Page last updated: 2024-09-02

tadalafil and Cardiac Failure

tadalafil has been researched along with Cardiac Failure in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's8 (53.33)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Andrade, DR; Claudino, MA; Goncalves, TT; Janussi, SC; Krikorian, K; Mora, AG; Priviero, FBM1
Adel, FW; Benike, SL; Burnett, JC; Chen, HH; Hubers, SA; Scott, C; Wan, SH1
Cockrill, BA; Ruopp, NF1
Skoularigis, J; Starling, RC; Triposkiadis, F; Xanthopoulos, A1
Fukumoto, Y; Inoguchi, N; Itaya, N; Kono, S; Kumanomido, J; Nakayoshi, T; Nohara, S; Shimozono, K; Takahashi, J1
Beitzke, D; Bouchardy, J; Buechel, RR; Engel, R; Freese, M; Frenk, A; Gabriel, H; Greutmann, M; Haaf, P; Heg, D; Mueller, C; Possner, M; Ruperti-Repilado, FJ; Rutz, T; Schwerzmann, M; Schwitter, J; Schwitz, F; Tobler, D; Trachsel, L; Valsangiacomo Buechel, E; Willhelm, M; Wustmann, K1
Baldus, S; Dumitrescu, D; Gerhardt, F; Hellmich, M; Kramer, T; Orlova, K; Rosenkranz, S; Ten Freyhaus, H1
Becker, LK; Caldwell, JL; Church, SJ; Dibb, KM; Eisner, DA; Hutchings, DC; Kirkwood, GJ; Lawless, M; Madders, GWP; Pearman, CM; Radcliffe, EJ; Smith, CER; Taylor, RF; Trafford, AW; Unwin, RD; Woods, LS1
Chau, VQ; Hoke, NN; Kukreja, RC; Salloum, FN1
Burgoyne, JR; Eaton, P; Grover, S; Kass, D; Prysyazhna, O; Scotcher, J1
Banasiak, W; Inorowicz, E; Jankowska, EA; Josiak, K; Kremis, E; Ponikowski, P1
Aizawa, T; Hatano, M; Inaba, T; Kinugawa, K; Maki, H; Nagai, R; Shiga, T; Yamashita, T; Yao, A1
Abassi, Z; Abu-Saleh, N; Armaly, Z; Aronson, D; Assady, S; Awad, H; Bishara, B; Ghrayeb, N; Goltsman, I; Haddad, E; Haddad, S; Khamaysi, I1
Kass, DA1
Kukreja, RC1

Reviews

4 review(s) available for tadalafil and Cardiac Failure

ArticleYear
Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review.
    JAMA, 2022, 04-12, Volume: 327, Issue:14

    Topics: Adult; Antihypertensive Agents; Endothelin Receptor Antagonists; Endothelins; Guanosine Monophosphate; Heart Failure; Humans; Hypertension, Pulmonary; Infant, Newborn; Nitric Oxide; Pulmonary Arterial Hypertension; Tadalafil; United States

2022
Therapeutic augmentation of NO-sGC-cGMP signalling: lessons learned from pulmonary arterial hypertension and heart failure.
    Heart failure reviews, 2022, Volume: 27, Issue:6

    Topics: Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Guanosine Monophosphate; Guanylate Cyclase; Heart Failure; Humans; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Pulmonary Arterial Hypertension; Retrospective Studies; Sildenafil Citrate; Soluble Guanylyl Cyclase; Tadalafil; Vasodilator Agents

2022
[Is there a place for treatment with type 5 phosphodiesterase inhibitors in heart failure patients?].
    Kardiologia polska, 2011, Volume: 69, Issue:9

    Topics: Carbolines; Heart Failure; Humans; Imidazoles; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Randomized Controlled Trials as Topic; Sildenafil Citrate; Sulfones; Tadalafil; Treatment Outcome; Triazines; Vardenafil Dihydrochloride

2011
Cardiac role of cyclic-GMP hydrolyzing phosphodiesterase type 5: from experimental models to clinical trials.
    Current heart failure reports, 2012, Volume: 9, Issue:3

    Topics: Carbolines; Cardiomyopathy, Dilated; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Fibrosis; Heart; Heart Failure; Humans; Hypertrophy; Myocardium; Phosphodiesterase 5 Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Transforming Growth Factor beta; TRPC Cation Channels; Ventricular Remodeling

2012

Trials

2 trial(s) available for tadalafil and Cardiac Failure

ArticleYear
Cardiorenal Effects of Long-Term Phosphodiesterase V Inhibition in Pre-Heart Failure.
    Journal of the American Heart Association, 2022, 01-18, Volume: 11, Issue:2

    Topics: Animals; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Glomerular Filtration Rate; Heart Failure; Humans; Natriuretic Peptide, Brain; Sodium; Tadalafil

2022
Effect of phosphodiesterase-5 inhibition on SystEmic Right VEntricular size and function. A multicentre, double-blind, randomized, placebo-controlled trial: SERVE.
    European journal of heart failure, 2023, Volume: 25, Issue:7

    Topics: Adult; Cyclic Nucleotide Phosphodiesterases, Type 5; Double-Blind Method; Female; Heart Failure; Heart Ventricles; Humans; Middle Aged; Stroke Volume; Tadalafil; Transposition of Great Vessels; Ventricular Function, Right

2023

Other Studies

9 other study(ies) available for tadalafil and Cardiac Failure

ArticleYear
Tadalafil treatment improves cardiac, renal and lower urinary tract dysfunctions in rats with heart failure.
    Life sciences, 2022, Jan-15, Volume: 289

    Topics: Animals; Heart Failure; Kidney; Lower Urinary Tract Symptoms; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tadalafil; Urinary Bladder

2022
Effects of Low-Dose Tadalafil in a Patient with Biventricular Heart Failure: A Case Report.
    The Tohoku journal of experimental medicine, 2023, May-20, Volume: 260, Issue:1

    Topics: Aged; Cardiac Output, Low; Heart Failure; Hemodynamics; Humans; Male; Phosphodiesterase 5 Inhibitors; Tadalafil

2023
Therapeutic potential of phosphodiesterase type 5 inhibitors in heart failure with preserved ejection fraction and combined post- and pre-capillary pulmonary hypertension.
    International journal of cardiology, 2019, 05-15, Volume: 283

    Topics: Aged; Cardiac Catheterization; Echocardiography; Female; Follow-Up Studies; Heart Failure; Heart Ventricles; Humans; Hypertension, Pulmonary; Male; Phosphodiesterase 5 Inhibitors; Retrospective Studies; Stroke Volume; Tadalafil; Time Factors; Treatment Outcome; Vascular Resistance; Ventricular Function, Right

2019
Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.
    Scientific reports, 2019, 05-01, Volume: 9, Issue:1

    Topics: Animals; Catecholamines; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Female; Heart Failure; Induced Pluripotent Stem Cells; Myocardial Contraction; Myocytes, Cardiac; Phosphodiesterase 5 Inhibitors; Sheep; Tadalafil; Ventricular Remodeling

2019
Tadalafil prevents acute heart failure with reduced ejection fraction in mice.
    Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:6

    Topics: Animals; Apoptosis; Carbolines; Cardiomegaly; Cardiomyopathies; Coronary Vessels; Heart Failure; Male; Mice; Mice, Inbred ICR; Myocardial Infarction; Phosphodiesterase Inhibitors; Pulmonary Edema; Tadalafil; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2014
Phosphodiesterase 5 Inhibition Limits Doxorubicin-induced Heart Failure by Attenuating Protein Kinase G Iα Oxidation.
    The Journal of biological chemistry, 2016, 08-12, Volume: 291, Issue:33

    Topics: Animals; Cardiomegaly; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic Nucleotide Phosphodiesterases, Type 5; Disulfides; Doxorubicin; Heart Failure; Mice; Mice, Mutant Strains; Oxidation-Reduction; Phosphodiesterase 5 Inhibitors; rho-Associated Kinases; Second Messenger Systems; Tadalafil

2016
Initial and programmed combination therapy with oral drugs for severe idiopathic pulmonary arterial hypertension.
    International heart journal, 2011, Volume: 52, Issue:5

    Topics: Administration, Oral; Antihypertensive Agents; Bosentan; Carbolines; Cardiac Output; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Echocardiography; Electrocardiography; Epoprostenol; Female; Heart Failure; Hemodynamics; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Middle Aged; Sulfonamides; Tadalafil; Vasodilator Agents

2011
Phosphodiesterase 5 inhibition protects against increased intra-abdominal pressure-induced renal dysfunction in experimental congestive heart failure.
    European journal of heart failure, 2012, Volume: 14, Issue:10

    Topics: Animals; Carbolines; Cardio-Renal Syndrome; Disease Models, Animal; Glomerular Filtration Rate; Heart Failure; Hemodynamics; Intra-Abdominal Hypertension; Kidney; Male; Phosphodiesterase 5 Inhibitors; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Renal Plasma Flow; Tadalafil

2012
Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthase.
    British journal of pharmacology, 2007, Volume: 150, Issue:5

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antihypertensive Agents; Carbolines; Cardiomyopathies; Cardiovascular Agents; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Doxorubicin; Endothelium, Vascular; Enzyme Inhibitors; Erectile Dysfunction; Heart Failure; Humans; Hypertension; Hypertension, Pulmonary; Imidazoles; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents; Ventricular Remodeling

2007