tannins and Skin-Diseases

This clinical study was performed to evaluate the effects of continuous apple polyphenol (AP) administration on facial skin conditions and pigmentation induced by ultraviolet (UV) irradiation in healthy women participants. Participants (n = 65, age 20-39 years) were randomized to receive tablets containing AP (300 or 600 mg/day) or placebo in a double-blinded, placebo-controlled clinical trial. Continuous administration of AP for 12 weeks significantly prevented UV irradiation induced skin pigmentation (erythema value, melanin value, L value), although a dose-dependent relationship was not clearly observed. In contrast, no significant differences were detected between the groups with regard to water content and trans-epidermal water loss. Our study demonstrated that APs and their major active compounds, procyanidins, have several health benefits. Here, we report that continuous administration of AP for 12 weeks alleviated UV irradiation induced skin pigmentation, when compared with placebo, in healthy women.

Topics: Adult; Body Water; Chlorogenic Acid; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flavonoids; Humans; Male; Proanthocyanidins; Skin; Skin Diseases; Skin Pigmentation; Tannins; Time Factors; Ultraviolet Rays; Water Loss, Insensible; Young Adult

In this study, we investigated how tannic acid (TA) protects the skin from inflammation caused by external irritation. The effects of TA were evaluated using a mouse 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced skin inflammation model and a reconstructed human epidermal model. We then used Lucifer Yellow for visual confirmation of TA's suppression effect at the stratum corneum (SC) surface. TA treatment of the skin prevented Lucifer Yellow from permeating the skin. This result suggests that TA acts as a barrier against external stimulants such as TPA and artificial sweat on the SC surface.

Topics: Animals; Dermatitis, Contact; Disease Models, Animal; Epidermis; Fluorescent Dyes; Inflammation; Isoquinolines; Male; Mice; Mice, Inbred ICR; Permeability; Skin; Skin Diseases; Sweat; Tannins; Tetradecanoylphorbol Acetate

Topics: Burns; Dermatitis; Dermatomycoses; History, 20th Century; Humans; Intertrigo; Skin Diseases; Sunburn; Sweating; Tannins

Topics: Adolescent; Age Factors; Agglutination Tests; Animals; Antibodies; Child; Child, Preschool; Epilepsy; Female; gamma-Globulins; Gastrointestinal Diseases; Humans; Immunodiffusion; Immunoelectrophoresis; Infant; Infant, Newborn; Iodine Isotopes; Male; Milk; Respiratory Tract Diseases; Serum Albumin, Bovine; Skin Diseases; Tannins

Topics: Acetates; Acute Disease; Agar; Animals; Bile; Calcium Chloride; Carrageenan; Chlorides; Copper; Croton Oil; Ethanol; Female; Formaldehyde; Glucose; Histamine; Indium; Lead; Manganese; Mercury; Necrosis; Papain; Phosphates; Polymyxins; Polysaccharides; Rats; Skin Diseases; Tannins; Trypsin; Zinc

Topics: Animals; Hemorrhagic Disorders; Norepinephrine; Rats; Shwartzman Phenomenon; Skin Diseases; Tannins; Thorium Dioxide; Thrombosis

Topics: Gastrointestinal Diseases; Humans; Male; Middle Aged; Ointments; Pancreatic Fistula; Postoperative Complications; Skin Diseases; Tannins; Zinc

Topics: Biomedical Research; Humans; Nitrofurazone; Skin Diseases; Tannins

Topics: Benzopyrans; Humans; Light; Skin Diseases; Tannins

Topics: Humans; Skin Diseases; Tannins

Topics: Benzopyrans; Humans; Skin Diseases; Tannins

Topics: Skin Diseases; Tannins; X-Ray Therapy; X-Rays