tannins and Uremia

tannins has been researched along with Uremia* in 2 studies

Trials

1 trial(s) available for tannins and Uremia

Article	Year
[Lespedeza (Lespedeza Rich.): its distribution, chemical composition and use]. Farmatsevtychnyi zhurnal, 1979, Issue:2 Topics: Animals; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Diuretics; Drug Evaluation, Preclinical; Flavonoids; Humans; Kidney Diseases; Phenols; Plants, Medicinal; Tannins; Uremia; USSR	1979

Other Studies

1 other study(ies) available for tannins and Uremia

Article	Year
Effects of rhubarb tannins on uremic toxins. Nephron, 1991, Volume: 58, Issue:2 The effects of each of several tannins purified from Rhei Rhizoma on serum constituents were investigated in rats with adenine-induced renal failure. Blood levels of urea nitrogen, methylguanidine (MG), and guanidinosuccinic acid (GSA) were significantly decreased in rats given (-)-epicatechin 3-O-gallate at a dose of 2.5, 5 or 10 mg/kg body weight/day for 24 days. The creatinine (Cr) level was also significantly decreased in rats given 5 and 10 mg of this compound. A significant decrease in urea nitrogen, MG, and GSA was found in rats given 6.25 mg of procyanidin B-2 3,3'-di-O-gallate. However, unlike the former two components the administration of 12.5 mg of procyanidin C-1 3,3',3''-tri-O-gallate produced a considerable or significant increase in bLood levels of urea nitrogen, Cr, MG, and GSA. RG-tannin had a weaker overall effect on serum constituents except for GSA in comparison with the corresponding effect of (-)-epicatechin 3-O-gallate and 6.25 mg of procyanidin B-2 3,3'-di-O-gallate. Rhatannin tended to increase the serum nitrogen constituents. Topics: Animals; Biflavonoids; Blood Urea Nitrogen; Catechin; Creatinine; Drugs, Chinese Herbal; Guanidines; Male; Methylguanidine; Plants, Medicinal; Proanthocyanidins; Rats; Rats, Inbred Strains; Rheum; Structure-Activity Relationship; Succinates; Tannins; Toxins, Biological; Uremia	1991

Article

Year

Effects of rhubarb tannins on uremic toxins.

Nephron, 1991, Volume: 58, Issue:2

The effects of each of several tannins purified from Rhei Rhizoma on serum constituents were investigated in rats with adenine-induced renal failure. Blood levels of urea nitrogen, methylguanidine (MG), and guanidinosuccinic acid (GSA) were significantly decreased in rats given (-)-epicatechin 3-O-gallate at a dose of 2.5, 5 or 10 mg/kg body weight/day for 24 days. The creatinine (Cr) level was also significantly decreased in rats given 5 and 10 mg of this compound. A significant decrease in urea nitrogen, MG, and GSA was found in rats given 6.25 mg of procyanidin B-2 3,3'-di-O-gallate. However, unlike the former two components the administration of 12.5 mg of procyanidin C-1 3,3',3''-tri-O-gallate produced a considerable or significant increase in bLood levels of urea nitrogen, Cr, MG, and GSA. RG-tannin had a weaker overall effect on serum constituents except for GSA in comparison with the corresponding effect of (-)-epicatechin 3-O-gallate and 6.25 mg of procyanidin B-2 3,3'-di-O-gallate. Rhatannin tended to increase the serum nitrogen constituents.

Topics: Animals; Biflavonoids; Blood Urea Nitrogen; Catechin; Creatinine; Drugs, Chinese Herbal; Guanidines; Male; Methylguanidine; Plants, Medicinal; Proanthocyanidins; Rats; Rats, Inbred Strains; Rheum; Structure-Activity Relationship; Succinates; Tannins; Toxins, Biological; Uremia

1991