tanshinone has been researched along with Alzheimer Disease in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 11 (57.89) | 24.3611 |
| 2020's | 7 (36.84) | 2.80 |
| Authors | Studies |
|---|---|
| Ba, Z; He, Y; Huang, J; Huang, N; Li, Y; Liu, D; Luo, Y; Shi, S; Yang, X; You, C; Yu, C | 1 |
| Chen, L; Guo, H; He, Y; Ji, S; Peng, X; Ruganzu, JB; Wang, Z; Yang, W; Zhang, X; Zheng, L | 1 |
| Chang, Y; Du, L; Huang, Y; Kang, X; Liu, Y; Wang, J; Wang, S; Zhang, L; Zhang, X; Zhao, Y | 1 |
| Al Abdulmonem, W; Alhumaydhi, FA; Alrouji, M; Anwar, S; Atiya, A; Majrashi, TA; Shahwan, M; Shamsi, A; Sharaf, SE; Zari, A; Zari, TA | 1 |
| Bi, D; Cai, N; Chen, J; Gu, L; Hu, Z; Li, H; Li, X; Liu, Q; Xu, H; Xu, X; Yao, L | 1 |
| Bednarikova, Z; Gancar, M; Gazova, Z; Huang, Y; Luo, Y; Ma, L; Spodniakova, B; Tang, Y; Wang, R; Zheng, L | 1 |
| Gaire, BP; Subedi, L | 1 |
| Ba, Z; Feng, F; Huang, N; Li, Y; Luo, Y; Shi, S; Zhou, Y | 1 |
| Dai, X; Liang, S; Qin, F; Sun, Y; Wang, Z; Yuan, J; Zhang, J | 1 |
| Buenafe, OE; Crawford, AD; De Borggraeve, W; de Witte, P; Esguerra, CV; Huang, H; Luyten, W; Maes, J; Orellana-Paucar, A; Ying, X | 1 |
| Li, W; Luo, H; Song, Z; Wen, P; Zhou, J; Zhou, L | 1 |
| Jiang, P; Jiao, B; Li, C; Xiang, Z | 1 |
| Li, J; Li, WW; Wen, PY; Zhou, J | 1 |
| Li, J; Li, W; Wang, F; Zhou, J | 1 |
| Fei, Y; Hu, X; Liu, C; Liu, M; Ma, K; Qian, Y; Wang, Y; Wu, Y; Yang, G; Yang, W; Zha, S; Zhang, Y | 1 |
| Li, J; Li, WW; Lu, BL; Wu, HF; Zhou, J | 1 |
| Cerón-Carrasco, JP; den-Haan, H; Domaradzki, K; Girón-Rodríguez, F; Matkowski, A; Orhan, IE; Peña-García, J; Pérez-Garrido, A; Pérez-Sánchez, H; Senol, FS; Ślusarczyk, S | 1 |
| Li, H; Liu, JG; Wang, ZY; Yang, HM | 1 |
| Chen, X; Huang, L; Huang, S; Liu, Y; Shao, F; Wu, H; Yin, Y; Zhang, L; Zhao, Z; Zhuang, J | 1 |
2 review(s) available for tanshinone and Alzheimer Disease
| Article | Year |
|---|---|
Tanshinone IIA: A phytochemical as a promising drug candidate for neurodegenerative diseases.
Topics: Abietanes; Alzheimer Disease; Animals; Brain Ischemia; Humans; Multiple Sclerosis; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease | 2021 |
Pharmacological Effects of Active Components of Chinese Herbal Medicine in the Treatment of Alzheimer's Disease: A Review.
Topics: Abietanes; Alkaloids; Alzheimer Disease; Curcuma; Curcumin; Drugs, Chinese Herbal; Epimedium; Evodia; Flavonoids; Ginsenosides; Humans; Huperzia; Panax; Phytotherapy; Plant Extracts; Quinazolines; Salvia miltiorrhiza; Scutellaria baicalensis; Sesquiterpenes | 2016 |
17 other study(ies) available for tanshinone and Alzheimer Disease
| Article | Year |
|---|---|
Mesenchymal stem cells after the proprocessing of tanshinone IIA attenuate cognitive deficits and oxidative stress injury in an amyloid β-peptide (25-35)-induced rodent model of Alzheimer's disease.
Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Disease Models, Animal; Hippocampus; Male; Mesenchymal Stem Cells; Oxidative Stress; Peptide Fragments; Rats; Rats, Sprague-Dawley; Rodentia | 2022 |
Tanshinone IIA regulates glycogen synthase kinase-3β-related signaling pathway and ameliorates memory impairment in APP/PS1 transgenic mice.
Topics: Abietanes; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Cognition; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Memory Disorders; Mice; Mice, Transgenic; Nootropic Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Salvia miltiorrhiza; Signal Transduction | 2022 |
Tanshinone IIA loaded chitosan nanoparticles decrease toxicity of β-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease.
Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Caenorhabditis elegans; Chitosan; Humans; Nanoparticles; Superoxide Dismutase | 2022 |
Unveiling Phytoconstituents with Inhibitory Potential Against Tyrosine-Protein Kinase Fyn: A Comprehensive Virtual Screening Approach Targeting Alzheimer's Disease.
Topics: Alzheimer Disease; Humans; Molecular Docking Simulation; Neoplasms; Phytochemicals; Proto-Oncogene Proteins c-fyn; Tyrosine | 2023 |
Specific Degradation of Endogenous Tau Protein and Inhibition of Tau Fibrillation by Tanshinone IIA through the Ubiquitin-Proteasome Pathway.
Topics: Abietanes; Alzheimer Disease; Animals; Cell Line; Drugs, Chinese Herbal; Humans; Mice; Mice, Transgenic; Neurons; Proteasome Endopeptidase Complex; Proteolysis; Salvia miltiorrhiza; tau Proteins; Ubiquitins | 2020 |
Extracts from Chinese herbs with anti-amyloid and neuroprotective activities.
Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Anemarrhena; Benzofurans; Cell Line; China; Humans; Neuroprotective Agents; Peptide Fragments; Plant Extracts; Salvia miltiorrhiza; Spirostans | 2021 |
Neuroprotective effect of tanshinone IIA-incubated mesenchymal stem cells on Aβ
Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Hippocampus; Learning; Male; Memory; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neuroimmunomodulation; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2019 |
Rapid Identification of Tanshinone IIA Metabolites in an Amyloid-β
Topics: Abietanes; Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; Chromatography, High Pressure Liquid; Disease Models, Animal; Male; Mass Spectrometry; Metabolomics; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2019 |
Tanshinone IIA exhibits anticonvulsant activity in zebrafish and mouse seizure models.
Topics: Abietanes; Alzheimer Disease; Animals; Anticonvulsants; Brain Ischemia; Disease Models, Animal; Disease Progression; Drugs, Chinese Herbal; Fertilization in Vitro; Injections, Intraventricular; Larva; Male; Medicine, Chinese Traditional; Mice; Microinjections; Neuroprotective Agents; Pentylenetetrazole; Plant Extracts; Plant Roots; Proto-Oncogene Proteins c-fos; Salvia miltiorrhiza; Seizures; Small Molecule Libraries; Zebrafish | 2013 |
[Effects of tanshinone IIA on the expressions of caspase-3, Akt and NF-κB in the brains of rat models of Alzheimer's disease].
Topics: Abietanes; Alzheimer Disease; Animals; Apoptosis; Brain; Caspase 3; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Male; Neuroprotective Agents; NF-kappa B; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley | 2014 |
Tanshinone IIA reduces the risk of Alzheimer's disease by inhibiting iNOS, MMP‑2 and NF‑κBp65 transcription and translation in the temporal lobes of rat models of Alzheimer's disease.
Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Male; Matrix Metalloproteinase 2; Maze Learning; Memory; Neuroprotective Agents; Nitric Oxide Synthase Type II; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Temporal Lobe; Transcription Factor RelA | 2014 |
Upregulation effects of Tanshinone IIA on the expressions of NeuN, Nissl body, and IκB and downregulation effects on the expressions of GFAP and NF-κB in the brain tissues of rat models of Alzheimer's disease.
Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Nuclear; Brain; Disease Models, Animal; Down-Regulation; Glial Fibrillary Acidic Protein; I-kappa B Proteins; Male; Nerve Tissue Proteins; Neuroprotective Agents; NF-kappa B; Nissl Bodies; Peptide Fragments; Rats; Rats, Sprague-Dawley; Up-Regulation | 2015 |
[Effects of tanshinone IIA on the expressions of p53, pp53 and apoptosis in the rats with Alzheimer's disease].
Topics: Abietanes; Alzheimer Disease; Animals; Apoptosis; Brain; Down-Regulation; Male; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 2015 |
Treatment effects of tanshinone IIA against intracerebroventricular streptozotocin induced memory deficits in mice.
Topics: Abietanes; Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Infusions, Intraventricular; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Parietal Lobe; Random Allocation; Streptozocin; Superoxide Dismutase | 2016 |
Tanshinone IIA decreases the levels of inflammation induced by Aβ1-42 in brain tissues of Alzheimer's disease model rats.
Topics: Abietanes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Astrocytes; Brain; CD11b Antigen; Complement C1q; Complement C3c; Complement C3d; Disease Models, Animal; Encephalitis; Interleukin-1beta; Interleukin-6; Male; Peptide Fragments; Rats, Sprague-Dawley | 2016 |
Selective in vitro and in silico butyrylcholinesterase inhibitory activity of diterpenes and rosmarinic acid isolated from Perovskia atriplicifolia Benth. and Salvia glutinosa L.
Topics: Abietanes; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Cinnamates; Depsides; Diterpenes; Drugs, Chinese Herbal; Lamiaceae; Phenanthrenes; Quantitative Structure-Activity Relationship; Rosmarinic Acid; Salvia | 2017 |
Effect of tanshinone on the levels of nitric oxide synthase and acetylcholinesterase in the brain of Alzheimer's disease rat model.
Topics: Abietanes; Acetylcholinesterase; Alzheimer Disease; Animals; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hippocampus; Immunosuppressive Agents; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Phenanthrenes; Rats; Rats, Sprague-Dawley | 2008 |