tacrine has been researched along with Bradycardia in 3 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
Excerpt | Relevance | Reference |
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" TC and TCCP rats exhibited a decreased response to: 1) phenylephrine-induced vagal baroreflex bradycardia; 2) methoctramine-, 4-DAMP- and tropicamide-induced tachycardia; 3) methoctramine-induced QRS shortening, and 4) tropicamide-induced QT prolongation." | 3.74 | The cholinergic system in cyclophosphamide-induced Chagas dilated myocardiopathy in Trypanosoma-cruzi-infected rats: an electrocardiographic study. ( Bonfante-Cabarcas, R; Labrador-Hernández, M; Rodríguez-Bonfante, C; Romero-Contreras, U; Rumenoff, L; Suárez-Graterol, O, 2008) |
" The serum half-life was 1." | 1.28 | Pharmacokinetics of tacrine hydrochloride in Alzheimer's disease. ( Ford, JM; Forsyth, DR; Morgan, RA; Roberts, CJ; Truman, CA; Wilcock, GK, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Labrador-Hernández, M | 1 |
Suárez-Graterol, O | 1 |
Romero-Contreras, U | 1 |
Rumenoff, L | 1 |
Rodríguez-Bonfante, C | 1 |
Bonfante-Cabarcas, R | 1 |
Allal, C | 1 |
Lazartigues, E | 1 |
Tran, MA | 1 |
Brefel-Courbon, C | 1 |
Gharib, C | 1 |
Montastruc, JL | 1 |
Rascol, O | 1 |
Forsyth, DR | 1 |
Wilcock, GK | 1 |
Morgan, RA | 1 |
Truman, CA | 1 |
Ford, JM | 1 |
Roberts, CJ | 1 |
3 other studies available for tacrine and Bradycardia
Article | Year |
---|---|
The cholinergic system in cyclophosphamide-induced Chagas dilated myocardiopathy in Trypanosoma-cruzi-infected rats: an electrocardiographic study.
Topics: Acetylcholine; Animals; Autoimmune Diseases of the Nervous System; Baroreflex; Bradycardia; CD8-Posi | 2008 |
Central cardiovascular effects of tacrine in the conscious dog: a role for catecholamines and vasopressin release.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cholinesterase Inhibitors; Dogs; Dose-Response Relat | 1998 |
Pharmacokinetics of tacrine hydrochloride in Alzheimer's disease.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Aminoacridines; Biological Availab | 1989 |