tanshinone has been researched along with Cancer of Liver in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 17 (56.67) | 24.3611 |
| 2020's | 5 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, C; Cai, S; Chen, J; Hong, X; Li, D; Li, J; Li, P; Lin, E; Wang, B; Yin, Z; Zeng, G; Zhang, M; Zhao, J; Zou, B | 1 |
| Feng, N; Geng, A; Qian, Z | 1 |
| Cai, F; Jiang, H; Li, Y; Ma, L; Niu, Y; Tao, Y; Wang, X; Wang, Z; Xu, X; Yu, Y; Zhang, C; Zhang, X | 1 |
| An, C; Cheng, S; Li, S; Liu, G; Pang, B; Sun, S; Wang, J; Zhang, G; Zhang, Y; Zheng, L | 1 |
| Liu, J; Liu, X | 1 |
| Bi, F; Tie, M; Wang, K; Zhang, Y | 1 |
| Deng, L; Hu, H; Hu, J; Hu, X; Zhang, J; Zheng, G | 1 |
| Dong, BS; Shi, MJ; Su, SB; Yang, WN; Zhang, H | 1 |
| Chen, M; Fang, X; Li, Y; Wang, Y; Zhang, J; Zhou, D | 1 |
| Chen, CY; Li, WC; Ting, CT; Tsai, TH | 1 |
| Cai, J; Costanza, F; Fan, Z; Ji, G; Li, Q; Song, D; Wang, Y | 1 |
| Chang, W; Han, HJ; Hwang, GH; Jeon, YJ; Kim, JS; Kim, LK; Lee, MY; Lee, YM; Liu, KH; Park, SH; Wu, Z | 1 |
| Chen, F; Chen, M; Fang, X; He, Y; Wang, Y; Zhang, J | 1 |
| Chai, H; Ding, L; Dou, X; Hu, L; Ren, X; Tang, L; Wang, C; Xia, Y; Xie, B | 1 |
| Chen, JH; Han, M; He, SX; Hou, HL; Ren, MD; Wang, ZL; Zhai, XM | 1 |
| Lee, WY; Liu, KW; Yeung, JH | 1 |
| Cheng, CY; Su, CC | 1 |
| Cai, Z; Long, X; Yang, P; Yao, J; Zhang, J; Zhang, Y | 1 |
| Dai, ZK; Huang, JE; Luo, Y; Qin, JK; Xu, Q; Zhao, HL | 1 |
| Chen, DR; Chen, YL; Cheng, CY; Chien, SY; Kuo, SJ; Su, CC | 1 |
| Chu, T; Jin, H; Li, H; Ma, WC; Mao, SJ; Zhang, N; Zhang, Q | 1 |
| Fan, Q; Ma, H; Xin, J; Yu, J; Zhang, C | 2 |
| Chai, ZT; Fu, YL; Kong, LQ; Liu, L; Lu, L; Ren, ZG; Sun, HC; Tang, ZY; Wang, WQ; Xu, HX; Zhang, QB; Zhu, XD | 1 |
| Fu, LB; Tang, Y; Tang, ZZ | 1 |
| Fu, L; Tang, Y; Tang, Z | 1 |
| Li, SF; Wang, XJ; Wei, YQ; Xiao, F; Yuan, SL; Zhang, J | 1 |
| Chen, WG; Li, QX; Liu, YH; Qiu, Y; Zhong, ZH | 1 |
| Chiu, LC; Lee, WY; Yeung, JH | 1 |
| Huang, R; Song, Y; Wang, X; Yuan, S | 1 |
2 review(s) available for tanshinone and Cancer of Liver
| Article | Year |
|---|---|
Preventive and therapeutic role of Tanshinone ⅡA in hepatology.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Humans; Liver Diseases; Liver Neoplasms; Plant Extracts | 2019 |
Preventive and therapeutic role of traditional Chinese herbal medicine in hepatocellular carcinoma.
Topics: Abietanes; Benzylisoquinolines; Berberine; Carcinoma, Hepatocellular; Curcumin; Drugs, Chinese Herbal; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Resveratrol; Scutellaria baicalensis; Stilbenes | 2015 |
28 other study(ies) available for tanshinone and Cancer of Liver
| Article | Year |
|---|---|
Combined Treatment of Tanshinone I and Epirubicin Revealed Enhanced Inhibition of Hepatocellular Carcinoma by Targeting PI3K/AKT/HIF-1α.
Topics: Abietanes; Actins; Animals; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Epirubicin; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2022 |
Tanshinone I suppresses hepatocellular carcinoma cells growth through targeting DNA double-strand break repair.
Topics: Carcinoma, Hepatocellular; DNA; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA Repair; Humans; Liver Neoplasms; Recombinational DNA Repair | 2023 |
Tanshinone IIA mediates SMAD7-YAP interaction to inhibit liver cancer growth by inactivating the transforming growth factor beta signaling pathway.
Topics: Abietanes; Adaptor Proteins, Signal Transducing; Adult; Aged; Antineoplastic Agents, Phytogenic; Carcinogenesis; Cell Line, Tumor; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Female; Humans; Liver Neoplasms; Male; Middle Aged; Phytotherapy; Salvia miltiorrhiza; Smad7 Protein; Transcription Factors; Transforming Growth Factor beta; YAP-Signaling Proteins | 2019 |
Tanshinone I regulates autophagic signaling via the activation of AMP-activated protein kinase in cancer cells.
Topics: Abietanes; AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Breast Neoplasms; Cell Proliferation; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Signal Transduction; Tumor Cells, Cultured | 2020 |
Tanshinone I induces cell apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing p53/DRAM-mediated autophagy in human hepatocellular carcinoma.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Cell Proliferation; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Liver Neoplasms; Membrane Proteins; Reactive Oxygen Species; Tumor Suppressor Protein p53 | 2020 |
Tanshinone II improves distribution and anti-tumor efficacy of pegylated liposomal doxorubicin via normalizing the structure and function of tumor vasculature in hepa1-6 hepatoma mice model.
Topics: Abietanes; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Disease Models, Animal; Doxorubicin; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Mice; Mice, Inbred C57BL; Microvessels; Polyethylene Glycols | 2018 |
Galactose-Modified PH-Sensitive Niosomes for Controlled Release and Hepatocellular Carcinoma Target Delivery of Tanshinone IIA.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Galactose; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Liposomes; Liver Neoplasms; Male; Mice; Random Allocation; Rats; Rats, Sprague-Dawley | 2021 |
TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Carcinoma, Hepatocellular; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Male; Micelles; Poloxamer; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Serum Albumin, Bovine; Vitamin E | 2014 |
Targeted delivery of tanshinone IIA-conjugated mPEG-PLGA-PLL-cRGD nanoparticles to hepatocellular carcinoma.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Survival; Diffusion; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Nanocapsules; Oligopeptides; Polyesters; Polyethylene Glycols; Polylysine; Treatment Outcome | 2014 |
Inhibition of cytochrome P450 2J2 by tanshinone IIA induces apoptotic cell death in hepatocellular carcinoma HepG2 cells.
Topics: Abietanes; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Astemizole; Carcinoma, Hepatocellular; Cell Survival; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Dose-Response Relationship, Drug; Female; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Species Specificity; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Glycyrrhetinic acid-decorated and reduction-sensitive micelles to enhance the bioavailability and anti-hepatocellular carcinoma efficacy of tanshinone IIA.
Topics: Abietanes; Animals; Biological Availability; Carcinoma, Hepatocellular; Cell Line, Tumor; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Glycyrrhetinic Acid; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Mice; Micelles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Succinimides | 2016 |
Tanshinone IIA induced cell death via miR30b-p53-PTPN11/SHP2 signaling pathway in human hepatocellular carcinoma cells.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Hep G2 Cells; Humans; Kinetics; Liver Neoplasms; MicroRNAs; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Signal Transduction; Transcription Factors; Tumor Suppressor Protein p53 | 2017 |
[Effect of Tanshinone II A on expression of EGF and EGFR in hepatocellular carcinoma cell line SMMC-7721].
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Humans; Liver Neoplasms; Phenanthrenes | 2009 |
Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells.
Topics: Abietanes; Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Activation; Furans; Humans; Imidazoles; Inhibitory Concentration 50; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Liver Neoplasms; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Protein Transport; Pyridines; Quinones; Reactive Oxygen Species; Time Factors | 2009 |
Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression.
Topics: Abietanes; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Calreticulin; Carcinoma, Hepatocellular; Caspase 12; Caspase Inhibitors; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cysteine Proteinase Inhibitors; Drugs, Chinese Herbal; Humans; Liver Neoplasms; Male; Mitochondria; Phenanthrenes; Transcription Factor CHOP | 2010 |
Nano-LC-MS/MS based proteomics of hepatocellular carcinoma cells compared to Chang liver cells and tanshinone IIA induction.
Topics: Abietanes; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Movement; Chromatography, Liquid; Cluster Analysis; Humans; Liver; Liver Neoplasms; Mass Spectrometry; Microscopy, Fluorescence; Nanotechnology; Neoplasm Invasiveness; Proteome; Proteomics | 2011 |
Tanshinone IIA activates calcium-dependent apoptosis signaling pathway in human hepatoma cells.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-Associated Death Protein; Calcium Signaling; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mesenchymal Stem Cells; Metallothionein; Microscopy, Fluorescence; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2012 |
Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo.
Topics: Abietanes; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Platelet Endothelial Cell Adhesion Molecule-1; Transplantation, Heterologous | 2012 |
Development of intravenous lipid emulsion of tanshinone IIA and evaluation of its anti-hepatoma activity in vitro.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Stability; Fat Emulsions, Intravenous; Female; Humans; Liver Neoplasms; Male; Mice; Rabbits | 2012 |
Anticancer activities of tanshinone microemulsion against hepatocellular carcinoma in vitro and in vivo.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Emulsions; Female; Gene Expression Regulation, Neoplastic; Liver Neoplasms; Male; Mice; Proto-Oncogene Proteins c-bcl-2; Tumor Burden | 2013 |
Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Growth Processes; Cell Line, Tumor; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Random Allocation; Xenograft Model Antitumor Assays | 2012 |
Novel microemulsion of tanshinone IIA, isolated from Salvia miltiorrhiza Bunge, exerts anticancer activity through inducing apoptosis in hepatoma cells.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Disease Models, Animal; Emulsions; Female; Gene Expression Regulation, Neoplastic; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Salvia miltiorrhiza; Tumor Cells, Cultured | 2013 |
[Effect of tanshinone IIA on the growth behavior of human hepatoma cell line BEL-7402 in vitro and its mechanism].
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Humans; Liver Neoplasms; Microscopy, Electron; Phenanthrenes | 2003 |
Growth inhibition and apoptosis induction in human hepatoma cells by tanshinone II A.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Drugs, Chinese Herbal; Flow Cytometry; Humans; Liver Neoplasms; Phenanthrenes | 2003 |
Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Drugs, Chinese Herbal; Humans; Liver Neoplasms; Phenanthrenes | 2004 |
[Inhibition of cell growth and induction of apoptosis in human hepatoma cell line HepG2 by tanshione IIA].
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flow Cytometry; Humans; Liver Neoplasms; Microscopy, Fluorescence; Phenanthrenes; Time Factors | 2007 |
Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Flow Cytometry; Glutathione; Humans; Liver Neoplasms; Mass Spectrometry; Oxidative Stress; Phenanthrenes; Salvia miltiorrhiza | 2008 |
[An observation of the effect of tanshinone on cancer cell proliferation by Brdu and PCNA labeling].
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; DNA, Neoplasm; Drugs, Chinese Herbal; HL-60 Cells; Humans; Liver Neoplasms; Phenanthrenes; Proliferating Cell Nuclear Antigen; Tumor Cells, Cultured | 1996 |