tacrine has been researched along with Acute Hepatic Failure in 1 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Approximately half the patients treated with tacrine have liver enzyme abnormalities develop, primarily in the first 12 weeks of therapy, that resolve with discontinuation of drug or dosage adjustment." | 1.30 | Tacrine. A cause of fatal hepatotoxicity? ( Blackard, WG; Crowe, DR; Fallon, MB; Sood, GK, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blackard, WG | 1 |
| Sood, GK | 1 |
| Crowe, DR | 1 |
| Fallon, MB | 1 |
1 other study available for tacrine and Acute Hepatic Failure
| Article | Year |
|---|---|
Tacrine. A cause of fatal hepatotoxicity?
Topics: Aged; Alzheimer Disease; Fatal Outcome; Female; Humans; Liver Failure, Acute; Liver Function Tests; | 1998 |