tacrine has been researched along with Learning Disabilities in 10 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil is a member of a new class of centrally acting cholinesterase inhibitors which preferentially inhibit acetylcholinesterase rather than butyrylcholinesterase." | 1.31 | Donepezil, a centrally acting acetylcholinesterase inhibitor, alleviates learning deficits in hypocholinergic models in rats. ( Kosasa, T; Kuriya, Y; Ogura, H; Yamanishi, Y, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, RW | 1 |
| Zhang, RS | 1 |
| Chang, M | 1 |
| Peng, YL | 1 |
| Wang, P | 1 |
| Hu, SQ | 1 |
| Choi, CL | 1 |
| Yin, M | 1 |
| Wang, R | 1 |
| Han, YF | 2 |
| Kim, DH | 1 |
| Yoon, BH | 1 |
| Kim, YW | 1 |
| Lee, S | 1 |
| Shin, BY | 1 |
| Jung, JW | 1 |
| Kim, HJ | 1 |
| Lee, YS | 1 |
| Choi, JS | 1 |
| Kim, SY | 1 |
| Lee, KT | 1 |
| Ryu, JH | 1 |
| Eguchi, J | 1 |
| Yuasa, T | 1 |
| Egawa, M | 1 |
| Tobe, A | 1 |
| Riekkinen, P | 1 |
| Ikonen, S | 1 |
| Aura, J | 1 |
| Riekkinen, M | 1 |
| Ogura, H | 1 |
| Kosasa, T | 1 |
| Kuriya, Y | 1 |
| Yamanishi, Y | 1 |
| Pan, SY | 1 |
| Ueki, A | 2 |
| Miyoshi, K | 2 |
| Mohammed, AK | 1 |
| Wahlström, G | 1 |
| Archer, T | 1 |
| Nordberg, A | 1 |
| Hagan, JJ | 1 |
| Jansen, JH | 1 |
| Nefkens, FE | 1 |
| de Boer, T | 1 |
10 other studies available for tacrine and Learning Disabilities
| Article | Year |
|---|---|
Reversal of scopolamine-induced spatial and recognition memory deficits in mice by novel multifunctional dimers bis-cognitins.
Topics: Analysis of Variance; Animals; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, A | 2012 |
The seed extract of Cassia obtusifolia ameliorates learning and memory impairments induced by scopolamine or transient cerebral hypoperfusion in mice.
Topics: Administration, Oral; Animals; Avoidance Learning; Behavior, Animal; Cassia; Cholinesterase Inhibito | 2007 |
Effects of a novel compound MCI-225 on impaired learning and memory in rats.
Topics: Animals; Avoidance Learning; Behavior, Animal; Carbon Dioxide; Cholinesterase Inhibitors; Learning D | 1994 |
Tetrahydroaminoacridine and D-cycloserine fail to alleviate the water maze spatial navigation defect induced by hippocampal inactivation.
Topics: Anesthetics, Local; Animals; Choline O-Acetyltransferase; Cycloserine; Drug Therapy, Combination; Es | 1999 |
Donepezil, a centrally acting acetylcholinesterase inhibitor, alleviates learning deficits in hypocholinergic models in rats.
Topics: Animals; Avoidance Learning; Basal Nucleus of Meynert; Cholinesterase Inhibitors; Donepezil; Dose-Re | 2000 |
Learning deficits induced by 4 belladonna alkaloids are preferentially attenuated by tacrine.
Topics: Animals; Atropine; Avoidance Learning; Cholinesterase Inhibitors; Learning Disabilities; Male; Mice; | 2000 |
Reversal of learning impairment in ventral globus pallidus-lesioned rats by combination of continuous intracerebroventricular choline infusion and oral cholinergic drug administration.
Topics: Acetylcholine; Administration, Oral; Aminoquinolines; Animals; Avoidance Learning; Brain Chemistry; | 1991 |
[Cholinesterase inhibitor].
Topics: Acetylcholine; Alzheimer Disease; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; | 1991 |
Learning deficits in aged rats pretreated chronically with barbital and tested late in abstinence: alleviation by tetrahydroaminoacridine.
Topics: Age Factors; Animals; Barbital; Brain; Learning; Learning Disabilities; Male; Organ Size; Physostigm | 1990 |
Therapeutic effect of THA on hemicholinium-3-induced learning impairment is independent of serotonergic and noradrenergic systems.
Topics: 5,7-Dihydroxytryptamine; Aminoacridines; Animals; Benzylamines; Desipramine; Discrimination, Psychol | 1990 |