tacrine has been researched along with Glioma in 4 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tacrine treatment did not alter the level of HSP-70 in cell extracts and tacrine affected mildly the secretion of PN-1." | 1.29 | Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines. ( Farlow, MR; Lahiri, DK; Lewis, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, BF | 1 |
| Peng, FF | 1 |
| Zhang, JZ | 1 |
| Wu, DC | 1 |
| Lahiri, DK | 1 |
| Lewis, S | 1 |
| Farlow, MR | 1 |
| De Ferrari, GV | 1 |
| von Bernhardi, R | 1 |
| Calderón, FH | 1 |
| Luza, SC | 1 |
| Inestrosa, NC | 1 |
| Robbins, J | 1 |
| Sim, JA | 1 |
4 other studies available for tacrine and Glioma
| Article | Year |
|---|---|
[Protective effects of tacrine and donepezil against staurosporine-induced apoptotic death].
Topics: Animals; Apoptosis; Cholinesterase Inhibitors; Donepezil; Glioma; HeLa Cells; Humans; Hybrid Cells; | 2002 |
Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines.
Topics: Amyloid beta-Protein Precursor; Animals; Cell Differentiation; Cell Line; Cholinesterase Inhibitors; | 1994 |
Responses induced by tacrine in neuronal and non-neuronal cell lines.
Topics: Animals; Cell Differentiation; Cell Size; Dose-Response Relationship, Drug; Glioma; Mice; Neuroblast | 1998 |
A transient outward current in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 4-Aminopyridine; Action Potentials; Adrenergic Fibers; Animals; Barium; Calcium; Elapid Venoms; Glio | 1990 |