talipexole has been researched along with Neuroleptic Malignant Syndrome in 1 studies
talipexole: dopamine receptor agonist; structure given in first source
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dosage of talipexole was gradually reduced and the drug was ultimately discontinued since incomplete neuroleptic malignant syndrome was suspected." | 1.31 | [Increase in serum creatine phosphokinase following administration of talipexole hydrochloride]. ( Imai, T; Osumi, E, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Osumi, E | 1 |
| Imai, T | 1 |
1 other study available for talipexole and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
[Increase in serum creatine phosphokinase following administration of talipexole hydrochloride].
Topics: Azepines; Creatine Kinase; Dopamine Agonists; Humans; Male; Middle Aged; Neuroleptic Malignant Syndr | 2000 |