tacrine has been researched along with Muscle Relaxation in 5 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate if tacrine induces reduction of calcium ions through chelation and/or inhibits directly calmodulin's participation in the contractile processes, thus causing smooth muscle relaxation which is not characteristic of a typical acetylcholinesterase blocker." | 3.73 | Effect of tacrine on cytosolic Ca2+ level and calmodulin in gastric muscle tissues of rat. ( Argirova, MD; Krastev, AD; Minkova, EI; Nikolov, RR; Prisadova, NA; Terzieva, D; Turiiski, VI, 2006) |
| "10(-5) mol/l caused smooth muscle contraction, which was blocked by atropine 1." | 3.72 | Influence of tacrine on dopamine-induced reactions of the gastric smooth muscle of rats. ( Getova-Spassova, D; Krustev, A; Spassov, V; Turijski, V, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, L | 1 |
| Appenroth, D | 1 |
| Decker, M | 1 |
| Kiehntopf, M | 1 |
| Roegler, C | 1 |
| Deufel, T | 1 |
| Fleck, C | 1 |
| Peng, S | 1 |
| Zhang, Y | 1 |
| Lehmann, J | 1 |
| Turijski, V | 1 |
| Krustev, A | 1 |
| Getova-Spassova, D | 1 |
| Spassov, V | 1 |
| Krustev, AD | 1 |
| Argirova, MD | 2 |
| Getova, DP | 1 |
| Turiiski, VI | 2 |
| Prissadova, NA | 1 |
| Prisadova, NA | 1 |
| Minkova, EI | 1 |
| Nikolov, RR | 1 |
| Terzieva, D | 1 |
| Krastev, AD | 1 |
| de los Ríos, C | 1 |
| Marco, JL | 1 |
| Carreiras, MD | 1 |
| Chinchón, PM | 1 |
| García, AG | 1 |
| Villarroya, M | 1 |
5 other studies available for tacrine and Muscle Relaxation
| Article | Year |
|---|---|
Synthesis and biological evaluation of NO-donor-tacrine hybrids as hepatoprotective anti-Alzheimer drug candidates.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; | 2008 |
Influence of tacrine on dopamine-induced reactions of the gastric smooth muscle of rats.
Topics: Animals; Atropine; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Dru | 2004 |
Calcium-independent tacrine-induced relaxation of rat gastric corpus smooth muscles.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Calcium Channel Blockers; Cholinergic Antagonists; Cholin | 2006 |
Effect of tacrine on cytosolic Ca2+ level and calmodulin in gastric muscle tissues of rat.
Topics: Animals; Calcium; Calmodulin; Chelating Agents; Cholinesterase Inhibitors; Cytosol; Dose-Response Re | 2006 |
Novel tacrine derivatives that block neuronal calcium channels.
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cattle; Chro | 2002 |