tacrine has been researched along with Inflammation in 5 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we performed intravenous administrations of velnacrine (VLN) and acetylcholine (ACh), respectively, AChE inhibitor and substrate, in an animal model of lipopolysaccharide (LPS)-induced inflammation in Wistar rats." | 3.79 | Effects of acetylcholine on an animal mode of inflammation. ( Saldanha, C; Silva-Herdade, AS, 2013) |
| "Inflammation has been recently implicated in pathogenesis of dementia disorders." | 1.34 | Effect of anti-dementia drugs on LPS induced neuroinflammation in mice. ( Agrawal, R; Nath, C; Shukla, R; Tyagi, E, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, Y | 1 |
| Zhou, H | 1 |
| Gu, Q | 1 |
| Xu, J | 1 |
| AlFadly, ED | 1 |
| Elzahhar, PA | 1 |
| Tramarin, A | 1 |
| Elkazaz, S | 1 |
| Shaltout, H | 1 |
| Abu-Serie, MM | 1 |
| Janockova, J | 1 |
| Soukup, O | 1 |
| Ghareeb, DA | 1 |
| El-Yazbi, AF | 1 |
| Rafeh, RW | 1 |
| Bakkar, NZ | 1 |
| Kobeissy, F | 1 |
| Iriepa, I | 1 |
| Moraleda, I | 1 |
| Saudi, MNS | 1 |
| Bartolini, M | 1 |
| Belal, ASF | 1 |
| Silva-Herdade, AS | 1 |
| Saldanha, C | 1 |
| Tyagi, E | 1 |
| Agrawal, R | 1 |
| Nath, C | 1 |
| Shukla, R | 1 |
| Altman, J | 1 |
5 other studies available for tacrine and Inflammation
| Article | Year |
|---|---|
Synthesis and evaluation of tetrahydroisoquinoline-benzimidazole hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Benz | 2019 |
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
Topics: Acetylcholine; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Cyclooxygenase 2 In | 2019 |
Effects of acetylcholine on an animal mode of inflammation.
Topics: Acetylcholine; Animals; Cell Movement; Cholinesterase Inhibitors; Endothelium, Vascular; Inflammatio | 2013 |
Effect of anti-dementia drugs on LPS induced neuroinflammation in mice.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Brain; Cholinesterase Inhibitors; Dementia; Don | 2007 |
Developing therapies for Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Brain; Cholinesterase In | 1995 |