tacrolimus and Meningitis

tacrolimus has been researched along with Meningitis* in 2 studies

Reviews

1 review(s) available for tacrolimus and Meningitis

ArticleYear
Multifocal Fibrosclerosis with Hypertrophic Pachymeningitis and a Soft Tissue Mass around the Thoracic Vertebral Bodies: A Case Report with Review of the Literature.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:17

    Multifocal fibrosclerosis is the term used to represent a combination of similar fibrous lesions occurring at different anatomical sites. We herein report a hypertrophic pachymeningitis patient with a soft tissue mass around the thoracic vertebral bodies. A histopathological analysis of the biopsied tissues from both lesions showed dense fibrosis and a marked infiltration of lymphocytes and plasma cells, which lead to the diagnosis of multifocal fibrosclerosis. This pathological condition closely resembles that of IgG4-related disease and is a very rare combination of manifestations. Our case suggests that hypertrophic pachymeningitis patients need to also undergo a whole body examination.

    Topics: Aged; Anti-Inflammatory Agents; Humans; Hypertrophy; Immunosuppressive Agents; Male; Meningitis; Methylprednisolone; Plasma Cells; Retroperitoneal Fibrosis; Tacrolimus; Thoracic Vertebrae; Treatment Outcome

2015

Other Studies

1 other study(ies) available for tacrolimus and Meningitis

ArticleYear
[Orbital apex syndrome due to relapse during steroid tapering in a patient with MPO-ANCA-positive IgG4-related hypertrophic pachymeningitis].
    Rinsho shinkeigaku = Clinical neurology, 2014, Volume: 54, Issue:1

    A 75-year-old man developed hearing loss and hoarseness; 5 months later, he suffered from headache and loss of appetite. A blood test showed an inflammatory reaction, a high level of serum IgG4 (254.0 mg/dl), and positive reaction for MPO-ANCA. Gadolinium enhanced T1 weighted head magnetic resonance imaging (MRI) revealed dural thickening with marked enhancement. Infiltration of lymphocytes and anti-IgG4-positive plasma cells were detected in the dura mater by meningeal biopsy; thus, he was diagnosed with MPO-ANCA-positive IgG4-related hypertrophic pachymeningitis. His clinical manifestations, and serologic and MRI findings improved with steroid treatment; however, they recurred during steroid tapering and he presented with right orbital apex syndrome. We then added an immunosuppressive drug to his regimen. It was difficult to reduce the symptoms of this case, with oral steroid monotherapy, and its combination with an immunosuppressive drug was necessary.

    Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Humans; Hypertrophy; Immunoglobulin G; Immunosuppressive Agents; Male; Meningitis; Methylprednisolone; Orbital Diseases; Peroxidase; Recurrence; Tacrolimus

2014