Page last updated: 2024-09-02

tadalafil and Muscular Dystrophy, Duchenne

tadalafil has been researched along with Muscular Dystrophy, Duchenne in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Cox, D; Dieye, I; Goemans, N; Hossain, I; Jenkins, M; Landry, J; Sajeev, G; Signorovitch, J; Van den Hauwe, M; Ward, SJ; Wong, B; Yao, Z1
Byrne, B; Cox, D; Dubrovsky, AL; Eagle, M; Elashoff, R; Finkel, R; Furlong, P; Goemans, N; Landry, J; McDonald, CM; Miceli, MC; Sweeney, HL; Topaloglu, H; Vandenborne, K; Victor, RG1
Elashoff, RM; Miceli, MC; Nelson, MD; Nelson, SF; Rader, F; Sweeney, HL; Tang, X; Tavyev, J; Victor, RG1
Corbi, N; De Arcangelis, V; Di Certo, MG; Gabanella, F; Luvisetto, S; Magrelli, A; Mattei, E; Monaco, L; Naro, F; Onori, A; Passananti, C; Pisani, C; Rome, S; Severini, C; Strimpakos, G1
Forbes, SC; Hammers, DW; Shima, A; Sleeper, MM; Sweeney, HL; Walter, GA1
Anene, F; Barresi, R; Byrne, BJ; Elashoff, RM; Gurudevan, SV; Martin, EA; Scott, BL; Thomas, GD; Tsimerinov, EI; Victor, RG; Walker, AE1

Trials

4 trial(s) available for tadalafil and Muscular Dystrophy, Duchenne

ArticleYear
Prognostic factors for changes in the timed 4-stair climb in patients with Duchenne muscular dystrophy, and implications for measuring drug efficacy: A multi-institutional collaboration.
    PloS one, 2020, Volume: 15, Issue:6

    Topics: Adolescent; Child; Computer Simulation; Disease Progression; Exercise Test; Follow-Up Studies; Humans; Male; Muscular Dystrophy, Duchenne; Neuromuscular Agents; Prognosis; Sample Size; Tadalafil; Walking

2020
A phase 3 randomized placebo-controlled trial of tadalafil for Duchenne muscular dystrophy.
    Neurology, 2017, Oct-24, Volume: 89, Issue:17

    Topics: Adolescent; Area Under Curve; Child; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Glucocorticoids; Heart Rate; Humans; International Cooperation; Male; Muscular Dystrophy, Duchenne; Quality of Life; Respiratory Function Tests; Tadalafil; Treatment Outcome; Vasodilator Agents; Ventricular Function, Left; Walking

2017
PDE5 inhibition alleviates functional muscle ischemia in boys with Duchenne muscular dystrophy.
    Neurology, 2014, Jun-10, Volume: 82, Issue:23

    Topics: Adolescent; Carbolines; Child; Exercise; Forearm; Humans; Ischemia; Male; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Sildenafil Citrate; Spectroscopy, Near-Infrared; Sulfones; Sympathetic Nervous System; Tadalafil; Ultrasonography; Vasoconstriction

2014
Tadalafil alleviates muscle ischemia in patients with Becker muscular dystrophy.
    Science translational medicine, 2012, Nov-28, Volume: 4, Issue:162

    Topics: Adolescent; Adult; Animals; Biopsy; Carbolines; Child; Child, Preschool; Humans; Immunohistochemistry; Ischemia; Male; Mice; Middle Aged; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Phosphodiesterase 5 Inhibitors; Sympatholytics; Tadalafil; Young Adult

2012

Other Studies

2 other study(ies) available for tadalafil and Muscular Dystrophy, Duchenne

ArticleYear
Pathways Implicated in Tadalafil Amelioration of Duchenne Muscular Dystrophy.
    Journal of cellular physiology, 2016, Volume: 231, Issue:1

    Topics: Animals; Female; Lipid Metabolism; Male; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphodiesterase 5 Inhibitors; Tadalafil; Transcription Factors; Up-Regulation

2016
Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts.
    Journal of the American Heart Association, 2016, 08-09, Volume: 5, Issue:8

    Topics: Animals; Cardiomyopathies; Cardiotonic Agents; Disease Models, Animal; Dogs; Dystrophin; Echocardiography; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Tadalafil; TRPC6 Cation Channel

2016