tanshinone has been researched along with Atherosclerosis in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (5.88) | 29.6817 |
| 2010's | 20 (58.82) | 24.3611 |
| 2020's | 12 (35.29) | 2.80 |
| Authors | Studies |
|---|---|
| Du, Y; Li, Y; Liu, D; Liu, M; Liu, R; Liu, S; Su, L; Sun, K; Sun, Y; Yu, H; Zhu, X | 1 |
| Gao, Z; Guan, QL; Li, W | 1 |
| Cui, Y; Du, X; Gao, M; Hou, Y; Li, Z; Tian, Z; Wang, J; Xu, J | 1 |
| Gao, F; Jia, W; Li, C; Ma, X; Zhang, L | 1 |
| Lai, H; Li, M; Lin, D; Liu, Y; Ma, L; Niu, C; Pan, Y; Xiao, D; Ye, J; Zhang, L; Zhang, P; Zhuang, R | 1 |
| He, Y; Qian, Y; Qiong, A; Zhang, W | 1 |
| Fan, L; Li, Q; Liu, Q; Wang, X; Yuan, L; Zhang, Z | 1 |
| Chen, W; Guo, J; He, X; Jia, L; Liu, J; Sun, H; Wang, J; Yang, G; Zhang, L; Zhang, N | 1 |
| Chen, W; Guo, S; Li, X; Song, N; Wang, D; Yu, R | 1 |
| Cao, X; Chang, Y; Gao, Y; Huang, H; Huo, S; Li, W; Lin, H; Wen, J; Zhang, J; Zhang, Y; Zhong, F; Zuo, Y | 1 |
| Chen, W; Feng, X; Li, L; Xu, S; Zhang, L; Zhang, S | 1 |
| He, L; Huang, XZ; Li, C; Li, ZZ; Liu, YY; Wang, K; Xiong, Y; Zhang, W | 1 |
| Cai, Y; Gao, Y; Huang, H; Luan, QX; Wang, X; Xuan, Y | 1 |
| Chen, W; Guo, S; Jia, L; Li, X; Song, N; Wang, J; Zhu, A | 1 |
| Chen, LY; Gong, D; Mo, ZC; Ou, HX; Tan, YL; Tang, CK; Xia, XD; Zhang, M; Zhao, ZW | 1 |
| Achenbach, S; Daniel, WG; Fan, Q; Garlichs, CD; Hintermann, C; Kurfürst, I; Losert, S; Pflederer, W; Raaz, D; Stumpf, C | 1 |
| Bi, KW; Chang, CC; Chu, CF; Huang, ST; Pang, JH; Wang, CN; Wu, HT | 1 |
| Gao, S; Huang, E; Li, H; Little, PJ; Liu, P; Liu, Z; Lu, J; Shen, X; Tian, K; Wang, J; Xu, S | 1 |
| Chen, J; Chen, S; Huang, H; Huang, Y; Liu, P; Liu, Z; Shen, X; Xu, S | 1 |
| Guo, CY; Liu, X; Ma, XJ; Pan, YT; Sun, MY; Wu, CF; Yin, HJ; Zhang, Y | 1 |
| Chen, Y; Gong, Z; Guo, Y; Li, Q; Li, Y; Liu, X; Wang, Y; Weng, X; Yang, Q; You, Y; Zhang, R; Zhou, B; Zhu, X | 1 |
| Li, H; Tong, L; Wan, Y; Zhang, L; Zhang, T; Zhao, D | 1 |
| Fang, J; Little, PJ; Xu, S | 1 |
| Cao, Y; Guo, J; Huang, HQ; Liu, PQ; Liu, WH; Tang, FT; Wang, LJ; Wang, TQ; Xu, SW; Zhou, XS | 1 |
| Chen, WN; Chen, Y; Feng, JY; Jia, LQ; Yang, GL | 1 |
| Cai, Y; Huang, H; Huang, Y; Lan, T; Le, K; Little, PJ; Liu, P; Shen, X; Tang, F; Wang, H; Wu, X; Xu, S | 1 |
| Chen, S; Chen, W; Huang, H; Liu, P; Tang, F; Xie, B | 1 |
| Huang, H; Huang, Y; Le, K; Little, PJ; Liu, P; Liu, Z; Ogura, S; Shen, X; Tang, F; Xu, S | 1 |
| Cao, Y; Chen, WN; Feng, JY; Jia, LQ; Lei, P; Li, XT; Ren, L; Yang, GL; Zhang, L | 1 |
| Chen, Q; Fu, Q; Huang, GS; Li, HZ; Li, ZL; Lu, YH | 1 |
| He, H; Liu, J; Wang, J; Wu, Z; Zhang, S; Zhang, W | 1 |
| Tian, XH; Wu, JH | 1 |
| Bao, L; Chen, S; Gao, J; Huang, H; Li, R; Liu, P; Tang, F; Wang, P; Wang, T; Wu, X; Zhang, H | 1 |
| Fang, ZY; Lin, R; Liu, Y; Yang, GD; Yuan, BX; Zhang, H | 1 |
3 review(s) available for tanshinone and Atherosclerosis
| Article | Year |
|---|---|
Natural products: The role and mechanism in low-density lipoprotein oxidation and atherosclerosis.
Topics: Abietanes; Antioxidants; Atherosclerosis; Biological Products; Catechin; Dietary Supplements; Humans; Lipoproteins, LDL; Lycopene; Phytotherapy; Plant Extracts; Probucol; Quercetin; Resveratrol; Vitamin E | 2021 |
Atheroprotective Effects and Molecular Targets of Tanshinones Derived From Herbal Medicine Danshen.
Topics: Abietanes; Animals; Atherosclerosis; Drugs, Chinese Herbal; Humans; Molecular Targeted Therapy; Salvia miltiorrhiza | 2018 |
Tanshinone derivatives: a patent review (January 2006 - September 2012).
Topics: Abietanes; Animals; Atherosclerosis; Cardiovascular Diseases; Drug Design; Drugs, Chinese Herbal; Humans; Neoplasms; Neurodegenerative Diseases; Patents as Topic; Prodrugs; Solubility | 2013 |
31 other study(ies) available for tanshinone and Atherosclerosis
| Article | Year |
|---|---|
Tanshinone IIA-Loaded Micelles Functionalized with Rosmarinic Acid: A Novel Synergistic Anti-Inflammatory Strategy for Treatment of Atherosclerosis.
Topics: Abietanes; Amides; Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cinnamates; Depsides; Endothelial Cells; Lipopolysaccharides; Mice; Micelles; NF-kappa B; Polyethylene Glycols; Polymers; Reactive Oxygen Species; Rosmarinic Acid; Vascular Cell Adhesion Molecule-1 | 2022 |
Tan IIA mitigates vascular smooth muscle cell proliferation and migration induced by ox-LDL through the miR-137/TRPC3 axis.
Topics: Apoptosis; Atherosclerosis; Cell Movement; Cell Proliferation; Cells, Cultured; Humans; Lipoproteins, LDL; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proliferating Cell Nuclear Antigen; RNA, Long Noncoding | 2023 |
Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis.
Topics: Animals; Atherosclerosis; Hypoxia; Interleukin-1beta; Mice; Molecular Docking Simulation; Plaque, Atherosclerotic; Succinates; Succinic Acid | 2023 |
Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cyclooxygenase 2; Inflammation; Mice; Molecular Docking Simulation; NF-kappa B; Plaque, Atherosclerotic; Salvia miltiorrhiza | 2023 |
Molecular targets and mechanisms of Guanxinning tablet in treating atherosclerosis: Network pharmacology and molecular docking analysis.
Topics: Atherosclerosis; Drugs, Chinese Herbal; ErbB Receptors; Humans; Mitogen-Activated Protein Kinase 14; Molecular Docking Simulation; Network Pharmacology; Phosphatidylinositol 3-Kinases | 2023 |
Tanshinone IIA Regulates MAPK/mTOR Signal-Mediated Autophagy to Alleviate Atherosclerosis through the miR-214-3p/ATG16L1 Axis.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Cholesterol; Lipoproteins, LDL; Mice; MicroRNAs; Mitogen-Activated Protein Kinases; TOR Serine-Threonine Kinases | 2023 |
Tanshinone IIA inhibits the adipogenesis and inflammatory response in ox-LDL-challenged human monocyte-derived macrophages via regulating miR-130b/WNT5A.
Topics: Abietanes; Adipogenesis; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Atherosclerosis; Gene Expression Regulation; Humans; Inflammation; Lipoproteins, LDL; Macrophages; MicroRNAs; Wnt-5a Protein | 2020 |
Tanshinone IIA protects mice against atherosclerotic injury by activating the TGF-β/PI3K/Akt/eNOS pathway.
Topics: Abietanes; Animals; Aorta, Thoracic; Atherosclerosis; Biomarkers; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Transforming Growth Factor beta | 2020 |
The regulated profile of noncoding RNAs associated with inflammation by tanshinone IIA on atherosclerosis.
Topics: Abietanes; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Disease Models, Animal; Gene Expression Regulation; Gene Ontology; Genes, Reporter; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs; RAW 264.7 Cells; Reproducibility of Results; RNA, Circular; RNA, Long Noncoding; Triglycerides | 2020 |
Tanshinone IIA attenuates atherosclerosis via inhibiting NLRP3 inflammasome activation.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Atherosclerosis; CD36 Antigens; Diet, High-Fat; Inflammasomes; Lipoproteins, LDL; Macrophages; Mice; Mice, Knockout, ApoE; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Scavenger Receptors, Class E | 2020 |
Tanshinone IIA protects human coronary artery endothelial cells from ferroptosis by activating the NRF2 pathway.
Topics: Abietanes; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Cells, Cultured; Coronary Vessels; Endothelial Cells; Ferroptosis; Humans; Lipid Peroxidation; NF-E2-Related Factor 2; Signal Transduction | 2021 |
Tanshinone IIA Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice Infected with Porphyromonas gingivalis.
Topics: Abietanes; Animals; Apolipoproteins E; Atherosclerosis; Bacteroidaceae Infections; Cytokines; Down-Regulation; Mice; Mice, Knockout; MicroRNAs; Porphyromonas gingivalis | 2017 |
Tanshinone IIA harmonizes the crosstalk of autophagy and polarization in macrophages via miR-375/KLF4 pathway to attenuate atherosclerosis.
Topics: Abietanes; Animals; Apolipoproteins E; Atherosclerosis; Autophagy; Cell Differentiation; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Receptor Cross-Talk; Salvia miltiorrhiza; Signal Transduction | 2019 |
Tanshinone IIA Promotes Macrophage Cholesterol Efflux and Attenuates Atherosclerosis of apoE-/- Mice by Omentin-1/ABCA1 Pathway.
Topics: Abietanes; Animals; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; Biological Transport; Cell Line, Tumor; Cholesterol; Cytokines; GPI-Linked Proteins; Humans; Lectins; Lipid Metabolism; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; Up-Regulation | 2019 |
Anti-inflammatory effects of danshen on human vascular endothelial cells in culture.
Topics: Abietanes; Adenosine Diphosphate; Anti-Inflammatory Agents; Atherosclerosis; Benzofurans; Blood Platelets; CD40 Antigens; Cells, Cultured; Chemokine CCL2; Down-Regulation; Drugs, Chinese Herbal; Human Umbilical Vein Endothelial Cells; Humans; Hydroxybenzoates; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; P-Selectin; Salvia miltiorrhiza; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2013 |
The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF-α-induced VCAM-1, ICAM-1 and CX3CL1 expression.
Topics: Abietanes; Anti-Inflammatory Agents; Atherosclerosis; Chemokine CX3CL1; Drugs, Chinese Herbal; E-Selectin; Human Umbilical Vein Endothelial Cells; Humans; I-kappa B Proteins; Intercellular Adhesion Molecule-1; NF-kappa B; NF-KappaB Inhibitor alpha; Phytotherapy; RNA, Messenger; Salvia miltiorrhiza; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2014 |
Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1.
Topics: Abietanes; Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cholesterol; DNA; Enzyme Activation; Heme Oxygenase-1; Humans; Lipoproteins, LDL; Macrophages; Mice; Receptors, Scavenger; Transcription Factor AP-1; Transcription, Genetic; Up-Regulation | 2014 |
Effectiveness of combination therapy of atorvastatin and non lipid-modifying tanshinone IIA from Danshen in a mouse model of atherosclerosis.
Topics: Abietanes; Animals; Atherosclerosis; Atorvastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drugs, Chinese Herbal; Heptanoic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrroles; Salvia miltiorrhiza; Treatment Outcome | 2014 |
Anti-inflammatory effects of tanshinone IIA on atherosclerostic vessels of ovariectomized ApoE mice are mediated by estrogen receptor activation and through the ERK signaling pathway.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins E; Atherosclerosis; Diet, High-Fat; Disease Models, Animal; Estradiol; Estrogens; Extracellular Signal-Regulated MAP Kinases; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Ovariectomy; Oxidative Stress; Receptors, Estrogen; Signal Transduction; Superoxide Dismutase; Triglycerides | 2015 |
Establishment of an interleukin-1β-induced inflammation-activated endothelial cell-smooth muscle cell-mononuclear cell co-culture model and evaluation of the anti-inflammatory effects of tanshinone IIA on atherosclerosis.
Topics: Abietanes; Anti-Inflammatory Agents; Atherosclerosis; Atorvastatin; Cell Proliferation; Cells, Cultured; Coculture Techniques; Connexins; Cytokines; Diterpenes; Endothelial Cells; Humans; Inflammation Mediators; Interleukin-1beta; Lipoproteins, LDL; Models, Biological; Myocytes, Smooth Muscle; NF-kappa B; Nitric Oxide; PPAR gamma | 2015 |
Tanshinone II A stabilizes vulnerable plaques by suppressing RAGE signaling and NF-κB activation in apolipoprotein-E-deficient mice.
Topics: Abietanes; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Biopsy; Disease Models, Animal; Immunohistochemistry; Inflammation Mediators; Male; MAP Kinase Signaling System; Matrix Metalloproteinases; Mice; Mice, Knockout; NF-kappa B; Plaque, Atherosclerotic; Receptor for Advanced Glycation End Products; Signal Transduction | 2016 |
Tanshinone IIA attenuates atherosclerosis in ApoE(-/-) mice through down-regulation of scavenger receptor expression.
Topics: Abietanes; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta, Thoracic; Aortic Valve; Apolipoproteins E; Atherosclerosis; Biological Transport; Body Weight; CD36 Antigens; Cell Survival; Cholesterol; Down-Regulation; Humans; Lipid Metabolism; Lipoproteins, LDL; Liver; Macrophages; Male; Malondialdehyde; Mice; Phenanthrenes; PPAR gamma; RNA, Messenger; Scavenger Receptors, Class A | 2011 |
[Effect of tanshinone II A on TLR4 and TNF-α of endothelial cells induced by LPS].
Topics: Abietanes; Atherosclerosis; Cell Line; Endothelial Cells; Gene Expression Regulation; Humans; Lipopolysaccharides; RNA, Messenger; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2011 |
Tanshinone II-A attenuates and stabilizes atherosclerotic plaques in apolipoprotein-E knockout mice fed a high cholesterol diet.
Topics: Abietanes; Animals; Apolipoproteins E; Atherosclerosis; Cholesterol, Dietary; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout | 2011 |
Amelioration of atherosclerosis by tanshinone IIA in hyperlipidemic rabbits through attenuation of oxidative stress.
Topics: Abietanes; Animals; Antioxidants; Aorta, Thoracic; Atherosclerosis; Cholesterol; Disease Progression; Glutathione Peroxidase; Hyperlipidemias; Lipoproteins, LDL; Male; Malondialdehyde; Oxidative Stress; Rabbits; Superoxide Dismutase | 2012 |
Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-κB activation.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apolipoproteins E; Atherosclerosis; Cell Line; Drugs, Chinese Herbal; Foam Cells; Gene Expression; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Mice, Mutant Strains; NF-kappa B; Reactive Oxygen Species; Scavenger Receptors, Class E; Superoxides; Translational Research, Biomedical | 2012 |
Tanshinone IIA reduces apoptosis induced by hydrogen peroxide in the human endothelium-derived EA.hy926 cells.
Topics: Abietanes; Antioxidants; Apoptosis; Atherosclerosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Survival; Drugs, Chinese Herbal; Endothelial Cells; Humans; Hydrogen Peroxide; Oxidative Stress; Phenanthrolines; Phytotherapy; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Salvia miltiorrhiza | 2012 |
Tanshinone II A inhibits dendritic cell-mediated adaptive immunity: potential role in anti-atherosclerotic activity.
Topics: Abietanes; Antigen-Presenting Cells; Atherosclerosis; B7-2 Antigen; Cell Membrane; Cytokines; Dendritic Cells; Endocytosis; Flow Cytometry; Humans; Immunity, Cellular; Inflammation Mediators; Lymphocyte Activation | 2014 |
Pharmacokinetics and atherosclerotic lesions targeting effects of tanshinone IIA discoidal and spherical biomimetic high density lipoproteins.
Topics: Abietanes; Animals; Aorta, Thoracic; Atherosclerosis; Azo Compounds; Biomimetic Materials; Carotid Intima-Media Thickness; Cholesterol; Collagen; Disease Models, Animal; Lipoproteins; Lipoproteins, HDL; Macrophages; Phosphatidylcholine-Sterol O-Acyltransferase; Rabbits; Recombinant Proteins; Static Electricity; Transcription Factor RelA | 2013 |
Tanshinone II A attenuates atherosclerotic calcification in rat model by inhibition of oxidative stress.
Topics: Abietanes; Animals; Antioxidants; Aorta, Thoracic; Atherosclerosis; Calcinosis; Calcium; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Induction; Ergocalciferols; Lipoproteins, LDL; Male; Malondialdehyde; Oxidative Stress; Phenanthrenes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase; Superoxides; Time Factors | 2007 |
Tanshinone IIA downregulates the CD40 expression and decreases MMP-2 activity on atherosclerosis induced by high fatty diet in rabbit.
Topics: Abietanes; Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; CD40 Antigens; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Female; Male; Malondialdehyde; Matrix Metalloproteinase 2; Phenanthrenes; Plant Roots; Rabbits; Salvia miltiorrhiza; Superoxide Dismutase | 2008 |