tacrine has been researched along with Trypanosomiasis, African in 1 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human African Trypanosomiasis (HAT) is caused by two subspecies of the genus Trypanosoma, namely Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense." | 1.46 | Bistacrines as potential antitrypanosomal agents. ( Bruhn, H; Fuß, A; Göllner, S; Holzgrabe, U; Katzowitsch, E; Krauth-Siegel, RL; Kucharski, A; Miliu, A; Schirmeister, T; Schmidt, I; Stich, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, I | 1 |
| Göllner, S | 1 |
| Fuß, A | 1 |
| Stich, A | 1 |
| Kucharski, A | 1 |
| Schirmeister, T | 1 |
| Katzowitsch, E | 1 |
| Bruhn, H | 1 |
| Miliu, A | 1 |
| Krauth-Siegel, RL | 1 |
| Holzgrabe, U | 1 |
1 other study available for tacrine and Trypanosomiasis, African
| Article | Year |
|---|---|
Bistacrines as potential antitrypanosomal agents.
Topics: Animals; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Mice; Molecular Structure; | 2017 |