tacrine has been researched along with Organophosphate Poisoning in 3 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Organophosphate Poisoning: Poisoning due to exposure to ORGANOPHOSPHORUS COMPOUNDS, such as ORGANOPHOSPHATES; ORGANOTHIOPHOSPHATES; and ORGANOTHIOPHOSPHONATES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have assessed in vivo the mortality-reducing efficacy of a group of known AChE inhibitors, when given in equitoxic dosage before exposure to the OPC paraoxon." | 1.39 | Usefulness of administration of non-organophosphate cholinesterase inhibitors before acute exposure to organophosphates: assessment using paraoxon. ( Hasan, MY; Kuča, K; Lorke, DE; Nurulain, SM; Petroianu, GA; Shafiullah, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Petroianu, GA | 1 |
| Nurulain, SM | 1 |
| Shafiullah, M | 1 |
| Hasan, MY | 1 |
| Kuča, K | 1 |
| Lorke, DE | 1 |
| Bajgar, J | 1 |
| Patocka, J | 1 |
| Fusek, J | 1 |
| Hrdina, V | 1 |
| Freeman, SE | 1 |
| Dawson, RM | 1 |
1 review available for tacrine and Organophosphate Poisoning
| Article | Year |
|---|---|
Tacrine: a pharmacological review.
Topics: Alzheimer Disease; Animals; Antidotes; Cholinesterases; Drug Interactions; Hallucinogens; Humans; Io | 1991 |
2 other studies available for tacrine and Organophosphate Poisoning
| Article | Year |
|---|---|
Usefulness of administration of non-organophosphate cholinesterase inhibitors before acute exposure to organophosphates: assessment using paraoxon.
Topics: Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Lethal Dose 50; Male; Organoph | 2013 |
Some possibilities of protection against acetylcholinesterase inhibition by organophosphates in vivo.
Topics: Aminoacridines; Animals; Benactyzine; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Drug | 1984 |