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tacrine and Bradycardia

tacrine has been researched along with Bradycardia in 3 studies

Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.

Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Research Excerpts

ExcerptRelevanceReference
" TC and TCCP rats exhibited a decreased response to: 1) phenylephrine-induced vagal baroreflex bradycardia; 2) methoctramine-, 4-DAMP- and tropicamide-induced tachycardia; 3) methoctramine-induced QRS shortening, and 4) tropicamide-induced QT prolongation."3.74The cholinergic system in cyclophosphamide-induced Chagas dilated myocardiopathy in Trypanosoma-cruzi-infected rats: an electrocardiographic study. ( Bonfante-Cabarcas, R; Labrador-Hernández, M; Rodríguez-Bonfante, C; Romero-Contreras, U; Rumenoff, L; Suárez-Graterol, O, 2008)
" The serum half-life was 1."1.28Pharmacokinetics of tacrine hydrochloride in Alzheimer's disease. ( Ford, JM; Forsyth, DR; Morgan, RA; Roberts, CJ; Truman, CA; Wilcock, GK, 1989)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Labrador-Hernández, M1
Suárez-Graterol, O1
Romero-Contreras, U1
Rumenoff, L1
Rodríguez-Bonfante, C1
Bonfante-Cabarcas, R1
Allal, C1
Lazartigues, E1
Tran, MA1
Brefel-Courbon, C1
Gharib, C1
Montastruc, JL1
Rascol, O1
Forsyth, DR1
Wilcock, GK1
Morgan, RA1
Truman, CA1
Ford, JM1
Roberts, CJ1

Other Studies

3 other studies available for tacrine and Bradycardia

ArticleYear
The cholinergic system in cyclophosphamide-induced Chagas dilated myocardiopathy in Trypanosoma-cruzi-infected rats: an electrocardiographic study.
    Investigacion clinica, 2008, Volume: 49, Issue:2

    Topics: Acetylcholine; Animals; Autoimmune Diseases of the Nervous System; Baroreflex; Bradycardia; CD8-Posi

2008
Central cardiovascular effects of tacrine in the conscious dog: a role for catecholamines and vasopressin release.
    European journal of pharmacology, 1998, May-08, Volume: 348, Issue:2-3

    Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cholinesterase Inhibitors; Dogs; Dose-Response Relat

1998
Pharmacokinetics of tacrine hydrochloride in Alzheimer's disease.
    Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:6

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Aminoacridines; Biological Availab

1989