tacrolimus and Uterine-Neoplasms

tacrolimus has been researched along with Uterine-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for tacrolimus and Uterine-Neoplasms

ArticleYear
Treatment with ulipristal acetate (Esmya(®)) and plasma levels of tacrolimus: a case report.
    European journal of obstetrics, gynecology, and reproductive biology, 2016, Volume: 203

    Topics: Adult; Cholangitis; Drug Interactions; Female; Humans; Hysterectomy; Immunosuppressive Agents; Leiomyomatosis; Liver Transplantation; Mycophenolic Acid; Norpregnadienes; Tacrolimus; Treatment Outcome; Uterine Neoplasms

2016
Selective impairment of taurine transport by cyclosporin A in a human placental cell line.
    Pediatric research, 1992, Volume: 32, Issue:1

    We investigated, using a human placental choriocarcinoma cell line as a model, the effects of the immunosuppressive drug cyclosporin A on several placental transport systems mediating the transfer of glucose and amino acids from mother to fetus. The results of the investigation show that the transport system responsible for the transfer of taurine is selectively impaired by the drug, whereas the other transport systems are either stimulated or not affected. The inhibitory effect of the drug on taurine transport appears to be due to interference with calmodulin-dependent processes because calmodulin antagonists such as W-7, calmidazolium, and CGS 9343B mimic the effects of cyclosporin A. FK506, another immunosuppressive drug that is currently undergoing clinical trials, does not have this inhibitory effect.

    Topics: Biological Transport, Active; Cell Line; Choriocarcinoma; Cyclosporine; Female; Humans; Placenta; Pregnancy; Tacrolimus; Taurine; Tumor Cells, Cultured; Uterine Neoplasms

1992