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tadalafil and Scleroderma, Systemic

tadalafil has been researched along with Scleroderma, Systemic in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (14.29)29.6817
2010's7 (50.00)24.3611
2020's5 (35.71)2.80

Authors

AuthorsStudies
Baniotopoulos, P; Dimitroulas, T; Hatzichristodoulou, G; Minopoulou, I; Pyrgidis, N; Sokolakis, I; Tishukov, M2
Fernández-Codina, A; Kazem, M; Pope, JE1
Blair, C; Coghlan, JG; Kuwana, M; Langley, J; Takahashi, T1
Amiya, E; Asano, Y; Hatano, M; Komuro, I; Kubota, K; Maki, H; Minatsuki, S; Morita, H; Sato, S; Yoshizaki, A1
Nikpour, M; Proudman, SM; Stevens, WM; Thakkar, V1
Chin, K; Corona-Villalobos, CP; Damico, R; Gashouta, MA; Girgis, RE; Hassoun, PM; Housten, T; Hulme, OL; Khair, R; Kolb, TM; Lechtzin, N; Mathai, SC; Minai, OA; Pisanello, C; Pullins, EH; Sato, T; Tedford, RJ; Torres, F; Zamanian, RT; Zimmerman, SL1
Khanna, D; McLaughlin, V1
Cheong, FY; Farber, HW; Gower, AC1
Barberà, JA; Blair, C; Coghlan, JG; Frost, AE; Galiè, N; Ghofrani, HA; Gillies, H; Harris, JHN; Hoeper, MM; Kuwana, M; Langley, J; McLaughlin, VV; Miller, KL; Peacock, AJ; Rubin, LJ; Simonneau, G; Vachiéry, JL1
Hsu, VM; Impens, AJ; McCloskey, DA; Phillips, K; Rothman, JA; Schiopu, E; Seibold, JR; Wilson, JE1
Agarwal, V; Choudhary, SK; Jha, LK; Kumar, S; Misra, R; Shenoy, PD; Singh, U1
Nagle, DJ; Patel, RM1
Aversa, A; Bruzziches, R; Letizia, C; Menghi, G; Merla, A; Proietti, M; Rossi, C; Salsano, F; Spera, G1

Reviews

3 review(s) available for tadalafil and Scleroderma, Systemic

ArticleYear
Treatment of Sexual Dysfunction in Women with Systemic Autoimmune Rheumatic Disorders: A Systematic Review.
    Sexual medicine reviews, 2022, Volume: 10, Issue:4

    Topics: Androgens; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Humans; Lubricants; Lupus Erythematosus, Systemic; Scleroderma, Systemic; Sexual Dysfunction, Physiological; Tadalafil; Testosterone

2022
Treatment of Sexual Dysfunction in Women with Systemic Autoimmune Rheumatic Disorders: A Systematic Review.
    Sexual medicine reviews, 2022, 10-01, Volume: 10, Issue:4

    Topics: Androgens; Female; Humans; Lupus Erythematosus, Systemic; Scleroderma, Systemic; Sexual Dysfunction, Physiological; Tadalafil

2022
Prospects for improving outcomes in systemic sclerosis-related pulmonary hypertension.
    Internal medicine journal, 2015, Volume: 45, Issue:3

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Scleroderma, Systemic; Tadalafil; Treatment Outcome

2015

Trials

5 trial(s) available for tadalafil and Scleroderma, Systemic

ArticleYear
Initial combination therapy of ambrisentan and tadalafil in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) in the modified intention-to-treat population of the AMBITION study: post hoc analysis.
    Annals of the rheumatic diseases, 2020, Volume: 79, Issue:5

    Topics: Adult; Comorbidity; Connective Tissue Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Male; Middle Aged; Phenylpropionates; Proportional Hazards Models; Pulmonary Arterial Hypertension; Pyridazines; Risk Assessment; Scleroderma, Systemic; Tadalafil; Treatment Outcome; Vasodilator Agents

2020
Initial combination therapy with ambrisentan and tadalafil in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH): subgroup analysis from the AMBITION trial.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:7

    Topics: Adult; Aged; Antihypertensive Agents; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hypertension, Pulmonary; Lupus Erythematosus, Systemic; Male; Middle Aged; Mixed Connective Tissue Disease; Phenylpropionates; Phosphodiesterase 5 Inhibitors; Pyridazines; Scleroderma, Systemic; Tadalafil

2017
Randomized placebo-controlled crossover trial of tadalafil in Raynaud's phenomenon secondary to systemic sclerosis.
    The Journal of rheumatology, 2009, Volume: 36, Issue:10

    Topics: Adult; Carbolines; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Middle Aged; Phosphodiesterase Inhibitors; Pilot Projects; Prospective Studies; Raynaud Disease; Scleroderma, Systemic; Tadalafil; Treatment Outcome

2009
Efficacy of tadalafil in secondary Raynaud's phenomenon resistant to vasodilator therapy: a double-blind randomized cross-over trial.
    Rheumatology (Oxford, England), 2010, Volume: 49, Issue:12

    Topics: Adult; Carbolines; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Raynaud Disease; Scleroderma, Systemic; Tadalafil; Treatment Outcome; Vasodilator Agents; Young Adult

2010
Erectile dysfunction in systemic sclerosis: effects of longterm inhibition of phosphodiesterase type-5 on erectile function and plasma endothelin-1 levels.
    The Journal of rheumatology, 2007, Volume: 34, Issue:8

    Topics: Adult; Carbolines; Disease Progression; Endothelin-1; Erectile Dysfunction; Health Surveys; Humans; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Scleroderma, Systemic; Tadalafil

2007

Other Studies

6 other study(ies) available for tadalafil and Scleroderma, Systemic

ArticleYear
Possible benefit of tadalafil cream for the treatment of Raynaud's phenomenon and digital ulcers in systemic sclerosis.
    Clinical rheumatology, 2020, Volume: 39, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Female; Fingers; Humans; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Raynaud Disease; Scleroderma, Systemic; Skin Cream; Tadalafil; Ulcer

2020
Characteristics of Pulmonary Arterial Hypertension in Patients with Systemic Sclerosis and Anticentriole Autoantibodies.
    International heart journal, 2020, Volume: 61, Issue:2

    Topics: Aged; Aged, 80 and over; Antibodies, Antinuclear; Autoantibodies; Bosentan; Cardiac Catheterization; Centrioles; Drug Therapy, Combination; Endothelin Receptor Antagonists; Epoprostenol; Female; Forced Expiratory Volume; Humans; Imatinib Mesylate; Protein Kinase Inhibitors; Pulmonary Arterial Hypertension; Pulmonary Diffusing Capacity; Pyrimidines; Scleroderma, Systemic; Sildenafil Citrate; Sulfonamides; Tadalafil; Tomography, X-Ray Computed; Vasodilator Agents

2020
Ambrisentan and Tadalafil Up-front Combination Therapy in Scleroderma-associated Pulmonary Arterial Hypertension.
    American journal of respiratory and critical care medicine, 2015, Nov-01, Volume: 192, Issue:9

    Topics: Drug Therapy, Combination; Female; Heart Ventricles; Humans; Hypertension, Pulmonary; Magnetic Resonance Imaging; Male; Middle Aged; Natriuretic Peptide, Brain; Phenylpropionates; Phosphodiesterase 5 Inhibitors; Prospective Studies; Pyridazines; Scleroderma, Systemic; Stroke Volume; Tadalafil; Ultrasonography; Vascular Resistance

2015
Screening and Early Detection of Pulmonary Arterial Hypertension in Connective Tissue Diseases. It Is Time to Institute It!
    American journal of respiratory and critical care medicine, 2015, Nov-01, Volume: 192, Issue:9

    Topics: Female; Humans; Hypertension, Pulmonary; Male; Phenylpropionates; Pyridazines; Scleroderma, Systemic; Tadalafil

2015
Changes in gene expression profiles in patients with pulmonary arterial hypertension associated with scleroderma treated with tadalafil.
    Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4

    Topics: Aged; Down-Regulation; Extracellular Matrix; Female; Golgi Apparatus; Humans; Hypertension, Pulmonary; Immunity, Innate; Interleukin-12; Male; Microarray Analysis; Middle Aged; Natriuretic Peptide, Brain; Phosphodiesterase 5 Inhibitors; Pilot Projects; Potassium Channels, Voltage-Gated; Scleroderma, Systemic; Signal Transduction; Tadalafil; Transcriptome; Treatment Outcome; Up-Regulation; Walk Test

2017
Nonoperative management of scleroderma of the hand with tadalafil and subatmospheric pressure wound therapy: case report.
    The Journal of hand surgery, 2012, Volume: 37, Issue:4

    Topics: Adult; Carbolines; Combined Modality Therapy; Hand; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Negative-Pressure Wound Therapy; Phosphodiesterase 5 Inhibitors; Scleroderma, Systemic; Tadalafil; Wound Healing

2012