tacrine has been researched along with Bradyarrhythmia in 3 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " TC and TCCP rats exhibited a decreased response to: 1) phenylephrine-induced vagal baroreflex bradycardia; 2) methoctramine-, 4-DAMP- and tropicamide-induced tachycardia; 3) methoctramine-induced QRS shortening, and 4) tropicamide-induced QT prolongation." | 3.74 | The cholinergic system in cyclophosphamide-induced Chagas dilated myocardiopathy in Trypanosoma-cruzi-infected rats: an electrocardiographic study. ( Bonfante-Cabarcas, R; Labrador-Hernández, M; Rodríguez-Bonfante, C; Romero-Contreras, U; Rumenoff, L; Suárez-Graterol, O, 2008) |
| " The serum half-life was 1." | 1.28 | Pharmacokinetics of tacrine hydrochloride in Alzheimer's disease. ( Ford, JM; Forsyth, DR; Morgan, RA; Roberts, CJ; Truman, CA; Wilcock, GK, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Labrador-Hernández, M | 1 |
| Suárez-Graterol, O | 1 |
| Romero-Contreras, U | 1 |
| Rumenoff, L | 1 |
| Rodríguez-Bonfante, C | 1 |
| Bonfante-Cabarcas, R | 1 |
| Allal, C | 1 |
| Lazartigues, E | 1 |
| Tran, MA | 1 |
| Brefel-Courbon, C | 1 |
| Gharib, C | 1 |
| Montastruc, JL | 1 |
| Rascol, O | 1 |
| Forsyth, DR | 1 |
| Wilcock, GK | 1 |
| Morgan, RA | 1 |
| Truman, CA | 1 |
| Ford, JM | 1 |
| Roberts, CJ | 1 |
3 other studies available for tacrine and Bradyarrhythmia
| Article | Year |
|---|---|
The cholinergic system in cyclophosphamide-induced Chagas dilated myocardiopathy in Trypanosoma-cruzi-infected rats: an electrocardiographic study.
Topics: Acetylcholine; Animals; Autoimmune Diseases of the Nervous System; Baroreflex; Bradycardia; CD8-Posi | 2008 |
Central cardiovascular effects of tacrine in the conscious dog: a role for catecholamines and vasopressin release.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cholinesterase Inhibitors; Dogs; Dose-Response Relat | 1998 |
Pharmacokinetics of tacrine hydrochloride in Alzheimer's disease.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Aminoacridines; Biological Availab | 1989 |