tanshinone has been researched along with Breast Cancer in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 14 (48.28) | 24.3611 |
| 2020's | 7 (24.14) | 2.80 |
| Authors | Studies |
|---|---|
| Bastow, KF; Don, MJ; Lee, KH; Lin, YL; Nakamura, S; Sun, CM; Wang, X; Wu, TS; Yu, HJ | 1 |
| Banerjee, J; Biswas, N; Bural, S; Dey, A; Gain, C; Kar, GK; Rakshit, M; Saha, A; Sarkar, A | 1 |
| Asili, J; Boozari, M; Emami, SA; Hafezian, T; Hohmann, J; Kúsz, N; Mottaghipisheh, J; Shakeri, A; Tayarani-Najaran, Z | 1 |
| Dai, F; Li, J; Lu, M; Ma, L; Qiu, T; Song, F; Tong, M; Zhang, X | 1 |
| Danish, S; Fengchao, C; Hongquan, W; Jie, L; Kun, L; Qiang, W; Siya, Z; Tongtong, Y | 1 |
| An, C; Cheng, S; Li, S; Liu, G; Pang, B; Sun, S; Wang, J; Zhang, G; Zhang, Y; Zheng, L | 1 |
| Chen, K; Li, LP; Mei, WJ; Qian, J; Wang, T; Wu, Q; Xu, H; Yuan, L; Zeng, L; Zhao, X | 1 |
| Lu, J; Ma, R; Sun, D; Tang, J; Wang, L; Wu, J | 2 |
| Cui, B; Li, S; Lin, H; Lin, Z; Xia, A; Xie, B; Zheng, L; Zhou, P | 1 |
| Fang, T; Lv, C; Nagle, DG; Wang, JX; Wu, T; Yang, PM; Yuan, X; Zeng, HW; Zhang, C; Zhang, WD; Zhou, YD | 1 |
| Huang, X; Li, L; Mei, W; Wu, Q; Zheng, K | 1 |
| Fan, C; Lai, H; Li, K; Li, S; Liu, W; Wu, C; Zhao, Q | 1 |
| Guo, H; Lin, C; Wang, H; Wang, L; Wang, X; Yang, L | 1 |
| Chen, W; Du, F; Fu, P; Liu, Y; Lv, K; Yao, M | 1 |
| Fancellu, G; Nicolin, V; Valentini, R | 1 |
| Chen, Y; Cui, H; Gao, N; Hu, X; Li, G; Liu, L; Shan, C; Zhou, J; Zhou, T | 1 |
| Diel, P; Hegevoss, J; Kulling, SE; Ngueu, S; Soukup, ST; Zhao, P | 1 |
| Chang, KC; Cho, MK; Jeon, SJ; Kang, SS; Kim, HJ; Kim, YS; Lee, GW; Lee, JH; Lee, JS; Nizamutdinova, IT; Seo, HG; Son, KH | 1 |
| Chang, KC; Jeon, SJ; Kang, SS; Kim, HJ; Kim, YS; Lee, GW; Lee, JH; Nizamutdinova, IT; Seo, HG; Son, KH | 1 |
| Lin, YH; Su, CC | 1 |
| Lü, Q; Zhang, PR | 1 |
| Chen, J; Lu, Q; Zhang, P; Zhang, X | 1 |
| Chen, J; Lü, Q; Zhang, PR; Zhang, X | 1 |
| Chen, DR; Chen, YL; Cheng, CY; Chien, SY; Kuo, SJ; Su, CC | 1 |
| Chen, DR; Chien, SY; Kuo, SJ; Su, CC; Yan, MY | 1 |
| Abdolmaleky, HM; Gong, Y; Li, L; Li, Y; Zhou, JR | 1 |
| Liu, G; Lu, Y; Wang, W; Wang, X; Wei, Y; Yuan, S; Zhang, J | 1 |
| Jing, J; Lin, P; Ren, JJ; Wang, J; Wang, XJ; Wu, YY; Xiong, ZJ; Yang, HL; Zhang, J; Zheng, H | 1 |
29 other study(ies) available for tanshinone and Breast Cancer
| Article | Year |
|---|---|
Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Furans; Humans; Pyrones; Receptor, ErbB-2; Receptors, Estrogen; Salvia miltiorrhiza | 2004 |
Identification of two novel thiophene analogues as inducers of autophagy mediated cell death in breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Thiophenes; Unfolded Protein Response | 2021 |
Cytotoxicity, apoptosis inducing activity and Western blot analysis of tanshinone derivatives from Stachys parviflora on prostate and breast cancer cells.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Diterpenes; Humans; Male; Prostate; Stachys | 2022 |
Construction of carboxymethyl chitosan-based nanoparticles of hypoxia response for co-loading doxorubicin and tanshinone IIA.
Topics: Breast Neoplasms; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Carriers; Female; Humans; Nanoparticles | 2023 |
The enhanced cytotoxicity on breast cancer cells by Tanshinone I-induced photodynamic effect.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Photochemotherapy; Photosensitizing Agents | 2023 |
Tanshinone I regulates autophagic signaling via the activation of AMP-activated protein kinase in cancer cells.
Topics: Abietanes; AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Breast Neoplasms; Cell Proliferation; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Signal Transduction; Tumor Cells, Cultured | 2020 |
Selective stabilization of multiple promoter G-quadruplex DNA by using 2-phenyl-1H-imidazole-based tanshinone IIA derivatives and their potential suppressing function in the metastatic breast cancer.
Topics: Abietanes; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; DNA; Drug Screening Assays, Antitumor; G-Quadruplexes; Humans; Imidazoles; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Neoplasm Metastasis; Promoter Regions, Genetic; S Phase Cell Cycle Checkpoints; Structure-Activity Relationship; Zebrafish | 2021 |
[Retracted] Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines.
Topics: Abietanes; Breast Neoplasms; Cell Cycle; Humans; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases | 2021 |
Cytotoxicity of Tanshinone IIA combined with Taxol on drug-resist breast cancer cells MCF-7 through inhibition of Tau.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Paclitaxel | 2018 |
The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Benzoquinones; Biological Products; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; MAP Kinase Signaling System; MCF-7 Cells; Mice, Nude; Phosphatidylinositol 3-Kinases; Protein Kinase C; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Triazoles; Xenograft Model Antitumor Assays | 2018 |
Tanshinone-IIA-Based Analogues of Imidazole Alkaloid Act as Potent Inhibitors To Block Breast Cancer Invasion and Metastasis in Vivo.
Topics: Abietanes; Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Humans; Imidazoles; Models, Molecular; Molecular Conformation; Neoplasm Invasiveness; Neoplasm Metastasis; Xenograft Model Antitumor Assays; Zebrafish | 2018 |
Combination of tanshinone IIA and doxorubicin possesses synergism and attenuation effects on doxorubicin in the treatment of breast cancer.
Topics: Abietanes; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Breast Neoplasms; Down-Regulation; Doxorubicin; Drug Antagonism; Drug Interactions; Drug Synergism; Female; Humans; MCF-7 Cells; Mice; Mice, Nude; PTEN Phosphohydrolase; Xenograft Model Antitumor Assays | 2019 |
Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways.
Topics: Abietanes; Aldehyde Dehydrogenase 1 Family; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Humans; Interleukin-6; Isoenzymes; Neoplastic Stem Cells; NF-kappa B; Retinal Dehydrogenase; Signal Transduction; STAT3 Transcription Factor | 2013 |
Tanshinone IIA blocks epithelial-mesenchymal transition through HIF-1α downregulation, reversing hypoxia-induced chemotherapy resistance in breast cancer cell lines.
Topics: Abietanes; Breast Neoplasms; Cell Hypoxia; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MCF-7 Cells | 2014 |
Effect of tanshinone II on cell growth of breast cancer cell line type MCF-7 and MD-MB-231.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Proliferation; Drugs, Chinese Herbal; Female; Humans; MCF-7 Cells | 2014 |
Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromones; Cyclin-Dependent Kinases; Enzyme Inhibitors; Female; Humans; MCF-7 Cells; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases | 2015 |
Tanshinone IIA inhibits HIF-1α and VEGF expression in breast cancer cells via mTOR/p70S6K/RPS6/4E-BP1 signaling pathway.
Topics: Abietanes; Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Neoplasm Proteins; Neovascularization, Pathologic; Phosphoproteins; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2015 |
Anabolic effect of the traditional Chinese medicine compound tanshinone IIA on myotube hypertrophy is mediated by estrogen receptor.
Topics: Abietanes; Anabolic Agents; Androgen Receptor Antagonists; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Drugs, Chinese Herbal; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; HEK293 Cells; Humans; Hypertrophy; Muscle Fibers, Skeletal; Muscular Atrophy; Phytotherapy; Receptors, Estrogen; Salvia miltiorrhiza; Selective Estrogen Receptor Modulators | 2015 |
Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules.
Topics: Abietanes; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Adhesion; Cell Communication; Cell Proliferation; Endothelial Cells; Female; Humans; Intercellular Adhesion Molecule-1; Mice; Neoplasm Invasiveness; Phenanthrenes; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2008 |
Tanshinone I effectively induces apoptosis in estrogen receptor-positive (MCF-7) and estrogen receptor-negative (MDA-MB-231) breast cancer cells.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Female; Flow Cytometry; Humans; In Situ Nick-End Labeling; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen | 2008 |
Tanshinone IIA inhibits human breast cancer cells through increased Bax to Bcl-xL ratios.
Topics: Abietanes; Actins; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Breast Neoplasms; Caspase 8; Cell Line, Tumor; Humans; Phenanthrenes | 2008 |
[A study on anticancer activity of tanshinone II A against human breast cancer].
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Proliferation; DNA, Neoplasm; Female; Humans; Phenanthrenes; Tumor Cells, Cultured | 2009 |
Experimental study of the anti-cancer mechanism of tanshinone IIA against human breast cancer.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Female; Histocytochemistry; Humans; Mice; Mice, Nude; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Receptor, ErbB-2; Statistics, Nonparametric; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2009 |
[A study on the effect of Tanshinone II A against human breast cancer in vivo].
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Random Allocation; Receptors, Estrogen; Xenograft Model Antitumor Assays | 2010 |
Tanshinone IIA inhibits human breast cancer MDA-MB-231 cells by decreasing LC3-II, Erb-B2 and NF-κBp65.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Humans; Mice; Mice, Nude; Microtubule-Associated Proteins; Receptor, ErbB-2; Transcription Factor RelA; Transplantation, Heterologous | 2012 |
Tanshinone IIA inhibits BT-20 human breast cancer cell proliferation through increasing caspase 12, GADD153 and phospho-p38 protein expression.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caspase 12; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Stress; Female; Gene Expression Regulation, Neoplastic; Humans; p38 Mitogen-Activated Protein Kinases; Transcription Factor CHOP; Up-Regulation | 2012 |
Tanshinones inhibit the growth of breast cancer cells through epigenetic modification of Aurora A expression and function.
Topics: Abietanes; Acetylation; Antineoplastic Agents; Apoptosis; Aurora Kinases; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Epigenesis, Genetic; Female; Gene Expression; Histones; Humans; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Survivin | 2012 |
Potential anticancer activity of tanshinone IIA against human breast cancer.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Transplantation; Phenanthrenes; Transplantation, Heterologous | 2005 |
[Growth inhibition and multidrug resistance-reversing effect of tanshinone I A on human breast cancer cell with estrogen receptor negative].
Topics: Abietanes; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Phenanthrenes; Receptors, Estrogen | 2007 |