tannins and Autoimmune-Diseases

Topics: Animals; Antigens; Autoantibodies; Autoimmune Diseases; Epitopes; Female; Freund's Adjuvant; Germ-Free Life; Hemagglutination Tests; Pertussis Vaccine; Rats; Rats, Inbred Strains; Species Specificity; Tannins; Thyroid Gland; Thyroiditis

Several antibodies have been reported in selective IgA deficiency and we have detected antibodies to human IgM and native human collagen in 35 and 34%, respectively, of 60 such subjects (compared to 1.6 and 2.0%, respectively, in normal controls). The anti-IgM isoantibodies are clearly distinguishable from antibodies to ruminant proteins and there was no statistically significant association between different antibodies and clinical features in individual patients. The etiology of the antibodies remains unknown.

Topics: Adolescent; Adult; Antibody Formation; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Child; Child, Preschool; Collagen; Epitopes; Erythrocytes; Female; Hemagglutination Tests; Humans; IgA Deficiency; Immunodiffusion; Immunoglobulin M; Isoantibodies; Macroglobulins; Male; Tannins

Topics: Animals; Antibodies; Antigens; Autoimmune Diseases; Blood Cell Count; Bone Marrow Examination; Cytarabine; Guinea Pigs; Hemagglutination Tests; Immunization; Liver; Lymph Nodes; Male; Skin Tests; Spleen; Tannins; Thymus Gland; Thyroid Gland; Thyroiditis; Tissue Extracts