tamibarotene has been researched along with Acute Promyelocytic Leukemia in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.57) | 18.7374 |
| 1990's | 6 (17.14) | 18.2507 |
| 2000's | 9 (25.71) | 29.6817 |
| 2010's | 16 (45.71) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Himi, T; Kagechika, H; Kawachi, E; Shudo, K | 1 |
| Hashimoto, Y; Himi, T; Kagechika, H; Kawachi, E; Shudo, K | 1 |
| Baker, K; Banos, A; Bixby, D; Braun, T; Carulli, J; Cluzeau, T; Cook, RJ; de Botton, S; Eaton, M; Fenaux, P; Fiore, C; Hodgson, G; Jurcic, JG; Kang-Fortner, Q; Kelly, MJ; Liesveld, JL; Madigan, K; McKeown, M; Paul, S; Rizzieri, DA; Roboz, GJ; Roth, DA; Rousselot, P; Savona, MR; Sekeres, MA; Stein, EM; Stephens, K; Vigil, C; Volkert, A | 1 |
| di Tomaso, E; Fiore, C; Johannessen, L; Lee, E; McKeown, MR | 1 |
| Ishiyama, K; Kasahara, K; Nakao, S; Ohkura, N; Saeki, K; Watanabe, S | 1 |
| Asou, N; Fujita, H; Hyo, R; Inaguma, Y; Ishigatsubo, Y; Iwanaga, M; Izumi, T; Kiyoi, H; Matsuda, M; Miyawaki, S; Miyazaki, Y; Nakaseko, C; Naoe, T; Nomura, S; Ohnishi, K; Ohtake, S; Okada, M; Shinagawa, K; Takeshita, A; Yamauchi, T | 1 |
| Amano, Y; Muratake, H; Shudo, K; Sugiyama, K; Toda, T | 1 |
| Kiyoi, H | 1 |
| Feng, R; Hu, Y; Huang, G; Jiang, Y; Liu, J; Liu, X; Wang, Z; Zhang, J; Zhang, Z | 1 |
| Douer, D; Ganzel, C | 1 |
| Fujita, H | 1 |
| Allen, SL; Altman, JK; Cortes, JE; Coutre, S; Di Bona, E; Kantarjian, H; Lo-Coco, F; Ravandi, F; Sanford, D; Sanz, MA; Wetzler, M | 1 |
| Tallman, MS | 1 |
| Arcese, W; Cudillo, L; Di Veroli, A; Divona, M; Giannì, L; Giannotti, F; Lo-Coco, F; Mirabile, M; Ramadan, SM; Wieland, S | 1 |
| Anderson, LD; Collins, RH; Kirk, A; Levitt, D; Naina, HV; Scaglioni, PP; Vusirikala, M | 1 |
| Asakura, H; Nakao, S; Ohata, K; Shimadoi, S; Yamazaki, H | 1 |
| Cheng, YN; Qu, XJ; Xu, WF; Xue, X; Yuan, C; Zhang, YS | 1 |
| Inoue, A; Kawakami, C; Takitani, K; Tamai, H | 1 |
| Emi, N | 1 |
| Takahashi, K; Takeuchi, M; Yoshida, I | 1 |
| Barbarroja, N; Buendía, P; Dorado, G; López-Pedrera, C; Torres, A; Velasco, F | 1 |
| Takeuchi, M | 1 |
| Fukasawa, H; Kagechika, H; Shudo, K | 1 |
| Ohnishi, K | 2 |
| Kagechika, H; Miwako, I | 1 |
| Breitman, TR; Takahashi, N | 1 |
| Miyawaki, S; Ohnishi, K; Ohno, R; Shibata, Y; Shinjo, K; Shudo, K; Takeshita, A; Tobita, T; Yanagi, M | 1 |
| Harada, M; Kibata, M; Ohno, R; Omoto, E; Shudo, K; Takahashi, K; Takeuchi, M; Ueda, R; Yano, T | 2 |
| Hiraoka, A; Karasuno, T; Kitamura, K; Miyawaki, S; Naoe, T; Ohnishi, K; Ohno, R; Takeshita, A; Takeuchi, M; Tobita, T; Ueda, R; Yanagi, M | 1 |
| Kitamura, K; Kiyoi, H; Naoe, T; Ohno, R; Takeshita, A; Tobita, T; Yoshida, H | 1 |
| Ata, K; Fukutani, H; Hiraoka, A; Miyawaki, S; Ohnishi, K; Ohno, R; Sakura, T; Shinjo, K; Takeshita, A; Takeuchi, M; Tomoyasu, S; Ueda, R; Wakita, H | 1 |
| Chambon, P; Gaub, MP; Hashimoto, Y; Kagechika, H; Petkovich, M; Shudo, K | 1 |
10 review(s) available for tamibarotene and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
[Leukemia: recent progress in diagnosis and treatment. Topics: III. Diagnosis and treatments; 3. Treatment for acute promyelocytic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenites; Benzoates; Humans; Leukemia, Promyelocytic, Acute; Prognosis; Tetrahydronaphthalenes | 2013 |
Extramedullary disease in APL: a real phenomenon to contend with or not?
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Cerebral Hemorrhage; Humans; Incidence; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Models, Biological; Multicenter Studies as Topic; Organ Specificity; Oxides; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Risk Factors; Tetrahydronaphthalenes; Tretinoin | 2014 |
[Treatment for acute promyelocytic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Clinical Trials, Phase III as Topic; Consolidation Chemotherapy; Disseminated Intravascular Coagulation; Gene Fusion; Humans; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Molecular Targeted Therapy; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Receptors, Retinoic Acid; Recurrence; Remission Induction; Retinoic Acid Receptor alpha; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Suppressor Proteins | 2014 |
Tamibarotene: AM 80, retinobenzoic acid, Tamibaro.
Topics: Animals; Antineoplastic Agents; Benzoates; Clinical Trials as Topic; Diabetes Mellitus; Humans; Leukemia, Promyelocytic, Acute; Rheumatic Diseases; Skin Diseases; Tetrahydronaphthalenes | 2004 |
[Clinical experience with a new synthetic retinoid, tamibarotene (Am-80) for relapsed or refractory acute promyelocytic leukemia].
Topics: Benzoates; Cell Differentiation; Clinical Trials, Phase II as Topic; Drug Administration Schedule; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Pilot Projects; Recurrence; Remission Induction; Retinoids; Tetrahydronaphthalenes | 2006 |
[Retinoid therapy for autoimmune diseases].
Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Benzoates; Humans; Leukemia, Promyelocytic, Acute; Receptors, Retinoic Acid; Retinoids; Skin Diseases; T-Lymphocytes; Tetrahydronaphthalenes; Tretinoin | 2006 |
[Therapeutic strategies for patients with relapsed acute promyelocytic leukemia].
Topics: Aminoglycosides; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzoates; Clinical Trials as Topic; Combined Modality Therapy; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Hydroxamic Acids; Leukemia, Promyelocytic, Acute; Oxides; Practice Guidelines as Topic; Recurrence; Remission Induction; Tetrahydronaphthalenes; Tretinoin | 2006 |
Tamibarotene.
Topics: Animals; Antineoplastic Agents; Benzoates; Controlled Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Leukemia, Promyelocytic, Acute; Tetrahydronaphthalenes | 2007 |
PML-RARalpha inhibitors (ATRA, tamibaroten, arsenic troxide) for acute promyelocytic leukemia.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzoates; Humans; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion; Oxides; Tetrahydronaphthalenes; Tretinoin | 2007 |
Relapsed acute promyelocytic leukemia previously treated with all-trans retinoic acid: clinical experience with a new synthetic retinoid, Am-80.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenicals; Benzoates; Biomarkers, Tumor; Cheilitis; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Leukemia, Promyelocytic, Acute; Leukocytosis; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Pilot Projects; Recurrence; Remission Induction; Salvage Therapy; Tetrahydronaphthalenes; Treatment Outcome; Tretinoin; Tumor Cells, Cultured | 1998 |
5 trial(s) available for tamibarotene and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Tamibarotene in patients with acute promyelocytic leukaemia relapsing after treatment with all-trans retinoic acid and arsenic trioxide.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Biomarkers, Tumor; Cardiovascular Diseases; Cell Differentiation; Combined Modality Therapy; Consolidation Chemotherapy; Disease-Free Survival; Drug Resistance, Neoplasm; Febrile Neutropenia; Female; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Oncogene Proteins, Fusion; Oxides; Recurrence; Remission Induction; Salvage Therapy; Tetrahydronaphthalenes; Tretinoin | 2015 |
Treatment with a new synthetic retinoid, Am80, of acute promyelocytic leukemia relapsed from complete remission induced by all-trans retinoic acid.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzoates; Cell Differentiation; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Gastrointestinal Diseases; Humans; Leukemia, Promyelocytic, Acute; Leukocytosis; Male; Middle Aged; Pain; Prospective Studies; Receptors, Retinoic Acid; Recurrence; Remission Induction; Retinoic Acid Receptor gamma; Retinoids; Salvage Therapy; Tetrahydronaphthalenes; Treatment Outcome; Tretinoin | 1997 |
New retinoids and arsenic compounds for the treatment of refractory acute promyelocytic leukemia: clinical and basic studies for the next generation.
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzoates; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Oxides; Recurrence; Remission Induction; Retinoids; Tetrahydronaphthalenes; Treatment Outcome; Tumor Cells, Cultured | 1997 |
Relapsed acute promyelocytic leukemia previously treated with all-trans retinoic acid: clinical experience with a new synthetic retinoid, Am-80.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenicals; Benzoates; Biomarkers, Tumor; Cheilitis; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Leukemia, Promyelocytic, Acute; Leukocytosis; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Pilot Projects; Recurrence; Remission Induction; Salvage Therapy; Tetrahydronaphthalenes; Treatment Outcome; Tretinoin; Tumor Cells, Cultured | 1998 |
Good prognosis of patients with acute promyelocytic leukemia who achieved second complete remission (CR) with a new retinoid, Am80, after relapse from CR induced by all-trans-retinoic acid.
Topics: Adult; Aged; Antineoplastic Agents; Benzoates; Female; Follow-Up Studies; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Prognosis; Recurrence; Remission Induction; Retinoids; Tetrahydronaphthalenes; Tretinoin | 2000 |
21 other study(ies) available for tamibarotene and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Retinobenzoic acids. 4. Conformation of aromatic amides with retinoidal activity. Importance of trans-amide structure for the activity.
Topics: Amides; Benzoates; Cell Differentiation; Cell Line; Humans; Leukemia, Promyelocytic, Acute; Magnetic Resonance Spectroscopy; Molecular Structure; Retinoids; Structure-Activity Relationship | 1989 |
Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity.
Topics: Amides; Binding Sites; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Methylation; Molecular Structure; Retinoids; Structure-Activity Relationship | 1988 |
Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML.
Topics: Azacitidine; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes; Retinoic Acid Receptor alpha | 2023 |
Antitumor synergy with SY-1425, a selective RARα agonist, and hypomethylating agents in retinoic acid receptor pathway activated models of acute myeloid leukemia.
Topics: Animals; Benzoates; Cell Line, Tumor; Humans; Leukemia, Promyelocytic, Acute; Mice; Neoplasm Proteins; Retinoic Acid Receptor alpha; Signal Transduction; Tetrahydronaphthalenes; Xenograft Model Antitumor Assays | 2019 |
Tamibarotene for the Treatment of Bronchiolitis Obliterans Associated With Chronic Graft-vs-Host Disease.
Topics: Allografts; Benzoates; Biopsy; Bronchiolitis Obliterans; Chronic Disease; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Promyelocytic, Acute; Lung; Male; Middle Aged; Tetrahydronaphthalenes; Tomography, X-Ray Computed | 2019 |
Role of hematopoietic stem cell transplantation for relapsed acute promyelocytic leukemia: a retrospective analysis of JALSG-APL97.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzoates; Combined Modality Therapy; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Japan; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Oxides; Recurrence; Retrospective Studies; Salvage Therapy; Tetrahydronaphthalenes; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Tretinoin; Young Adult | 2013 |
Synthesis of Am80 (tamibarotene) prodrug candidates, congeners and metabolites.
Topics: Benzoates; Humans; Leukemia, Promyelocytic, Acute; Oxidation-Reduction; Phenylpropionates; Prodrugs; Receptors, Retinoic Acid; Tetrahydronaphthalenes | 2013 |
Novel PEG-grafted nanostructured lipid carrier for systematic delivery of a poorly soluble anti-leukemia agent Tamibarotene: characterization and evaluation.
Topics: Animals; Animals, Outbred Strains; Antineoplastic Agents; Benzoates; Blood-Brain Barrier; Drug Carriers; Drug Compounding; Drug Delivery Systems; Half-Life; Injections, Intravenous; Kidney; Lecithins; Leukemia, Promyelocytic, Acute; Mice; Nanostructures; Particle Size; Polyethylene Glycols; Random Allocation; Rats, Wistar; Solubility; Surface Properties; Tetrahydronaphthalenes; Tissue Distribution | 2015 |
Updates on the treatment of acute promyelocytic leukemia.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Benzoates; Cytarabine; Daunorubicin; Hemorrhage; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Tetrahydronaphthalenes; Tretinoin | 2010 |
Molecular remission in advanced acute promyelocytic leukaemia after treatment with the oral synthetic retinoid Tamibarotene.
Topics: Adult; Antineoplastic Agents; Benzoates; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Promyelocytic, Acute; Recurrence; Tetrahydronaphthalenes | 2010 |
Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene.
Topics: Adult; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Bone Marrow; Bone Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Resistance, Neoplasm; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Male; Mercaptopurine; Methotrexate; Oxides; Radionuclide Imaging; Remission Induction; Salvage Therapy; Sarcoma, Myeloid; Soft Tissue Neoplasms; Tetrahydronaphthalenes; Tretinoin | 2011 |
Tamibarotene-induced low-grade reversible intravascular coagulation in a patient with acute promyelocytic leukemia.
Topics: Aged; Antineoplastic Agents; Benzoates; Humans; Leukemia, Promyelocytic, Acute; Male; Tetrahydronaphthalenes; Thrombosis; Treatment Outcome | 2012 |
A112, a tamibarotene dimethylaminoethyl ester, may inhibit human leukemia cell growth more potently than tamibarotene.
Topics: Animals; Apoptosis; Benzoates; Blotting, Western; Cell Differentiation; Cell Proliferation; Female; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Mice; Mice, Inbred BALB C; Rats; Retinoids; Tetrahydronaphthalenes | 2012 |
Sustained molecular remission after arsenic trioxide and gemutuzumab ozogamicin in a pediatric patient with relapsed acute promyelocytic leukemia.
Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Arsenic Trioxide; Arsenicals; Benzoates; Child; Drug Administration Schedule; Gemtuzumab; Humans; Leukemia, Promyelocytic, Acute; Male; Oxides; Recurrence; Remission Induction; Tetrahydronaphthalenes; Tretinoin | 2012 |
[Management of relapsed acute promyelocytic leukemia].
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzoates; Brain; Humans; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Oxides; Recurrence; Tetrahydronaphthalenes | 2012 |
[Long-term follow up of re-induction with a new synthetic retinoid, Am-80, for relapse of acute promyelocytic leukemia previously treated with all-trans retinoic acid: results of 7 cases from a single institute].
Topics: Adult; Aged; Benzoates; Follow-Up Studies; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Remission Induction; Tetrahydronaphthalenes | 2003 |
Promyelocytic leukemia retinoid signaling targets regulate apoptosis,tissue factor and thrombomodulin expression.
Topics: Apoptosis; Benzoates; Cell Differentiation; Cell Line, Tumor; Flavonoids; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Retinoids; Tetrahydronaphthalenes; Thrombomodulin; Thromboplastin | 2004 |
Induction of differentiation and covalent binding to proteins by the synthetic retinoids Ch55 and Am80.
Topics: Benzoates; Cell Differentiation; Chalcone; Chalcones; Drug Synergism; Electrophoresis, Gel, Two-Dimensional; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Protein Binding; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured | 1994 |
Successful treatment of relapse of acute promyelocytic leukemia with a new synthetic retinoid, Am80.
Topics: Adult; Benzoates; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Recurrence; Remission Induction; Retinoids; Tetrahydronaphthalenes | 1996 |
Re-induction of complete remission with a new synthetic retinoid, Am-80, for relapse of acute promyelocytic leukaemia previously treated with all-trans retinoic acid.
Topics: Adult; Benzoates; Female; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Recurrence; Remission Induction; Tetrahydronaphthalenes; Tretinoin | 1997 |
The retinoic acid receptors alpha and beta are expressed in the human promyelocytic leukemia cell line HL-60.
Topics: Antibodies; Benzoates; Blotting, Western; Carrier Proteins; Chalcone; Chalcones; Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Leukemia, Promyelocytic, Acute; Molecular Weight; Receptors, Retinoic Acid; Tetrahydronaphthalenes; Tumor Cells, Cultured | 1989 |