tacrine has been researched along with Glial Cell Tumors in 4 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tacrine treatment did not alter the level of HSP-70 in cell extracts and tacrine affected mildly the secretion of PN-1." | 1.29 | Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines. ( Farlow, MR; Lahiri, DK; Lewis, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, BF | 1 |
| Peng, FF | 1 |
| Zhang, JZ | 1 |
| Wu, DC | 1 |
| Lahiri, DK | 1 |
| Lewis, S | 1 |
| Farlow, MR | 1 |
| De Ferrari, GV | 1 |
| von Bernhardi, R | 1 |
| Calderón, FH | 1 |
| Luza, SC | 1 |
| Inestrosa, NC | 1 |
| Robbins, J | 1 |
| Sim, JA | 1 |
4 other studies available for tacrine and Glial Cell Tumors
| Article | Year |
|---|---|
[Protective effects of tacrine and donepezil against staurosporine-induced apoptotic death].
Topics: Animals; Apoptosis; Cholinesterase Inhibitors; Donepezil; Glioma; HeLa Cells; Humans; Hybrid Cells; | 2002 |
Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines.
Topics: Amyloid beta-Protein Precursor; Animals; Cell Differentiation; Cell Line; Cholinesterase Inhibitors; | 1994 |
Responses induced by tacrine in neuronal and non-neuronal cell lines.
Topics: Animals; Cell Differentiation; Cell Size; Dose-Response Relationship, Drug; Glioma; Mice; Neuroblast | 1998 |
A transient outward current in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 4-Aminopyridine; Action Potentials; Adrenergic Fibers; Animals; Barium; Calcium; Elapid Venoms; Glio | 1990 |