tacrine has been researched along with Acute Disease in 2 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "4) Velnacrine was shown to bind to both albumin and alpha 1-acid glycoprotein, but together they did not account for total binding." | 2.68 | Variability in the plasma protein binding of velnacrine (1-hydroxy tacrine hydrochloride). A potential agent for Alzheimer's disease. ( Ford, JM; Roberts, CJ; Wood, DM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wood, DM | 1 |
| Ford, JM | 1 |
| Roberts, CJ | 1 |
| Hammel, P | 1 |
| Larrey, D | 1 |
| Bernuau, J | 1 |
| Kalafat, M | 1 |
| Fréneaux, E | 1 |
| Babany, G | 1 |
| Degott, C | 1 |
| Feldmann, G | 1 |
| Pessayre, D | 1 |
| Benhamou, JP | 1 |
1 trial available for tacrine and Acute Disease
| Article | Year |
|---|---|
Variability in the plasma protein binding of velnacrine (1-hydroxy tacrine hydrochloride). A potential agent for Alzheimer's disease.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Binding, Compet | 1996 |
1 other study available for tacrine and Acute Disease
| Article | Year |
|---|---|
Acute hepatitis after tetrahydroaminoacridine administration for Alzheimer's disease.
Topics: Acute Disease; Aged; Alzheimer Disease; Aminoacridines; Chemical and Drug Induced Liver Injury; Fema | 1990 |