talipexole has been researched along with Narcolepsy in 2 studies
talipexole: dopamine receptor agonist; structure given in first source
Narcolepsy: A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Narcolepsy is a genetically determined disorder of sleep characterized by excessive daytime sleepiness and abnormal manifestations of REM sleep that affects both humans and animals." | 1.29 | Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems. ( Arrigoni, J; Ciaranello, RD; Dement, WC; Edgar, DM; Mignot, E; Nishino, S; Reid, MS; Sharp, LH; Siegel, JM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mignot, E | 2 |
| Nishino, S | 2 |
| Sharp, LH | 1 |
| Arrigoni, J | 1 |
| Siegel, JM | 1 |
| Reid, MS | 1 |
| Edgar, DM | 1 |
| Ciaranello, RD | 1 |
| Dement, WC | 1 |
| Honda, K | 1 |
| Riehl, J | 1 |
2 other studies available for talipexole and Narcolepsy
| Article | Year |
|---|---|
Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems.
Topics: Aging; Animals; Azepines; Biogenic Amines; Brain; Cataplexy; Chromosome Mapping; Crosses, Genetic; D | 1993 |
Dopamine D3 agonists into the substantia nigra aggravate cataplexy but do not modify sleep [corrected].
Topics: Animals; Arousal; Azepines; Cataplexy; Dogs; Dopamine Agonists; Electroencephalography; Electromyogr | 1999 |