tacrolimus and Cogan-Syndrome

The constellation of ocular symptoms known as Balint syndrome is a rare disorder seen in bilateral parieto-occipital lesions and is most frequently due to arterial occlusive disease or acute hypertension. Here we present the case of a patient with tacrolimus-induced posterior reversible encephalopathy syndrome (PRES) who presented with optic ataxia, simultanagnosia, and ocular apraxia. These ocular findings, consistent with Balint syndrome, are rarely the initial presentation of PRES. This case highlights the importance of early recognition of this unusual phenomenon, as well as the importance of an individualized rehabilitation plan to maximize functional independence in these patients.. V.

Topics: Adult; Apraxias; Cogan Syndrome; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Occipital Lobe; Parietal Lobe; Posterior Leukoencephalopathy Syndrome; Tacrolimus