tacrolimus and Takayasu-Arteritis

We encountered the rare case of a 50-year-old woman who developed rheumatoid arthritis (RA) while suffering from Takayasu's arteritis of arch vessel type. prednisolone (PSL) therapy was continued at a maintenance dose of 7.5 mg due to recurring inflammation. She was affected with RA for 7 years after Takayasu's arteritis. Disease-modifying antirheumatic drugs (DMARDs) were unusable because of side effects. In the summer of 2005, RA activity increased, and treatment with tacrolimus hydrate at 1.5 mg was started; thereafter, the activity of RA and Takayasu's arteritis was relieved, especially MRA findings. We report that therapy with tacrolimus hydrate markedly relieved two disorders, and review the literature.

Topics: Angiography; Arthritis, Rheumatoid; Female; Humans; Immunosuppressive Agents; Middle Aged; Tacrolimus; Takayasu Arteritis

Topics: Adult; Carotid Stenosis; Cord Blood Stem Cell Transplantation; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Myelodysplastic Syndromes; Neutrophils; Tacrolimus; Takayasu Arteritis; Time Factors; Tomography, X-Ray Computed; Transplantation, Homologous; Treatment Outcome

Topics: Child; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Ribonucleosides; Tacrolimus; Takayasu Arteritis; Treatment Outcome

Topics: C-Reactive Protein; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Methotrexate; Prednisolone; Tacrolimus; Takayasu Arteritis; Young Adult