tacrine has been researched along with Dyskinesia, Drug-Induced in 9 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Intact male GPR88 KO mice showed diminished tacrine-induced PD-like tremor and spontaneous hyperlocomotion." | 3.96 | Genetic deletion of GPR88 enhances the locomotor response to L-DOPA in experimental parkinsonism while counteracting the induction of dyskinesia. ( Mannoury-la-Cour, C; Mantas, I; Millan, MJ; Svenningsson, P; Yang, Y; Zhang, X, 2020) |
| "Tacrine-treated rats showed a slight increase in the average initiation time for fast responses (i." | 1.30 | Motor dysfunction produced by tacrine administration in rats. ( Aberman, J; Carriero, DL; Gianutsos, G; Mayorga, AJ; Outslay, G; Salamone, JD, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Mantas, I | 1 |
| Yang, Y | 1 |
| Mannoury-la-Cour, C | 1 |
| Millan, MJ | 1 |
| Zhang, X | 1 |
| Svenningsson, P | 1 |
| Hanus, H | 5 |
| Tůtma, I | 1 |
| Zapletálek, M | 3 |
| Fusek, J | 5 |
| Hrdina, V | 3 |
| Ingram, NA | 1 |
| Newgreen, DB | 1 |
| Tůma, I | 2 |
| Patocka, J | 2 |
| Carriero, DL | 1 |
| Outslay, G | 1 |
| Mayorga, AJ | 1 |
| Aberman, J | 1 |
| Gianutsos, G | 1 |
| Salamone, JD | 2 |
| Cousins, MS | 1 |
| Atherton, A | 1 |
2 trials available for tacrine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
The use of tacrine for tardive dyskinesia.
Topics: Administration, Oral; Adult; Aminoacridines; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle | 1983 |
[Treatment of tardive dyskinesias with 7-methoxycrine. II].
Topics: Adult; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Tacrine | 1993 |
7 other studies available for tacrine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Genetic deletion of GPR88 enhances the locomotor response to L-DOPA in experimental parkinsonism while counteracting the induction of dyskinesia.
Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Cholinesterase Inhibitors; Corpus Striatum; Dopami | 2020 |
Treatment of tardive dyskinesia by single and repeated application of 7-methoxytacrin.
Topics: Adult; Anti-Dyskinesia Agents; Antipsychotic Agents; Chronic Disease; Dyskinesia, Drug-Induced; Euph | 1991 |
[Treatment of tardive dyskinesias with 7-methoxytacrine. I].
Topics: Adult; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Tacrine | 1993 |
Motor dysfunction produced by tacrine administration in rats.
Topics: Animals; Cholinesterase Inhibitors; Conditioning, Operant; Dose-Response Relationship, Drug; Dyskine | 1997 |
Behavioral and electromyographic characterization of the local frequency of tacrine-induced tremulous jaw movements.
Topics: Animals; Behavior, Animal; Cholinesterase Inhibitors; Dyskinesia, Drug-Induced; Electrodes, Implante | 1998 |
First experience with the application of 7-methoxytacrine to psychiatric patients.
Topics: Adult; Aminoacridines; Antipsychotic Agents; Cholinesterase Inhibitors; Dyskinesia, Drug-Induced; Fe | 1989 |
[Initial experience with the administration of 7-methoxyacrine to patients with psychological disorders].
Topics: Adult; Aminoacridines; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Tacrine | 1989 |