Cardiac; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Superoxide Dismutase; Systole; Tissue Inhibitor of Metalloproteinase-2; Ultrasonography; Ventricular Remodeling

2014
Tanshinon IIA injection accelerates tissue expansion by reducing the formation of the fibrous capsule.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Abietanes; Animals; Apoptosis; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Fibrosis; Immunosuppressive Agents; Injections, Intraperitoneal; Macrophages; Male; Neovascularization, Physiologic; Rats, Sprague-Dawley; Skin; Tissue Expansion

2014
microRNA-29b Mediates the Antifibrotic Effect of Tanshinone IIA in Postinfarct Cardiac Remodeling.
    Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:5

    Topics: Abietanes; Animals; Cells, Cultured; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Fibrosis; Male; MicroRNAs; Myocardial Infarction; Myocardium; Rats, Sprague-Dawley; Recovery of Function; RNA Interference; Smad3 Protein; Transfection; Transforming Growth Factor beta1; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling

2015
Tanshinone IIA attenuates renal fibrosis and inflammation via altering expression of TGF-β/Smad and NF-κB signaling pathway in 5/6 nephrectomized rats.
    International immunopharmacology, 2015, Volume: 26, Issue:1

    Topics: Abietanes; Animals; Blotting, Western; Disease Models, Animal; Drugs, Chinese Herbal; Fibrosis; Gene Expression; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Medicine, Chinese Traditional; Nephrectomy; NF-kappa B; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Renal Insufficiency, Chronic; Signal Transduction; Smad Proteins; Transforming Growth Factor beta

2015
Tanshinone IIA Attenuates Renal Fibrosis after Acute Kidney Injury in a Mouse Model through Inhibition of Fibrocytes Recruitment.
    BioMed research international, 2015, Volume: 2015

    Topics: Abietanes; Acute Kidney Injury; Animals; Fibrosis; Folic Acid; Kidney; Mice; Mice, Inbred C57BL

2015
Effects of tanshinone IIA on fibrosis in a rat model of cirrhosis through heme oxygenase-1, inflammation, oxidative stress and apoptosis.
    Molecular medicine reports, 2016, Volume: 13, Issue:4

    Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biomarkers; Cytokines; Disease Models, Animal; Fibrosis; Heme Oxygenase-1; Inflammation; Inflammation Mediators; Male; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Rats

2016
Effects of tanshinone IIA on transforming growth factor beta1-Smads signal pathway in renal interstitial fibroblasts of rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2008, Volume: 28, Issue:5

    Topics: Abietanes; Animals; Cells, Cultured; Fibroblasts; Fibronectins; Fibrosis; Kidney; Phenanthrenes; Rats; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1

2008
Tanshinone II-A attenuates cardiac fibrosis and modulates collagen metabolism in rats with renovascular hypertension.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Dec-15, Volume: 18, Issue:1

    Topics: Abietanes; Animals; Blood Pressure; Cardiovascular Agents; Collagen; Drugs, Chinese Herbal; Fibrosis; Gene Expression; Heart; Hypertension, Renovascular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Phytotherapy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Salvia miltiorrhiza; Tetrazoles; Tissue Inhibitor of Metalloproteinase-1; Valine; Valsartan

2010
Tanshinone IIA prevents cardiac remodeling through attenuating NAD (P)H oxidase-derived reactive oxygen species production in hypertensive rats.
    Die Pharmazie, 2011, Volume: 66, Issue:7

    Topics: Abietanes; Animals; Blotting, Western; Cardiomegaly; Cardiotonic Agents; Coronary Circulation; Enzyme Inhibitors; Fibrosis; Heart Diseases; Hemodynamics; Hypertension, Renovascular; Male; Myocardium; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Stroke Volume; Ultrasonography; Ventricular Dysfunction, Left

2011
Inhibitory effect of tanshinone II A on TGF II-β1-induced cardiac fibrosis.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2012, Volume: 32, Issue:6

    Topics: Abietanes; Animals; Fibrosis; Heart; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1

2012