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tacrine and Glioma

tacrine has been researched along with Glioma in 4 studies

Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Tacrine treatment did not alter the level of HSP-70 in cell extracts and tacrine affected mildly the secretion of PN-1."1.29Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines. ( Farlow, MR; Lahiri, DK; Lewis, S, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, BF1
Peng, FF1
Zhang, JZ1
Wu, DC1
Lahiri, DK1
Lewis, S1
Farlow, MR1
De Ferrari, GV1
von Bernhardi, R1
Calderón, FH1
Luza, SC1
Inestrosa, NC1
Robbins, J1
Sim, JA1

Other Studies

4 other studies available for tacrine and Glioma

ArticleYear
[Protective effects of tacrine and donepezil against staurosporine-induced apoptotic death].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:2

    Topics: Animals; Apoptosis; Cholinesterase Inhibitors; Donepezil; Glioma; HeLa Cells; Humans; Hybrid Cells;

2002
Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines.
    Journal of neuroscience research, 1994, Apr-15, Volume: 37, Issue:6

    Topics: Amyloid beta-Protein Precursor; Animals; Cell Differentiation; Cell Line; Cholinesterase Inhibitors;

1994
Responses induced by tacrine in neuronal and non-neuronal cell lines.
    Journal of neuroscience research, 1998, May-15, Volume: 52, Issue:4

    Topics: Animals; Cell Differentiation; Cell Size; Dose-Response Relationship, Drug; Glioma; Mice; Neuroblast

1998
A transient outward current in NG108-15 neuroblastoma x glioma hybrid cells.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:1-2

    Topics: 4-Aminopyridine; Action Potentials; Adrenergic Fibers; Animals; Barium; Calcium; Elapid Venoms; Glio

1990