Page last updated: 2024-08-17

tabun and Organophosphate Poisoning

tabun has been researched along with Organophosphate Poisoning in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (13.51)	18.7374
1990's	11 (14.86)	18.2507
2000's	29 (39.19)	29.6817
2010's	22 (29.73)	24.3611
2020's	2 (2.70)	2.80

Authors

Authors	Studies
Kalisiak, J; Kovarik, Z; Maček Hrvat, N; Radić, Z; Sharpless, KB; Šinko, G; Taylor, P	1
Bird, M; Green, AC; Kassa, J; Tattersall, JEH; Timperley, CM	1
Caisberger, F; Hatlapatkova, J; Kassa, J; Misik, J; Pejchal, J; Sepsova, V; Zdarova Karasova, J	1
Bird, M; Green, AC; Kassa, J; Tattersall, JEH; Timperley, CM; Williams, RL	1
Box, K; Ceckova, M; Dolezal, R; Gorecki, L; Hepnarova, V; Hrabinova, M; Jankockova, J; Jost, P; Jun, D; Kobrlova, T; Korabecny, J; Kuca, K; Malinak, D; Musilek, K; Nepovimova, E; Nguyen, TD; Outhwaite, B; Pavek, P; Pham, NL; Psotka, M; Sorf, A; Soukup, O	1
Gorecki, L; Jun, D; Korabecny, J; Kuca, K; Kucera, T; Malinak, D; Musilek, K; Soukup, O	1
Thiermann, H; Von Der Wellen, J; Wille, T; Worek, F	1
Kopjar, N; Kuca, K; Lucić Vrdoljak, A; Musilek, K; Zeljezić, D; Zunec, S	1
Aas, P; Enger, S; Mariussen, E; Myhrer, T	1
Płusa, T; Sokołowski, R	1
Katalinić, M; Kovarik, Z; Maček Hrvat, N; Misik, J; Žďárová Karasová, J	1
Hatlapatková, J; Kassa, J; Žďárová Karasová, J	1
Cadieux, CL; Cerasoli, D; Koenig, JA; Koh, J; McDonough, J; Shih, TM; Wang, H; Zhang, Y	1
Berend, S; Kuca, K; Radić, B; Vrdoljak, AL	1
Bajgar, J; Jun, D; Karasova, J; Kassa, J; Kuca, K	1
Jung, YS; Karasova, J; Kassa, J; Kuca, K; Musilek, K	1
Berend, S; Katalinić, M; Kovarik, Z; Kuc, K; Musilek, K; Radić, B; Vrdoljak, AL	1
Jung, AY; Karasova, JZ; Kassa, J; Kuca, K; Musilek, K	1
Bajgar, J; Caisberger, F; Karasova, JZ; Kassa, J; Misik, J; Pavlikova, R	1
Berend, S; Kuca, K; Lucić Vrdoljak, A; Radić, B	1
Bajgar, J; Blaha, V; Cabal, J; Fusek, J; Karasova, JZ; Kassa, J; Tesarova, S	1
Berend, S; Katalinić, M; Kovarik, Z; Kuca, K; Radić, B; Vrdoljak, AL	1
Karasová, JZ; Kassa, J; Kuca, K; Musílek, K; Tesarová, S	1
Hamilton, MG; Lundy, PM; Mikler, J; Sawyer, TW	1
Bird, M; Chad, JE; Green, AC; Price, M; Tattersall, JE; Timperley, CM; Turner, SR	1
Berend, S; Katalinić, M; Kopjar, N; Kovarik, Z; Lovrić, J; Lucić Vrdoljak, A; Mesić, M; Radić, B; Rast, S; Želježić, D	1
Bajgar, J; Capek, L; Fusek, J; Hajek, P; Karasova, JZ; Kassa, J; Krs, O; Slizova, D; Voicu, VA	1
Jung, YS; Karasova, JZ; Kassa, J; Kuca, K; Musilek, K; Tesarova, S	1
Babu, UM; Condon, P; Mendez, A; Sambursky, R; VanDine, R	1
Kassa, J; Vachek, J	1
Kassa, J	4
Klein, R; Leikin, JB; Meislin, HW; Thomas, RG; Walter, FG	1
Bueters, TJ; Danhof, M; Groen, B; IJzerman, AP; Van Helden, HP	1
Kassa, J; Krejèová, G	1
DAHLBOM, R; DIAMANT, H; EDLUND, T; EKSTRAND, T; HOLMSTEDT, B	1
BROWN, RV; KUNKEL, AM; SOMERS, LM; WILLS, JH	1
CRAIG, FN	1
HEILBRONN, E; SUNDWALL, A	1
Sevelová, L; Vachek, J	1
Newmark, J	2
Kassa, J; Krejcová, G	1
Bajgar, J; Hájek, P; Krs, O; Slízová, D	1
Calić, M; Jelić, D; Jun, D; Kovarik, Z; Kuca, K; Radić, B; Vrdoljak, AL	1
Kellar, KJ	1
Cabal, J; Kassa, J; Kuca, K; Paar, M	1
Kassa, J; Kunesová, G	1
Berend, S; Calić, M; Jun, D; Kovarik, Z; Kuca, K; Lucić Vrdoljak, A; Radić, B	1
Jun, D; Kassa, J; Kuca, K	1
Karasova, J; Kassa, J	1
Karasova, J; Kassa, J; Kuca, K; Musilek, K	1
Humlicek, V; Kassa, J	1
Hrobak, PK	1
Berend, S; Bosak, A; Calić, M; Kovarik, Z; Radić, B; Sinko, G; Vrdoljak, AL	1
Bosković, B; Cetković, S; Cosić, M; Cvetković, M; Jandrić, D	1
Bosković, B; Jovanović, D; Kovacević, V	1
Clement, JG; Filbert, M	1
Kleine, A; Szinicz, L; Worek, F	1
Kirchner, T; Szinicz, L; Worek, F	1
Koplovitz, I; Stewart, JR	1
Bruijnzeel, PL; Busker, RW; Melchers, BP; van Helden, HP	1
Belkin, M; Solberg, Y	1
Holstege, CP; Kirk, M; Sidell, FR	1
Boulet, CA; Clement, JG; Hansen, AS	1
Anderson, DR; Harris, LW; Koplovitz, I; Lennox, WJ; Stewart, JR	1
Hagelsten, JO	1
Baraka, A	1
Hamilton, MG; Lundy, PM	1
Clement, JG; Gennings, C; Shiloff, JD	1
Pantelić, D	1

Reviews

8 review(s) available for tabun and Organophosphate Poisoning

Article	Year
[Today's threat of use of organophosphorus compounds]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2015, Volume: 39, Issue:231 Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Environmental Exposure; Humans; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Seizures; Soman	2015
Comparative protective effects of HI-6 and MMB-4 against organophosphorous nerve agent poisoning. Toxicology, 2011, Jul-29, Volume: 285, Issue:3 Topics: Antidotes; Chemical Warfare Agents; Humans; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman	2011
A review of nerve agent exposure for the critical care physician. Critical care medicine, 2002, Volume: 30, Issue:10 Topics: Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Humans; Nervous System; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Sarin; Soman	2002
Therapy for nerve agent poisoning. Archives of neurology, 2004, Volume: 61, Issue:5 Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman	2004
Pharmacological effects of oximes: how relevant are they? Archives of toxicology, 1996, Volume: 70, Issue:12 Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Organophosphate Poisoning; Organophosphates; Oximes; Poisoning; Pyridinium Compounds; Receptors, Cholinergic; Respiration; Soman; Synaptic Transmission	1996
The role of excitotoxicity in organophosphorous nerve agents central poisoning. Trends in pharmacological sciences, 1997, Volume: 18, Issue:6 Topics: Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Excitatory Amino Acid Antagonists; Humans; Neurons; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Sarin; Seizures; Soman; Synaptic Transmission	1997
Chemical warfare. Nerve agent poisoning. Critical care clinics, 1997, Volume: 13, Issue:4 Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Disaster Planning; Emergency Medical Services; Humans; Nervous System Diseases; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Sarin; Soman	1997
Chemical warfare--the nerve gases. Middle East journal of anaesthesiology, 1991, Volume: 11, Issue:1 Topics: Antidotes; Chemical Warfare Agents; Gas Poisoning; Humans; Organophosphate Poisoning; Organophosphates; Protective Clothing; Sarin; Soman	1991

Other Studies

66 other study(ies) available for tabun and Organophosphate Poisoning

Article	Year
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases. Toxicology letters, 2020, Mar-15, Volume: 321 Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; GPI-Linked Proteins; Humans; Kinetics; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Protein Conformation; Sarin; Structure-Activity Relationship	2020
Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment. Toxicology mechanisms and methods, 2020, Volume: 30, Issue:9 Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Reactivators; Lethal Dose 50; Male; Mice; Nicotinic Antagonists; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman; Time Factors	2020
The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats-A Comparison with Trimedoxime and the Oxime K203. Molecules (Basel, Switzerland), 2017, Jul-11, Volume: 22, Issue:7 Topics: Acetylcholinesterase; Animals; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Reactivators; Humans; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats, Wistar; Trimedoxime	2017
Evaluation of the Influence of Three Newly Developed Bispyridinium Anti-nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice. Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:4 Topics: Animals; Antidotes; Atropine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Humans; Lethal Dose 50; Male; Mice; Nerve Agents; Nicotinic Agonists; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Soman; Treatment Outcome	2018
In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley? Medicinal chemistry (Shariqah (United Arab Emirates)), 2018, Volume: 14, Issue:3 Topics: Animals; Antidotes; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Computer Simulation; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Paraoxon; Rats; Sarin	2018
Oxime K203: a drug candidate for the treatment of tabun intoxication. Archives of toxicology, 2019, Volume: 93, Issue:3 Topics: Acetylcholinesterase; Antidotes; Molecular Docking Simulation; Nerve Agents; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Trimedoxime	2019
Investigations of kinetic interactions between lipid emulsions, hydroxyethyl starch or dextran and organophosphorus compounds. Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:10 Topics: Biodegradation, Environmental; Chemical Warfare Agents; Cholinesterase Inhibitors; Dextrans; Emulsions; Erythrocytes; Half-Life; Humans; Hydroxyethyl Starch Derivatives; Kinetics; Malathion; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Pesticides	2013
In vivo evaluation of cholinesterase activity, oxidative stress markers, cyto- and genotoxicity of K048 oxime–a promising antidote against organophosphate poisoning. Basic & clinical pharmacology & toxicology, 2014, Volume: 114, Issue:4 Topics: Acetylcholinesterase; Animals; Antidotes; Cell Survival; Cholinesterase Inhibitors; Comet Assay; DNA Damage; Lethal Dose 50; Lipid Peroxidation; Lymphocytes; Male; Organophosphate Poisoning; Organophosphates; Oxidative Stress; Oximes; Phosphorylation; Pyridinium Compounds; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Toxicity Tests, Acute	2014
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats. Neurotoxicology, 2015, Volume: 50 Topics: Animals; Anticonvulsants; Antidotes; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Lethal Dose 50; Levetiracetam; Male; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Piracetam; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman	2015
Translation of in vitro to in vivo pyridinium oxime potential in tabun poisoning. Arhiv za higijenu rada i toksikologiju, 2015, Volume: 66, Issue:4 Topics: Adult; Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar	2015
The Evaluation of the Potency of Newly Developed Oximes (K727, K733) and Trimedoxime to Counteract Acute Neurotoxic Effects of Tabun in Rats. Acta medica (Hradec Kralove), 2015, Volume: 58, Issue:4 Topics: Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Muscarinic Antagonists; Nervous System; Neuroprotective Agents; Neurotoxicity Syndromes; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime	2015
Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents. Chemico-biological interactions, 2016, Nov-25, Volume: 259, Issue:Pt B Topics: Acetylcholinesterase; Animals; Cholinesterase Reactivators; Erythrocytes; Guinea Pigs; Half-Life; Humans; Kinetics; Male; Nerve Agents; Organophosphate Poisoning; Organophosphates; Oximes; Phenols; Pralidoxime Compounds; Recombinant Proteins; Sarin; Soman; Structure-Activity Relationship	2016
New bispyridinium oximes: in vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning. Chemico-biological interactions, 2008, Sep-25, Volume: 175, Issue:1-3 Topics: Animals; Chemical Warfare Agents; Enzyme Reactivators; Humans; In Vitro Techniques; Lethal Dose 50; Male; Mice; Mice, Inbred BALB C; Organophosphate Poisoning; Organophosphates; Oximes; Poisoning; Pyridinium Compounds; Soman	2008
A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats. Chemico-biological interactions, 2008, Sep-25, Volume: 175, Issue:1-3 Topics: Acetylcholinesterase; Animals; Chemical Warfare Agents; Enzyme Reactivators; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Rats; Rats, Wistar; Soman	2008
A comparison of the therapeutic and reactivating efficacy of newly developed oximes (K117, K127) and currently available oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice. Drug and chemical toxicology, 2008, Volume: 31, Issue:3 Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Cholinesterase Inhibitors; Diaphragm; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime	2008
Evaluation of oxime k203 as antidote in tabun poisoning. Arhiv za higijenu rada i toksikologiju, 2009, Volume: 60, Issue:1 Topics: Acetylcholinesterase; Animals; Antidotes; Butyrylcholinesterase; Chemical Warfare Agents; Enzyme Activation; Lethal Dose 50; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Rats; Trimedoxime	2009
A comparison of the neuroprotective efficacy of newly developed oximes (K117, K127) and currently available oxime (obidoxime) in tabun-poisoned rats. Toxicology mechanisms and methods, 2009, Volume: 19, Issue:3 Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Male; Motor Activity; Neuroprotective Agents; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar	2009
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of tabun poisoning in rats and mice. Journal of applied toxicology : JAT, 2010, Volume: 30, Issue:2 Topics: Acetylcholinesterase; Animals; Antidotes; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar	2010
The antidotal efficacy of the bispyridinium oximes K027 and TMB-4 against tabun poisoning in mice. Chemico-biological interactions, 2010, Sep-06, Volume: 187, Issue:1-3 Topics: Acetylcholinesterase; Animals; Antidotes; Catalytic Domain; Cholinesterase Inhibitors; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Phosphorylation; Pyridinium Compounds; Trimedoxime	2010
Tabun-inhibited rat tissue and blood cholinesterases and their reactivation with the combination of trimedoxime and HI-6 in vivo. Chemico-biological interactions, 2010, Sep-06, Volume: 187, Issue:1-3 Topics: Acetylcholinesterase; Animals; Central Nervous System; Cholinesterase Reactivators; Drug Therapy, Combination; Enzyme Activation; Female; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime	2010
In vivo experimental approach to treatment against tabun poisoning. Journal of enzyme inhibition and medicinal chemistry, 2010, Volume: 25, Issue:4 Topics: Animals; Atropine; Butanes; Chemical Warfare Agents; Cholinesterase Inhibitors; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Protective Agents; Pyridinium Compounds; Survival Rate; Treatment Outcome; Trimedoxime	2010
A comparison of the potency of newly developed oximes (K347, K628) and currently available oximes (obidoxime, HI-6) to counteract acute neurotoxic effects of Tabun in rats. Acta medica (Hradec Kralove), 2010, Volume: 53, Issue:2 Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Organophosphate Poisoning; Organophosphates; Oximes; Rats; Rats, Wistar	2010
Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist. Toxicology letters, 2011, Sep-25, Volume: 206, Issue:1 Topics: Animals; Cell Line, Tumor; Chemical Warfare Agents; Diaphragm; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ion Channel Gating; Male; Muscle Contraction; Nicotinic Antagonists; Organophosphate Poisoning; Organophosphates; Poisoning; Pyridinium Compounds; Sarin; Soman	2011
A conjugate of pyridine-4-aldoxime and atropine as a potential antidote against organophosphorus compounds poisoning. Acta biochimica Polonica, 2011, Volume: 58, Issue:2 Topics: Acetylcholinesterase; Adult; Animals; Antidotes; Atropine Derivatives; Cell Death; Cell Survival; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Assays; Erythrocytes; Humans; Lymphocytes; Male; Mice; Organophosphate Poisoning; Organophosphates; Paraoxon; Pralidoxime Compounds; Soman	2011
Combined approach to demonstrate acetylcholinesterase activity changes in the rat brain following tabun intoxication and its treatment. Toxicology mechanisms and methods, 2012, Volume: 22, Issue:1 Topics: Animals; Brain; Brain Mapping; Chemical Warfare Agents; Cholinesterase Reactivators; Cholinesterases; Female; Molecular Structure; Neurotoxicity Syndromes; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar	2012
A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in Tabun-poisoned rats. Basic & clinical pharmacology & toxicology, 2010, Volume: 107, Issue:5 Topics: Acute Disease; Animals; Autonomic Nervous System; Behavior, Animal; Chemical Warfare Agents; Hyperkinesis; Male; Molecular Structure; Muscle Tonus; Neuroprotective Agents; Neurotoxicity Syndromes; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Treatment Outcome	2010
A 10-minute point-of-care assay for detection of blood protein adducts resulting from low level exposure to organophosphate nerve agents. Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1 Topics: Adult; Blood Chemical Analysis; Blood Proteins; Chemical Warfare Agents; Cholinesterase Inhibitors; Cross Reactions; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Point-of-Care Systems; Sarin; Soman	2013
A comparison of the efficacy of pyridostigmine alone and the combination of pyridostigmine with anticholinergic drugs as pharmacological pretreatment of tabun-poisoned rats and mice. Toxicology, 2002, Aug-15, Volume: 177, Issue:2-3 Topics: Animals; Atropine; Cholinesterase Inhibitors; Drug Therapy, Combination; Female; Lethal Dose 50; Male; Mice; Organophosphate Poisoning; Organophosphates; Parasympatholytics; Pyridostigmine Bromide; Rats; Rats, Wistar	2002
The influence of anticholinergic drug and oxime selection on the effectiveness of antidotal treatment against tabun-induced poisoning in mice. Acta medica (Hradec Kralove), 2002, Volume: 45, Issue:2 Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Drug Therapy, Combination; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes	2002
Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication. Archives of toxicology, 2002, Volume: 76, Issue:11 Topics: Acetylcholine; Adenosine; Animals; Cholinesterase Inhibitors; Cholinesterases; Corpus Striatum; Male; Microdialysis; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Parathion; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Sarin	2002
Neuroprotective effects of currently used antidotes in tabun-poisoned rats. Pharmacology & toxicology, 2003, Volume: 92, Issue:6 Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Motor Activity; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar	2003
Protective effect of phenothiazine derivatives against poisoning by the irreversible cholinesterase inhibitor dimethylamidoethoxyphosphoryl cyanide (tabun). Acta pharmacologica et toxicologica, 1953, Volume: 9, Issue:2 Topics: Cholinesterase Inhibitors; Cyanides; Humans; Organophosphate Poisoning; Organophosphates; Phenothiazines; Phosphates	1953
Pyridine-2-aldoxime methiodide in the treatment of sarin and tabun poisoning, with notes on its pharmacology. The Journal of pharmacology and experimental therapeutics, 1957, Volume: 120, Issue:3 Topics: Cholinesterase Inhibitors; Organophosphate Poisoning; Organophosphates; Phosphates; Picolines; Pralidoxime Compounds; Sarin	1957
Canine erythrocyte cholinesterase activity in chronic tabun intoxication. The Journal of pharmacology and experimental therapeutics, 1959, Volume: 126, Issue:2 Topics: Animals; Cholinesterases; Dogs; Drug-Related Side Effects and Adverse Reactions; Erythrocytes; Granuloma; Organophosphate Poisoning; Organophosphates; Phosphates	1959
STUDIES ON REACTIVATION AND AGEING OF BLOOD CHOLINESTERASES OF TABUN INTOXICATED DOGS. Biochemical pharmacology, 1964, Volume: 13 Topics: Aging; Cholinesterases; Dogs; Drug-Related Side Effects and Adverse Reactions; Enzyme Inhibitors; Erythrocytes; Organophosphate Poisoning; Organophosphates; Oximes; Pharmacology; Phosphorus; Poisons; Pralidoxime Compounds; Pyridines; Research; Toxicology	1964
Effect of methoxime combined with anticholinergic, anticonvulsant or anti-HCN drugs in tabun-poisoned mice. Acta medica (Hradec Kralove), 2003, Volume: 46, Issue:3 Topics: Animals; Anticonvulsants; Antidotes; Benactyzine; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Premedication; Pyridostigmine Bromide; Thiosulfates; Trihexyphenidyl	2003
[Effect of acetylcholinesterase reactivator dosage on its effectiveness in the treatment of tabun poisoning in mice]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2004, Volume: 53, Issue:1 Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Mice; Organophosphate Poisoning; Organophosphates; Treatment Outcome	2004
The birth of nerve agent warfare: lessons from Syed Abbas Foroutan. Neurology, 2004, May-11, Volume: 62, Issue:9 Topics: Antidotes; Chemical Warfare; Chemical Warfare Agents; Clinical Protocols; Diagnosis, Differential; Emergency Medical Services; History, 20th Century; Humans; Iran; Iraq; Male; Military Medicine; Military Personnel; Organophosphate Poisoning; Organophosphates; Poisoning; Sarin; Triage; United Nations; Warfare	2004
Anticholinergic drugs--functional antidotes for the treatment of tabun intoxication. Acta medica (Hradec Kralove), 2004, Volume: 47, Issue:1 Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Reactivators; Male; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Rats; Rats, Wistar	2004
The influence of the time of antidotal treatment administration on its effectiveness against tabun-induced poisoning in mice. Acta medica (Hradec Kralove), 2004, Volume: 47, Issue:2 Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Poisoning; Time Factors; Treatment Outcome	2004
Comparison of changes in AChE activity in the brain of the laboratory rat after soman and tabun intoxication. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2004, Volume: 148, Issue:2 Topics: Acetylcholinesterase; Animals; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Diaphragm; Motor Endplate; Organophosphate Poisoning; Organophosphates; Rats; Soman	2004
In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity. Toxicology, 2006, Feb-15, Volume: 219, Issue:1-3 Topics: Acetylcholinesterase; Algorithms; Animals; Cell Line; Cell Survival; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Organophosphate Poisoning; Organophosphates; Oximes; Phosphorylation; Pyridinium Compounds; Soman	2006
The influence of oxime and anticholinergic drug selection on the potency of antidotal treatment to counteract acute toxic effects of tabun in mice. Neurotoxicity research, 2006, Volume: 9, Issue:1 Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Reactivators; Drug Evaluation; Drug Interactions; Lethal Dose 50; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes	2006
Overcoming inhibitions. Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-05, Volume: 103, Issue:36 Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors	2006
A comparison of the efficacy of new asymmetric bispyridinium oximes (K027, K048) with currently available oximes against tabun by in vivo methods. Journal of toxicology and environmental health. Part A, 2006, Volume: 69, Issue:20 Topics: Acetylcholinesterase; Animals; Brain; Chemical Warfare Agents; Diaphragm; Enzyme Activation; Male; Organophosphate Poisoning; Organophosphates; Oximes; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar	2006
Comparison of effects of different antidotes on tabun-induced cognitive impairment in rats using water maze. Acta medica (Hradec Kralove), 2006, Volume: 49, Issue:2 Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Maze Learning; Memory; Organophosphate Poisoning; Organophosphates; Oximes; Rats; Rats, Wistar	2006
Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning. Toxicology, 2006, Nov-10, Volume: 228, Issue:1 Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Antagonism; Drug Therapy, Combination; Erythrocytes; Humans; Lethal Dose 50; Male; Mice; Mice, Inbred BALB C; Organophosphate Poisoning; Organophosphates; Oximes; Poisoning; Pyridinium Compounds	2006
A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats. Journal of enzyme inhibition and medicinal chemistry, 2007, Volume: 22, Issue:3 Topics: Animals; Antidotes; Brain; Butanes; Cholinesterase Reactivators; Drug Evaluation, Preclinical; Male; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Structure-Activity Relationship	2007
The evaluation of the neuroprotective effects of bispyridinium oximes in tabun-poisoned rats. Journal of toxicology and environmental health. Part A, 2007, Volume: 70, Issue:18 Topics: Animals; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Muscarinic Antagonists; Neuroprotective Agents; Neurotoxicity Syndromes; Organophosphate Poisoning; Organophosphates; Oximes; Rats; Rats, Wistar	2007
An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice. Toxicology, 2008, Jan-20, Volume: 243, Issue:3 Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Injections, Intramuscular; Lethal Dose 50; Male; Mice; Molecular Structure; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Species Specificity; Toxicity Tests, Acute; Trimedoxime	2008
A comparison of the potency of newly developed oximes (K074, K075) and currently available oximes (obidoxime, trimedoxime, HI-6) to counteract acute toxic effects of tabun and cyclosarin in mice. Drug and chemical toxicology, 2008, Volume: 31, Issue:1 Topics: Animals; Antidotes; Atropine; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Muscarinic Antagonists; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Trimedoxime	2008
Nerve agents: implications for anesthesia providers. AANA journal, 2008, Volume: 76, Issue:2 Topics: Antidotes; Atropine; Chemical Terrorism; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Decontamination; Humans; Muscarinic Antagonists; Nurse Anesthetists; Nurse's Role; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Sarin; Soman; Time Factors	2008
Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning. Chemico-biological interactions, 2008, Sep-25, Volume: 175, Issue:1-3 Topics: Acetylcholinesterase; Animals; Antidotes; Cholinesterase Inhibitors; Enzyme Reactivators; Male; Mice; Mice, Inbred BALB C; Organophosphate Poisoning; Organophosphates; Oximes; Phosphorylation; Poisoning	2008
Effect of PAM-2 Cl, HI-6, and HGG-12 in poisoning by tabun and its thiocholine-like analog in the rat. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:2 Pt 2 Topics: Animals; Atropine; Choline; Cholinesterase Reactivators; Cholinesterases; Female; Guinea Pigs; Heart; Humans; Lethal Dose 50; Male; Muscle Contraction; Muscle, Smooth; Organophosphate Poisoning; Organophosphates; Oximes; Phrenic Nerve; Pralidoxime Compounds; Pyridinium Compounds; Rats; Thiocholine	1984
PAM-2 Cl, HI-6, and HGG-12 in soman and tabun poisoning. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:2 Pt 2 Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Dogs; Guinea Pigs; Lethal Dose 50; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Soman; Species Specificity	1984
Antidote effect of sodium fluoride against organophosphate poisoning in mice. Life sciences, 1983, Apr-18, Volume: 32, Issue:16 Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Carboxylesterase; Carboxylic Ester Hydrolases; Drug Interactions; Fluorides; Lethal Dose 50; Male; Mice; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Sarin; Sodium Fluoride; Soman	1983
Effect of pyridostigmine pretreatment on cardiorespiratory function in tabun poisoning. Human & experimental toxicology, 1995, Volume: 14, Issue:8 Topics: Animals; Atropine; Blood Pressure; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Guinea Pigs; Heart Rate; Hemodynamics; Injections, Intravenous; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridines; Pyridinium Compounds; Pyridostigmine Bromide; Respiration	1995
Treatment of nerve gas poisoning. The Medical letter on drugs and therapeutics, 1995, May-12, Volume: 37, Issue:948 Topics: Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gases; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Protective Devices; Sarin; Soman	1995
Treatment of tabun poisoned guinea-pigs with atropine, HLö 7 or HI 6: effect on respiratory and circulatory function. Archives of toxicology, 1994, Volume: 68, Issue:4 Topics: Animals; Atropine; Blood Circulation; Cholinesterase Reactivators; Female; Guinea Pigs; Lethal Dose 50; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridines; Pyridinium Compounds; Respiration	1994
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit. Toxicology letters, 1994, Feb-15, Volume: 70, Issue:3 Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms	1994
Efficacy of HLö-7 and pyrimidoxime as antidotes of nerve agent poisoning in mice. Archives of toxicology, 1992, Volume: 66, Issue:3 Topics: Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Imidazoles; Lethal Dose 50; Male; Mice; Neuromuscular Blocking Agents; Organophosphate Poisoning; Organophosphates; Oximes; Pyridines; Pyridinium Compounds; Sarin; Soman	1992
Reduction by pyridostigmine pretreatment of the efficacy of atropine and 2-PAM treatment of sarin and VX poisoning in rodents. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:1 Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin	1992
[Chemical warfare agents]. Ugeskrift for laeger, 1991, Mar-11, Volume: 153, Issue:11 Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Mustard Gas; Organophosphate Poisoning; Organophosphates	1991
HI-6 therapy of soman and tabun poisoning in primates and rodents. Archives of toxicology, 1989, Volume: 63, Issue:2 Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Guinea Pigs; Lethal Dose 50; Macaca mulatta; Male; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Inbred Strains; Respiratory Muscles; Soman	1989
Efficacy of a combination of acetylcholinesterase reactivators, HI-6 and obidoxime, against tabun and soman poisoning of mice. Archives of toxicology, 1987, Volume: 61, Issue:1 Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Soman	1987
[Comparative reactivation efficacy of the oximes HI-6 and HGG-12 in the central nervous system and blood of rats poisoned with nerve gases used in warfare]. Godisnjak Vojnomedicinske akademije = Annual of the Military Medical Academy, 1986, Volume: 28 Topics: Acetylcholinesterase; Animals; Central Nervous System; Chemical Warfare; Cholinesterase Inhibitors; Cholinesterase Reactivators; Gas Poisoning; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Sarin; Soman	1986