Page last updated: 2024-09-02

tadalafil and Diabetes Mellitus, Type 2

tadalafil has been researched along with Diabetes Mellitus, Type 2 in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's9 (56.25)24.3611
2020's4 (25.00)2.80

Authors

AuthorsStudies
Aoki, Y; Inamura, S; Ito, H; Kobayashi, H; Nagase, K; Taga, M; Yokoyama, O; Zha, X1
Badagliacca, R; Barbagallo, F; Barbano, B; Caboni, P; Campolo, F; Carbone, I; Catalano, C; Ciolina, F; Defeudis, G; Feola, T; Filardi, T; Francone, M; Galea, N; Gianfrilli, D; Giannetta, E; Isidori, AM; Lenzi, A; Minnetti, M; Pasqualetti, P; Pofi, R; Pozzilli, P; Sesti, F; Venneri, MA; Vizza, CD1
Das, A; Koka, S; Kukreja, RC; Samidurai, A; Wang, R; Xi, L1
Bayar, G; Salman, MY; Yavuz, A; Yıldırım, Ç1
Aluri, HS; Koka, S; Kukreja, RC; Lesnefsky, EJ; Xi, L1
Angulo, J; Cardoso, J; Cuevas, P; Fernández, A; La Fuente, JM; Martínez-Salamanca, JI; Wright, HM1
Fogelstrand, P; Jansson, PA; Mattsson Hultén, L; Mobini, R; Olausson, J; Sjögren, L; Strindberg, L1
Chopp, M; Jia, L; Lu, M; Lu, X; Szalad, A; Wang, L; Zhang, RL; Zhang, ZG1
Jansson, PA; Lönnroth, P; Murdolo, G; Nyström, B; Sjögren, L; Sjöstrand, M; Strindberg, L1
Koka, S; Kukreja, RC; Xi, L1
Jansson, PA; Lönnroth, P; Murdolo, G; Sjöstrand, M; Strindberg, L1
Asadolahzade, A; Esmaeili, S; Farzan, A; Hamidi Madani, A; Mokhtari, G; Shahrokhi Damavand, R1
Das, A; Koka, S; Kukreja, RC; Salloum, FN1
Anglin, G; Emmick, JT; Knight, JR; Sáenz de Tejada, I1
Calogero, AE; Cannizzaro, MA; Condorelli, R; La Vignera, S; Noto, Z; Vicari, E1
Brock, GB; Buvat, J; Gambla, M; Hatzichristou, D; Liang, S; Lording, D; Rose, L; Rubio-Aurioles, E; Spera, G1

Reviews

1 review(s) available for tadalafil and Diabetes Mellitus, Type 2

ArticleYear
Treating diabetes with combination of phosphodiesterase 5 inhibitors and hydroxychloroquine-a possible prevention strategy for COVID-19?
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:3

    Topics: Animals; COVID-19; COVID-19 Drug Treatment; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hydroxychloroquine; Hyperglycemia; Insulin Resistance; Male; Mice; Myocardial Infarction; Phosphodiesterase 5 Inhibitors; Sildenafil Citrate; Tadalafil; Vardenafil Dihydrochloride

2023

Trials

8 trial(s) available for tadalafil and Diabetes Mellitus, Type 2

ArticleYear
Sex-specific effects of daily tadalafil on diabetic heart kinetics in RECOGITO, a randomized, double-blind, placebo-controlled trial.
    Science translational medicine, 2022, 06-15, Volume: 14, Issue:649

    Topics: Carbolines; Cyclic Nucleotide Phosphodiesterases, Type 5; Diabetes Mellitus, Type 2; Double-Blind Method; Erectile Dysfunction; Female; Humans; Kinetics; Male; MicroRNAs; Penile Erection; Phosphodiesterase 5 Inhibitors; Tadalafil; Treatment Outcome; Ventricular Remodeling

2022
Comparison of three different tadalafil regimens for erectile dysfunction treatment in patients with diabetes mellitus microvascular complications.
    Andrologia, 2022, Volume: 54, Issue:10

    Topics: Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Erectile Dysfunction; Humans; Male; Reproducibility of Results; Tadalafil; Treatment Outcome

2022
Postprandial effects of the phosphodiesterase-5 inhibitor tadalafil in people with well-controlled Type 2 diabetes mellitus: a randomized controlled trial.
    Diabetic medicine : a journal of the British Diabetic Association, 2016, Volume: 33, Issue:9

    Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Endothelial Cells; Female; Forearm; Humans; Insulin Resistance; Male; Meals; Middle Aged; Phosphodiesterase 5 Inhibitors; Postprandial Period; Regional Blood Flow; Tadalafil; Treatment Outcome

2016
The selective phosphodiesterase-5 inhibitor tadalafil induces microvascular and metabolic effects in type 2 diabetic postmenopausal females.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:1

    Topics: Adipose Tissue; Body Composition; Carbolines; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Microdialysis; Microvessels; Middle Aged; Muscle, Skeletal; Neovascularization, Pathologic; Phosphodiesterase 5 Inhibitors; Postmenopause; Substrate Specificity; Tadalafil

2013
Assessment of the efficacy of combination therapy with folic acid and tadalafil for the management of erectile dysfunction in men with type 2 diabetes mellitus.
    The journal of sexual medicine, 2013, Volume: 10, Issue:4

    Topics: Adult; Aged; Carbolines; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Erectile Dysfunction; Folic Acid; Humans; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Tadalafil; Vitamin B Complex

2013
Effects of tadalafil on erectile dysfunction in men with diabetes.
    Diabetes care, 2002, Volume: 25, Issue:12

    Topics: Antihypertensive Agents; Carbolines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Erectile Dysfunction; Glycated Hemoglobin; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Placebos; Tadalafil; Treatment Outcome

2002
Tadalafil and modifications in peak systolic velocity (Doppler spectrum dynamic analysis) in the cavernosal arteries of patients with type 2 diabetes after continuous tadalafil treatment.
    Minerva endocrinologica, 2006, Volume: 31, Issue:4

    Topics: Aged; Alprostadil; Arteries; Attitude to Health; Blood Flow Velocity; Carbolines; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Administration Schedule; Erectile Dysfunction; Humans; Injections; Luteinizing Hormone; Male; Middle Aged; Nitric Oxide; Penis; Prolactin; Surveys and Questionnaires; Tadalafil; Testosterone; Treatment Outcome; Vasodilator Agents

2006
Efficacy of tadalafil once daily in men with diabetes mellitus and erectile dysfunction.
    Diabetic medicine : a journal of the British Diabetic Association, 2008, Volume: 25, Issue:2

    Topics: Adult; Aged; Carbolines; Coitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erectile Dysfunction; Humans; Male; Middle Aged; Patient Satisfaction; Phosphodiesterase Inhibitors; Severity of Illness Index; Tadalafil; Treatment Outcome

2008

Other Studies

7 other study(ies) available for tadalafil and Diabetes Mellitus, Type 2

ArticleYear
Phosphodiesterase 5 inhibitor suppresses prostate weight increase in type 2 diabetic rats.
    Life sciences, 2022, Jun-01, Volume: 298

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin-Like Growth Factor I; Male; Phosphodiesterase 5 Inhibitors; Prostate; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Tadalafil; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Weight Gain

2022
Chronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling.
    American journal of physiology. Heart and circulatory physiology, 2014, Jun-01, Volume: 306, Issue:11

    Topics: Animals; Carbolines; Diabetes Mellitus, Type 2; Heart; Mice; Mitochondria; Myocardium; Nitric Oxide; Oxidative Phosphorylation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphodiesterase 5 Inhibitors; Signal Transduction; Sirtuin 1; Tadalafil; Transcription Factors

2014
Nebivolol potentiates the efficacy of PDE5 inhibitors to relax corpus cavernosum and penile arteries from diabetic patients by enhancing the NO/cGMP pathway.
    The journal of sexual medicine, 2014, Volume: 11, Issue:5

    Topics: Arteries; Benzopyrans; Carbolines; Cyclic GMP; Diabetes Mellitus, Type 2; Drug Synergism; Erectile Dysfunction; Ethanolamines; Humans; Imidazoles; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nebivolol; Nitric Oxide; Penile Erection; Penis; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents

2014
Tadalafil Promotes the Recovery of Peripheral Neuropathy in Type II Diabetic Mice.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Models, Animal; Gene Expression Regulation; Humans; Lymphokines; Mice; Mice, Inbred NOD; Motor Activity; Nerve Fibers; Nerve Growth Factor; Peripheral Nervous System Diseases; Platelet-Derived Growth Factor; Sciatic Nerve; Tadalafil

2016
Tadalafil increases muscle capillary recruitment and forearm glucose uptake in women with type 2 diabetes.
    Diabetologia, 2010, Volume: 53, Issue:10

    Topics: Aged; Area Under Curve; Capillaries; Carbolines; Diabetes Mellitus, Type 2; Female; Forearm; Glucose; Humans; Linear Models; Microdialysis; Middle Aged; Phosphodiesterase Inhibitors; Regional Blood Flow; Tadalafil

2010
Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts.
    Basic research in cardiology, 2012, Volume: 107, Issue:2

    Topics: Animals; Blotting, Western; Carbolines; Cytoskeleton; Diabetes Mellitus, Type 2; Electrophoresis, Gel, Two-Dimensional; Heart; Male; Mice; Mice, Inbred C57BL; Myocardium; Oxidation-Reduction; Phosphodiesterase 5 Inhibitors; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tadalafil; Ventricular Function, Left

2012
Phosphodiesterase-5 inhibitor tadalafil attenuates oxidative stress and protects against myocardial ischemia/reperfusion injury in type 2 diabetic mice.
    Free radical biology & medicine, 2013, Volume: 60

    Topics: Animals; Apoptosis; Carbolines; Cardiotonic Agents; Cyclic Nucleotide Phosphodiesterases, Type 5; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Mice; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Reactive Oxygen Species; Tadalafil

2013