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talipexole and Muscle Contraction

talipexole has been researched along with Muscle Contraction in 51 studies

talipexole: dopamine receptor agonist; structure given in first source

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
") caused dose-dependent rightward shift in the pressor dose-response curve induced by B-HT 920."1.31alpha(2)-adrenoceptor antagonist properties of OPC-28326, a novel selective peripheral vasodilator. ( Hashimoto, A; Imaizumi, T; Kambe, T; Kishi, M; Mori, T; Nakazawa, T; Orito, K, 2001)
" In all rings, cooling caused an increase in the slope of the dose-response curve and a significant increase in the concentration of agonist required to evoke contractions, as assessed by that concentration of NE required to evoke a contraction equal to 10% of maximal (EC10)."1.28Cooling augments alpha 2-adrenoceptor-mediated contractions in rat tail artery. ( Bowman, CJ; Harker, CT; Ousley, PJ; Porter, JM, 1991)
"Benextramine was equipotent against the imidazoline, clonidine and the thiazoloazepine B-HT920, however, higher concentrations of benextramine were required for an equivalent non-competitive antagonism of the beta-phenethylamine, alpha-methylnoradrenaline."1.27The action and interaction of beta-phenethylamines and imidazolines on prejunctional alpha 2-adrenoceptors of guinea-pig ileum in the presence of the non-competitive antagonist benextramine. ( Mottram, DR; Thakar, Y, 1984)
" In the rat tail artery, there were no differences in the dose-response relationships to noradrenaline, methoxamine, and KCl whether the agonists were applied as single or cumulative doses."1.27Desensitization of the vascular contractile response to cumulative doses of alpha 2-adrenoceptor agonists. ( Cheung, DW, 1986)
"Clonidine was the most potent inhibitor of the contractions, followed closely by B-HT 920."1.27Prejunctional alpha 2-adrenoceptor mediated inhibitory action of clonidine and B-HT 920, but not urapidil in guinea pig ileum. ( Shebuski, RJ; Zimmerman, BG, 1985)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199031 (60.78)18.7374
1990's15 (29.41)18.2507
2000's5 (9.80)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artigues-Varin, C1
Richard, V1
Varin, R1
Mulder, P1
Thuillez, C1
Recio, P1
Prieto, D1
Martínez, MP1
García, P1
Rivera, L1
Benedito, S1
Martínez, AC1
Sacristán, AG1
Orensanz, LM1
Hernández, M1
Corboz, MR2
Mutter, JC1
Rivelli, MA2
Mingo, GG2
McLeod, RL2
Varty, L2
Jia, Y2
Cartwright, M1
Hey, JA2
Mottram, DR2
García-Sacristán, A1
Casanueva, CR1
Castilla, C1
Labadia, A1
Macia, RA1
Matthews, WD3
Lafferty, J1
DeMarinis, RM1
Beckeringh, JJ1
Thoolen, MJ1
De Jonge, A1
Wilffert, B1
Timmermans, PB1
Van Zwieten, PA1
Thakar, Y1
Miller, RC1
Mony, M1
Schini, V1
Schoeffter, P1
Stoclet, JC2
Lues, I1
Schümann, HJ2
Su, CM1
Swamy, VC1
Triggle, DJ1
Grundström, N2
Andersson, RG2
Wikberg, JE2
Fowler, PJ1
Grous, M1
Price, W1
Visnovsky, P1
Leitch, IM1
Rawlow, A1
King, RG1
Boura, AL1
Bremner, JB1
Browne, EJ1
Oliver, JW1
Abney, LK1
Strickland, JR1
Linnabary, RD1
Sharma, A1
Kulkarni, SK1
Bryant, CE1
Clarke, KW1
Nishio, H1
Kohno, Y1
Fujii, A1
Negishi, Y1
Inoue, A1
Nakata, Y1
García-Villalón, AL1
Padilla, J1
Monge, L1
Fernández, N1
Sánchez, MA1
Gómez, B1
Diéguez, G1
Orito, K1
Kishi, M1
Imaizumi, T1
Nakazawa, T1
Hashimoto, A1
Mori, T1
Kambe, T1
Miller, VM2
Kwan, CY3
Gaspar, V1
Shi, AG2
Wang, ZL2
Chen, MC1
Ohta, A1
Cragoe, EJ2
Daniel, EE3
Guan, YY3
Chen, KM1
Sun, JJ1
Morrison, KJ1
Flavahan, NA1
Vanhoutte, PM2
Topouzis, S1
Schott, C1
Hoo, K1
Harker, CT1
Ousley, PJ1
Bowman, CJ1
Porter, JM1
Nilsson, FN1
McGregor, CG1
Barrús, MT1
Balfagón, G1
Salaíces, M1
Marín, J1
Cheung, DW3
Kazda, S1
Garthoff, B1
Knorr, A1
Haeusler, G2
de Peyer, JE2
Yajima, M1
Schultz, G1
Steinberg, MI1
Ertel, P1
Smallwood, JK1
Wyss, V1
Zimmerman, K1
Douglas, SA1
Bowmer, CJ1
Yates, MS1
Molderings, GJ1
Doggrell, SA1
Liebau, S1
Hohlfeld, J1
Förstermann, U1
Palluk, R1
Hoefke, W1
Gaida, W1
Bou, J1
Massingham, R1
Hynes, MR1
Dang, H1
Duckles, SP1
Shibata, S1
Satake, N1
Hester, RK1
Kurahashi, K1
Ito, M1
Furuta, T1
Shebuski, RJ1
Zimmerman, BG1
Jim, KF1
Jayakody, RL1
Senaratne, MP1
Kappagoda, T1

Other Studies

51 other studies available for talipexole and Muscle Contraction

ArticleYear
Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Re

2002
Immunohistochemical and functional evidence for a noradrenergic regulation in the horse penile deep dorsal vein.
    International journal of impotence research, 2004, Volume: 16, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Dopamine beta-Hydroxylas

2004
alpha2-adrenoceptor agonists as nasal decongestants.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon

2007
Mechanism of decongestant activity of alpha 2-adrenoceptor agonists.
    Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; A

2008
Pre-junctional alpha 2-adrenoceptor activity of B-HT920.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:10

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; Dioxanes; Drug Interactions; Guinea Pigs; I

1983
Adrenergic receptors in the urethra and prostate of the horse.
    Research in veterinary science, 1984, Volume: 36, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Drug Interactions; Horses; Male; Muscle Contraction; M

1984
Assessment of alpha-adrenergic receptor subtypes in isolated rat aortic segments.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Azepines; Clonidi

1984
The contractions induced in rat and guinea-pig aortic strips by the alpha 2-adrenoceptor selective agonists B-HT 920 and UK 14,304 are mediated by alpha 1-adrenoceptors.
    European journal of pharmacology, 1984, Sep-17, Volume: 104, Issue:3-4

    Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Brimonidine Tartrate; Dose-Response Relationshi

1984
The action and interaction of beta-phenethylamines and imidazolines on prejunctional alpha 2-adrenoceptors of guinea-pig ileum in the presence of the non-competitive antagonist benextramine.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Cystamine; El

1984
Endothelial mediated inhibition of contraction and increase in cyclic GMP levels evoked by the alpha-adrenoceptor agonist B-HT 920 in rat isolated aorta.
    British journal of pharmacology, 1984, Volume: 83, Issue:4

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Cyclic AMP; Cy

1984
Effect of removing the endothelial cells on the reactivity of rat aortic segments to different alpha-adrenoceptor agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 328, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Clonidine; Endothelium; Imidazoles; I

1984
Calcium channel activation in vascular smooth muscle by BAY K 8644.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:11

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1984
Inhibition of the excitatory non-adrenergic, non-cholinergic neurotransmission in the guinea pig tracheo-bronchial tree mediated by alpha 2-adrenoceptors.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:1

    Topics: Animals; Azepines; Bronchi; Cocaine; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniqu

1984
Pharmacological differentiation of postsynaptic alpha adrenoceptors in the dog saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:3

    Topics: Animals; Azepines; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthols; Nore

1984
Pharmacology of B-HT 920 in some isolated smooth muscles of the guinea-pig.
    Acta pharmacologica et toxicologica, 1982, Volume: 50, Issue:4

    Topics: Animals; Aorta; Azepines; Clonidine; Dogs; Drug Interactions; Ileum; In Vitro Techniques; Male; Musc

1982
The action of 1,2,3,5,6,11b-hexahydro-[1]benzothieno [3,2-g]indolizine hydrochloride (ADT 16) on peripheral and central responses mediated by 5-hydroxytryptaminergic and adrenergic systems of the rat.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:10

    Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Guinea Pigs; In Vitro Techniques; Indolizines; Male

1994
Vasoconstriction in bovine vasculature induced by the tall fescue alkaloid lysergamide.
    Journal of animal science, 1993, Volume: 71, Issue:10

    Topics: Adrenergic alpha-Agonists; Animals; Arteries; Azepines; Cattle; Cattle Diseases; Dose-Response Relat

1993
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation.
    Indian journal of experimental biology, 1994, Volume: 32, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipra

1994
The actions of medetomidine may not be mediated exclusively by alpha 2-adrenoceptors in the equine saphenous vein.
    Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Do

1996
5-HT3 receptor blocking properties of the antiparkinsonian agent, talipexole.
    General pharmacology, 1996, Volume: 27, Issue:5

    Topics: Animals; Azepines; Bromocriptine; Cerebral Cortex; Dopamine Antagonists; Emetics; Female; Guinea Pig

1996
Effects of vasopressin on the sympathetic contraction of rabbit ear artery during cooling.
    British journal of pharmacology, 1999, Volume: 126, Issue:3

    Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries;

1999
alpha(2)-adrenoceptor antagonist properties of OPC-28326, a novel selective peripheral vasodilator.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Azepines; Binding, Competitive; Blood Pres

2001
Selective production of endothelium-derived nitric oxide in canine femoral veins.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 2

    Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Arginine; Azepines; Calc

1991
Vascular effects of tetramethylpyrazine: direct interaction with smooth muscle alpha-adrenoceptors.
    European journal of pharmacology, 1991, May-30, Volume: 198, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amiloride; Animals; Azepines; Binding, Comp

1991
Alpha 1-adrenoceptors mediate the responses to BHT-920 and rauwolscine in dog mesenteric artery after partial depolarization by KCl.
    European journal of pharmacology, 1991, Aug-06, Volume: 200, Issue:2-3

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Calcium; Dogs; Membrane Potentials; Membranes; Mesente

1991
Differential effects of the antianginal drug nicorandil on canine arteries and veins.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Arteries; Azepines; Dinoprost; Dogs; Drug Interactions; Endothel

1990
Participation of endothelium-derived relaxing factor and role of cyclic GMP in inhibitory effects of endothelium on contractile responses elicited by alpha-adrenoceptor agonists in rat aorta.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Arginin

1991
Alpha-adrenoceptors in vascular smooth muscle: all is not well.
    Blood vessels, 1991, Volume: 28, Issue:1-3

    Topics: Amiloride; Animals; Aorta; Azepines; Cell Membrane; Dogs; Mesenteric Arteries; Mesenteric Veins; Mic

1991
Cooling augments alpha 2-adrenoceptor-mediated contractions in rat tail artery.
    The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 2

    Topics: Animals; Arteries; Azepines; Cold Temperature; Dinoprost; Male; Muscle Contraction; Muscle, Smooth,

1991
Methods of cardiac preservation alter the function of the endothelium in porcine coronary arteries.
    The Journal of thoracic and cardiovascular surgery, 1991, Volume: 102, Issue:6

    Topics: Animals; Azepines; Bicarbonates; Bradykinin; Calcimycin; Calcium Chloride; Cardioplegic Solutions; C

1991
[3H]5-hydroxytryptamine uptake and release in cat cerebral arteries.
    General pharmacology, 1990, Volume: 21, Issue:2

    Topics: Animals; Azepines; Cats; Cerebral Arteries; Cocaine; Electric Stimulation; Female; In Vitro Techniqu

1990
The effect of Bay K 8644 on contraction mediated by alpha-adrenoceptors in the rat saphenous vein.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Interference of the calcium antagonist nisoldipine with the abnormal response of vessels from hypertensive rats to alpha-adrenergic stimulation.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 6

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Hypertension; In Vitro Techniques; Male; Muscle Contra

1985
Vascular smooth muscle: availability of calcium through alpha-adrenoceptor stimulation.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 8

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Calcium; Female; Male; Methoxamine; Muscle Contraction

1986
The relation between vascular relaxant and cardiac electrophysiological effects of pinacidil.
    Journal of cardiovascular pharmacology, 1988, Volume: 12 Suppl 2

    Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Azepines; Cats; Dogs; Electrophysiology; Fema

1988
Vascular smooth muscle function in rats with acute renal failure.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Amplifying effects of several vasoconstrictor agents of alpha 1-adrenoceptor-mediated contraction of isolated thoracic aortae of the guinea pig.
    Pharmacology, 1989, Volume: 39, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Does in vitro activation of postsynaptic alpha 2-adrenoceptor utilize intracellular Ca2+ for contraction in dog saphenous vein?
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:9

    Topics: Animals; Azepines; Calcium; Dogs; Egtazic Acid; HEPES; In Vitro Techniques; Manganese; Muscle Contra

1989
The inability of the rat aorta to relax to acetylcholine does not imply lack of a functional endothelium only.
    General pharmacology, 1989, Volume: 20, Issue:4

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Azepines; Dopamine Agents; Endothelium, Vascular; Epinephri

1989
The inhibition of alpha 1-adrenoceptor-mediated contractions of rabbit pulmonary artery by Ca2+-withdrawal, pertussis toxin and N-ethylmaleimide is dependent on agonist intrinsic efficacy.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Calcium; Calcium Channel Blockers; Clonidine; Ethylmal

1989
Electrical membrane events in response to alpha-adrenoceptor stimulation.
    Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Calcium; Cell Membrane; Clonidine; Female; Male; Membr

1985
An electrophysiological study of alpha-adrenoceptor mediated excitation-contraction coupling in the smooth muscle cells of the rat saphenous vein.
    British journal of pharmacology, 1985, Volume: 84, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; Electrophysiology; In Vitro Techniques; Mal

1985
Postjunctional alpha-adrenoceptors and influence of angiotensin II in different isolated blood vessels.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Aorta; Azepines; Female; In Vitro Techniques; Ma

1985
Effect of diltiazem upon contractile responses to phenylephrine, cirazoline, Sgd 101/75, St 587 and B-HT 920 in rabbit aorta and dog saphenous vein preparations.
    European journal of pharmacology, 1986, Mar-04, Volume: 121, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Benzazepines; Clonidine; Diltiazem; D

1986
Desensitization of the vascular contractile response to cumulative doses of alpha 2-adrenoceptor agonists.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:10

    Topics: Adrenergic alpha-Agonists; Animals; Arteries; Azepines; In Vitro Techniques; Male; Methoxamine; Musc

1986
Contractile responses to adrenergic nerve stimulation are enhanced with removal of endothelium in rat caudal artery.
    Life sciences, 1988, Volume: 42, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Electric Stimulation; Endothelium, Vascular; Hydroxydo

1988
The mode of vasoinhibitory action of a pyridazione derivative (MCI-154), a new cardiotonic agent, on contractile responses induced by alpha-adrenoceptor agonists and 45Ca influx in isolated vascular smooth muscles.
    European journal of pharmacology, 1988, Jan-12, Volume: 145, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Calcium; Calcium Radioisotopes; Cardi

1988
Precontraction-induced contractile response of isolated canine portal vein to alpha-2 adrenoceptor agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Calcimycin; Cats; Clonidine; Female; In Vitro Techniqu

1988
Prejunctional alpha 2-adrenoceptor mediated inhibitory action of clonidine and B-HT 920, but not urapidil in guinea pig ileum.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 178, Issue:1

    Topics: Animals; Azepines; Clonidine; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques;

1985
Role of extracellular calcium in contractions produced by activation of postsynaptic alpha-2 adrenoceptors in the canine saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:1

    Topics: Animals; Azepines; Calcium; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Mal

1985
Effects of nicardipine and diltiazem on alpha-adrenoceptor responses in canine saphenous veins.
    European journal of pharmacology, 1987, Apr-29, Volume: 136, Issue:3

    Topics: Animals; Azepines; Diltiazem; Dogs; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contracti

1987