Compounds > t 440
Page last updated: 2024-09-05

t 440 and Asthma, Bronchial

t 440 has been researched along with Asthma, Bronchial in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ikezawa, K; Kaminuma, O; Kikkawa, H; Mori, A; Okudaira, H; Suko, M1
Ikezawa, K; Kaminuma, O; Kikkawa, H; Matsubra, S1
Ikezawa, K; Kaminuma, O; Kikkawa, H; Mori, A; Nishizaki, Y; Okudaira, H; Suko, M1
Ikezawa, K; Kaminuma, O; Kikkawa, H; Matsubara, S1

Other Studies

4 other study(ies) available for t 440 and Asthma, Bronchial

ArticleYear
Interleukin-5 production by peripheral blood mononuclear cells of asthmatic patients is suppressed by T-440: relation to phosphodiesterase inhibition.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1

    Topics: Adult; Asthma; Cells, Cultured; Concanavalin A; Cyclic AMP; Humans; Interleukin-2; Interleukin-4; Interleukin-5; Leukocytes, Mononuclear; Naphthalenes; Phosphodiesterase Inhibitors; Pyridones

1996
Inhibitory effect of a novel phosphodiesterase IV inhibitor, T-440, on antigen- and chemical mediator-induced bronchoconstrictions in guinea pigs in vivo.
    Japanese journal of pharmacology, 1996, Volume: 72, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Animals; Asthma; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Antagonists; Injections, Intravenous; Leukotriene D4; Male; Naphthalenes; Phosphodiesterase Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pyridones; Rabbits; Thromboxane A2; Vasoconstrictor Agents

1996
A novel phosphodiesterase inhibitor, T-440: possible management of eosinophilic inflammation by down-regulation of interleukin-5 production.
    International archives of allergy and immunology, 1996, Volume: 111 Suppl 1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Allergens; Animals; Anti-Inflammatory Agents; Asthma; CD4-Positive T-Lymphocytes; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Down-Regulation; Eosinophils; Humans; Hypersensitivity; Interleukin-5; Mites; Naphthalenes; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridones

1996
Effect of T-440, a novel type IV phosphodiesterase inhibitor, on allergen-induced immediate and late asthmatic reaction and leukocyte infiltration into the airways of guinea pigs.
    International archives of allergy and immunology, 1997, Volume: 112, Issue:4

    Topics: Administration, Inhalation; Airway Resistance; Allergens; Animals; Asthma; Chemotaxis, Leukocyte; Dexamethasone; Guinea Pigs; Male; Naphthalenes; Ovalbumin; Phosphodiesterase Inhibitors; Pyridones

1997