tannins has been researched along with Sarcoma-180* in 4 studies
4 other study(ies) available for tannins and Sarcoma-180
Article | Year |
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Host-mediated anticancer activities of tannins.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Benzopyrans; Caffeic Acids; Cell Survival; Drug Screening Assays, Antitumor; Female; Flavonoids; Hydrolyzable Tannins; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phenols; Polymers; Polyphenols; Sarcoma 180; Spleen; Structure-Activity Relationship; Tannins; Tumor Cells, Cultured | 1999 |
Antitumor activities of ellagitannins against sarcoma-180 in mice.
Forty-five ellagitannins and related compounds were intraperitoneally injected into mice once, 4 d before intraperitoneal inoculation of S-180 cells, and their antitumor activities were evaluated. When an antitumor-active tannin was defined as one producing a 70% increase or more in the mean life span of mice or one regressor out of six mice, twenty-one ellagitannins were active. Among monomeric ellagitannins, tellimagrandin II was most active. Most of the oligomeric ellagitannins, consisting of tellimagrandins I and II as the monomer unit, had a significant antitumor activity. Macrocyclic ellagitannins were all active. Oenothein B, among them, had the most potent antitumor activity. In contrast, ellagitannins containing a casuarictin or potentillin moiety in their molecules, except for extensively oligomerized ones, showed very low or negligible activity. These results suggest that tannins need the ellagitannin monomer units, having galloyl groups at the O-2 and O-3 positions on the glucose core(s), such as tellimagrandins, in order to exhibit a strong antitumor activity. Topics: Animals; Antineoplastic Agents, Phytogenic; Female; Hydrolyzable Tannins; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Sarcoma 180; Structure-Activity Relationship; Tannins | 1993 |
Camelliin B and nobotanin I, macrocyclic ellagitannin dimers and related dimers, and their antitumor activity.
Camelliin B and nobotanin I, dimeric hydrolyzable tannins of a new class having macrocyclic structures, were isolated from Camellia japonica and Heterocentron roseum, respectively. Nobotanin G and H of the structures related to nobotanin I, were also obtained from H. roseum. Camelliin B and also woodfordin C, a macrocyclic dimer from Woodfordia fruticosa, exhibited marked host-mediated antitumor activities. Topics: Animals; Antineoplastic Agents, Phytogenic; Chemical Phenomena; Chemistry; Hydrolyzable Tannins; Injections, Intraperitoneal; Mice; Sarcoma 180; Tannins | 1989 |
Relationship between the structures and the antitumor activities of tannins.
Topics: Animals; Antineoplastic Agents; Female; Mice; Mice, Inbred Strains; Sarcoma 180; Structure-Activity Relationship; Tannins | 1987 |