tak-475 has been researched along with Dyslipidemias* in 1 studies
1 other study(ies) available for tak-475 and Dyslipidemias
Article | Year |
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Squalene synthase inhibition: a novel target for the management of dyslipidemia.
A new class of compounds, known as squalene synthase inhibitors, has recently reached phase III clinical trials and may provide another therapeutic option for clinicians to improve risk management of low-density lipoprotein cholesterol (LDL-C). The clinical need for another LDL-C-lowering therapy is evident by the inability to achieve an LDL-C target of less than 70 mg/dL in the majority of very high-risk patients on statin monotherapy. Human clinical trial data with TAK-475, a novel and potent inhibitor of squalene synthase, have not yet been published. Topics: Clinical Trials, Phase III as Topic; Drug Delivery Systems; Dyslipidemias; Farnesyl-Diphosphate Farnesyltransferase; Humans; Oxazepines; Piperidines | 2007 |