tacrolimus and Hidradenitis-Suppurativa

Pyoderma gangrenosum is an inflammatory disease that has been found to be associated with many systemic illnesses. The case presented here is of a man with a 20-year history of hidradenitis suppurativa who developed pyoderma gangrenosum. The pyoderma lesions appeared as a single outbreak which resolved totally after immunosuppressive treatment. This association has been reported only rarely in the literature. Furthermore, in the cases reported, no relationship was apparent between the activity of both diseases. In all cases the clinical course appeared independent, with no apparent overlap in inflammatory activity or response to the drugs administered.

Topics: Abscess; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal; Cyclosporine; Drug Therapy, Combination; Hidradenitis Suppurativa; Humans; Immunosuppressive Agents; Infliximab; Male; Middle Aged; Pyoderma Gangrenosum; Retinoids; Skin Ulcer; Tacrolimus

Topics: Adalimumab; Hidradenitis Suppurativa; Humans; Ointments; Severity of Illness Index; Tacrolimus; Treatment Outcome

Topics: Administration, Topical; Axilla; Female; Hidradenitis Suppurativa; Humans; Immunosuppressive Agents; Tacrolimus; Young Adult

Topics: Cyclosporine; Drug Eruptions; Drug Substitution; Hidradenitis Suppurativa; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Remission, Spontaneous; Tacrolimus; Young Adult