talipexole has been researched along with Parkinson Disease in 9 studies
talipexole: dopamine receptor agonist; structure given in first source
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report sinus bradycardia induced by talipexole hydrochloride in a 65-year-old man with Parkinson disease." | 7.70 | [Sinus bradycardia induced by talipexole hydrochloride in a patient with Parkinson disease]. ( Ii, Y; Kuzuhara, S; Sakai, T, 1998) |
| "We report sinus bradycardia induced by talipexole hydrochloride in a 65-year-old man with Parkinson disease." | 3.70 | [Sinus bradycardia induced by talipexole hydrochloride in a patient with Parkinson disease]. ( Ii, Y; Kuzuhara, S; Sakai, T, 1998) |
| "Talipexole hydrochloride has been on market in Japan recently, but MAO-B inhibitors and COMT inhibitors are in final stages to wait evaluations by the governmental committee." | 2.40 | [Clinical characteristics and trends in research of Parkinson's disease and parkinsonism in Japan]. ( Yanagisawa, N, 1997) |
| " The dosage of talipexole was gradually reduced and the drug was ultimately discontinued since incomplete neuroleptic malignant syndrome was suspected." | 1.31 | [Increase in serum creatine phosphokinase following administration of talipexole hydrochloride]. ( Imai, T; Osumi, E, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamigaichi, R | 1 |
| Kubo, S | 1 |
| Ishikawa, K | 1 |
| Yokoyama, K | 1 |
| Ogaki, K | 1 |
| Usui, C | 1 |
| Hatta, K | 1 |
| Arai, H | 1 |
| Mochizuki, H | 2 |
| Hattori, N | 2 |
| Kitamura, Y | 2 |
| Yamashiro, K | 1 |
| Komine-Kobayashi, M | 1 |
| Hatano, T | 1 |
| Urabe, T | 1 |
| Iwama, Y | 1 |
| Daida, H | 1 |
| Sakai, M | 1 |
| Nakayama, T | 1 |
| Mizuno, Y | 1 |
| Yanagisawa, N | 1 |
| Kakimura, J | 1 |
| Taniguchi, T | 1 |
| Sakai, T | 1 |
| Ii, Y | 1 |
| Kuzuhara, S | 1 |
| Osumi, E | 1 |
| Imai, T | 1 |
| Herschel, M | 1 |
| Hinzen, D | 1 |
| Hornykiewicz, O | 1 |
| Kobinger, W | 1 |
| Pichler, L | 1 |
| Pifl, C | 1 |
| Schingnitz, G | 1 |
2 reviews available for talipexole and Parkinson Disease
| Article | Year |
|---|---|
[Dopaminergic neuroprotection and reconstruction of neural network tiara].
Topics: Animals; Azepines; Benzothiazoles; Brain; Dopamine; Dopamine Agonists; Embryonic Stem Cells; Humans; | 2010 |
[Clinical characteristics and trends in research of Parkinson's disease and parkinsonism in Japan].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azepines; Child; Child, Preschool; Disease Progression; | 1997 |
7 other studies available for talipexole and Parkinson Disease
| Article | Year |
|---|---|
Effective control of catatonia in Parkinson's disease by electroconvulsive therapy: a case report.
Topics: Aged; Antiparkinson Agents; Azepines; Benzothiazoles; Cabergoline; Carbidopa; Catatonia; Catechols; | 2009 |
The frequency of cardiac valvular regurgitation in Parkinson's disease.
Topics: Aged; Aortic Valve Insufficiency; Azepines; Benzothiazoles; Bromocriptine; Cabergoline; Dopamine Ago | 2008 |
Protective effect of talipexole on MPTP-treated planarian, a unique parkinsonian worm model.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Azepines; Brain; Disease Models, Animal; Dopa | 1998 |
[Sinus bradycardia induced by talipexole hydrochloride in a patient with Parkinson disease].
Topics: Acute Disease; Aged; Arrhythmia, Sinus; Azepines; Bradycardia; Dopamine Agonists; Humans; Male; Park | 1998 |
[Increase in serum creatine phosphokinase following administration of talipexole hydrochloride].
Topics: Azepines; Creatine Kinase; Dopamine Agonists; Humans; Male; Middle Aged; Neuroleptic Malignant Syndr | 2000 |
[The dopamine receptor. Target of various diseases].
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Brain; Humans; Macaca mulatta; Parkinson Disease; Prol | 1987 |
The dopamine autoreceptor agonist B-HT 920 stimulates denervated postsynaptic brain dopamine receptors in rodent and primate models of Parkinson's disease: a novel approach to treatment.
Topics: Animals; Azepines; Brain Chemistry; Drug Interactions; Ibotenic Acid; Macaca mulatta; Male; Mice; Mi | 1986 |