t-2 toxin has been researched along with Kashin-Beck Disease in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 23 (71.88) | 24.3611 |
| 2020's | 9 (28.13) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Q; Wang, C; Xiong, Y; Zhang, D; Zhang, R | 1 |
| Cheng, B; Guo, X; Li, P; Liang, C; Ma, M; Wang, B; Wen, Y; Xiao, X; Yang, X; Zhang, F; Zhang, L | 1 |
| Li, B; Li, F; Ma, J; Shao, X; Shi, Y; Sun, M; Zou, N | 1 |
| Luo, J; Luo, K; Sun, L; Wang, M; Wang, Y; Yu, F; Yu, S; Zuo, J | 1 |
| Cheng, B; Cheng, S; Chu, X; Guo, X; Jia, Y; Li, P; Liang, C; Liu, L; Ma, M; Qi, X; Sun, S; Wen, Y; Yao, Y; Ye, J; Yu, W; Zhang, F; Zhang, L | 1 |
| Cao, J; Chen, J; Fang, Q; He, Y; Lammi, MJ; Wang, M; Xue, S; Zhang, M; Zhang, Y | 1 |
| Chen, J; Fang, Q; Feng, Y; Li, Z; Liao, Y; Liu, Y; Wang, H; Wang, M; Wang, W; Zhang, M; Zhang, Y | 1 |
| Chen, J; Guo, X; He, Y; Lin, J; Shi, M; Wang, W; Zhang, Y | 1 |
| Chen, J; Feng, Y; Li, Z; Liao, Y; Liu, Y; Wang, H; Wang, M; Zhang, M; Zhang, Y | 1 |
| Chen, C; Chen, JH; Deng, XH; Fang, Q; Li, SY; Wang, WJ; Wang, ZL; Xue, SH; Yang, HJ; Zhang, M; Zhang, Y; Zhou, XR | 1 |
| Guo, X; Lammi, MJ; Ning, Y; Wang, X; Wu, C; Yang, L; Zhang, J; Zhao, G | 1 |
| Chang, Y; Chen, M; Guo, X; Jin, Z; Lammi, MJ; Sun, Z; Wang, X | 1 |
| Guo, X; Ning, Y; Wang, X; Wang, Y; Yang, L; Zhang, P | 1 |
| Guo, X; Li, X; Wang, X; Xu, C; Yang, L; Zhang, J | 1 |
| Guo, D; Guo, Y; Han, Y; Huang, H; Hussain, S; Lu, S; Min, Z; Sun, J; Sun, M; Xu, P; Zhang, F; Zhao, W; Zhao, Y; Zhong, N | 1 |
| Duan, C; Guo, X; Han, J; He, S; Li, C; Ning, Y; Wu, C | 1 |
| Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z | 1 |
| Chen, C; Chen, J; Li, S; Song, D; Wang, W; Wang, Z; Xue, S; Yang, H; Zhou, X | 1 |
| Gao, F; Kang, P; Li, Y; Liao, J; Pei, F; Yang, X | 1 |
| Kang, P; Pei, F; Shen, B; Song, Y; Yan, D | 1 |
| Pei, F; Song, Y; Yan, D | 1 |
| Bai, Y; Guo, X; Liu, J; Pang, Q; Wang, L; Wu, C; Wu, S; Xu, P | 1 |
| Chen, J; Guan, F; Song, D; Wang, Z; Xue, S; Yang, H; Zhou, X | 1 |
| Dennis, BS; Guo, X; He, S; Hu, S; Jiang, N; Lei, R; Zhang, Q | 1 |
| Deng, J; Duan, L; Huang, H; Kang, P; Pei, FX; Shen, B; Yan, D; Yang, J; Zhou, Z | 1 |
| Duan, L; Kang, P; Pei, F; Shen, B; Yan, D; Yang, J; Zhou, Z | 1 |
| Deng, J; Kang, P; Li, Y; Pei, F; Shen, B; Yan, D; Yang, J; Zhou, Z | 1 |
| Fu, Y; Shi, YX; Wang, LH; Wang, WG | 1 |
| Caterson, B; Chen, JH; Guan, F; Hughes, C; Li, S; Song, D; Wang, W; Wang, ZL; Xue, S; Yang, H; Zhou, W; Zhou, X | 1 |
| Chen, C; Chen, JH; Li, S; Song, D; Wang, W; Wang, ZL; Xue, S; Yang, H; Zhou, X | 1 |
| Cao, J; Caterson, B; Chen, J; Fu, Q; Li, J; Li, S; Liu, F; Liu, J; Lu, M; Luo, M; Wang, J; Zhang, Z | 1 |
| Fu, Y; Li, Q; Meng, FG; Sun, LY; Wang, LH; Zhao, ZJ | 1 |
32 other study(ies) available for t-2 toxin and Kashin-Beck Disease
| Article | Year |
|---|---|
Mechanism of DNA methylation-mediated downregulation of O6-methylguanine-DNA methyltransferase in cartilage injury of Kashin-Beck disease.
Topics: Cartilage, Articular; Chondrocytes; Decitabine; DNA; DNA Methylation; Down-Regulation; Guanine; Humans; Kashin-Beck Disease; RNA, Messenger; Selenium; T-2 Toxin | 2022 |
An integrative analysis of DNA methylation and transcriptome showed the dysfunction of MAPK pathway was involved in the damage of human chondrocyte induced by T-2 toxin.
Topics: Chondrocytes; DNA Methylation; Humans; Kashin-Beck Disease; T-2 Toxin; Transcriptome | 2022 |
MiR-140 is involved in T-2 toxin-induced matrix degradation of articular cartilage.
Topics: Animals; Cartilage, Articular; Kashin-Beck Disease; Matrix Metalloproteinase 13; Mice; MicroRNAs; T-2 Toxin | 2023 |
Selenomethionine Antagonized microRNAs Involved in Apoptosis of Rat Articular Cartilage Induced by T-2 Toxin.
Topics: Animals; Cartilage, Articular; Kashin-Beck Disease; MicroRNAs; Rats; Rats, Sprague-Dawley; Selenomethionine; T-2 Toxin; Tolonium Chloride | 2023 |
WISP1 Is Involved in the Pathogenesis of Kashin-Beck Disease via the Autophagy Pathway.
Topics: Autophagy; Cartilage, Articular; Cell Line; Chondrocytes; Humans; Kashin-Beck Disease; T-2 Toxin; Wnt Signaling Pathway | 2023 |
Expression and localization of the small proteoglycans decorin and biglycan in articular cartilage of Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency.
Topics: Animals; Biglycan; Cartilage, Articular; Child; Chondrocytes; Decorin; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Kashin-Beck Disease; Male; Rats; Selenium; T-2 Toxin | 2019 |
Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease.
Topics: Animals; Cartilage, Articular; Chondrocytes; Disease Models, Animal; HSP47 Heat-Shock Proteins; Kashin-Beck Disease; Rats; Selenium; T-2 Toxin | 2021 |
LncRNA MIAT regulated by selenium and T-2 toxin increases NF-κB-p65 activation, promoting the progress of Kashin-Beck Disease.
Topics: Animals; Disease Models, Animal; Humans; Interleukin-1beta; Kashin-Beck Disease; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; RNA, Long Noncoding; Selenium; T-2 Toxin; Tumor Necrosis Factor-alpha | 2021 |
The decreased expression of integrin αv is involved in T-2 toxin-induced extracellular matrix degradation in chondrocytes.
Topics: Animals; Chondrocytes; Extracellular Matrix; Integrin alphaV; Kashin-Beck Disease; Rats; T-2 Toxin | 2021 |
Increased Chondrocyte Apoptosis in Kashin-Beck Disease and Rats Induced by T-2 Toxin and Selenium Deficiency.
Topics: Adolescent; Animals; Apoptosis; Biomarkers; Cartilage, Articular; Child; Chondrocytes; Female; Humans; Kashin-Beck Disease; Male; Matrilin Proteins; Models, Animal; Random Allocation; Rats; Rats, Sprague-Dawley; Selenium; T-2 Toxin | 2017 |
Gene expression profiles and molecular mechanism of cultured human chondrocytes' exposure to T-2 toxin and deoxynivalenol.
Topics: Adult; Cell Cycle; Cells, Cultured; Chondrocytes; DNA Damage; Extracellular Matrix; Female; Humans; Kashin-Beck Disease; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; T-2 Toxin; Transcriptome; Trichothecenes | 2017 |
Inflammatory cytokine of IL-1β is involved in T-2 toxin-triggered chondrocyte injury and metabolism imbalance by the activation of Wnt/β-catenin signaling.
Topics: Adult; Aggrecans; Animals; Apoptosis; beta Catenin; Chondrocytes; Collagen Type II; Collagenases; Extracellular Matrix; Female; Humans; Interleukin-1beta; Kashin-Beck Disease; Male; Middle Aged; Rats; Rats, Sprague-Dawley; T-2 Toxin; Tissue Inhibitor of Metalloproteinase-1; Transcription, Genetic; Wnt Signaling Pathway | 2017 |
Chondrocytes damage induced by T-2 toxin via Wnt/β-catenin signaling pathway is involved in the pathogenesis of an endemic osteochondropathy, Kashin-Beck disease.
Topics: Adolescent; Adult; beta Catenin; Cartilage, Articular; Case-Control Studies; Cells, Cultured; Child; Chondrocytes; Female; Gene Expression Regulation; Humans; Kashin-Beck Disease; Male; Middle Aged; T-2 Toxin; Wnt Proteins | 2017 |
Expression Profiles of Selenium-Related Genes in Human Chondrocytes Exposed to T-2 Toxin and Deoxynivalenol.
Topics: Chondrocytes; Databases, Genetic; Dose-Response Relationship, Drug; Female; Forkhead Box Protein O1; Gene Expression Profiling; Humans; Kashin-Beck Disease; Male; Middle Aged; Selenium; Signal Transduction; Structure-Activity Relationship; T-2 Toxin; Trichothecenes; Tumor Suppressor Protein p53 | 2019 |
T-2 Toxin Induces Epiphyseal Plate Lesions via Decreased SECISBP2-Mediated Selenoprotein Expression in DA Rats, Exacerbated by Selenium Deficiency.
Topics: Animals; Cartilage, Articular; Disease Models, Animal; Growth Plate; Kashin-Beck Disease; Rats; RNA-Binding Proteins; Selenium; Selenoproteins; T-2 Toxin | 2021 |
[Nano-Se-chondroitin sulfate inhibits T-2 toxin-induced apoptosis of cultured chondrocytes from patients with Kashin-Beck disease].
Topics: Apoptosis; Cells, Cultured; Chondrocytes; Chondroitin Sulfates; Humans; Kashin-Beck Disease; Middle Aged; Nanostructures; T-2 Toxin | 2013 |
An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin.
Topics: Animal Nutritional Physiological Phenomena; Animals; Cartilage, Articular; Chondrocytes; Dietary Proteins; Disease Models, Animal; Female; Growth Plate; Iodine; Kashin-Beck Disease; Male; Malnutrition; Necrosis; Rats; Rats, Sprague-Dawley; Rats, Wistar; Selenium; T-2 Toxin; Thyroxine; Tibia; Triiodothyronine; Weight Gain | 2013 |
Increased levels of IL-6, IL-1β, and TNF-α in Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency.
Topics: Animals; Cartilage, Articular; Child; Disease Models, Animal; Female; Finger Phalanges; Gene Expression; Humans; Interleukin-1beta; Interleukin-6; Kashin-Beck Disease; Knee Joint; Male; Rats, Sprague-Dawley; Selenium; T-2 Toxin; Tumor Necrosis Factor-alpha | 2014 |
MRI evaluation of the effect of Kashin-Beck disease-affected feed and T-2 toxin on the rat knees.
Topics: Animal Feed; Animals; Disease Models, Animal; Kashin-Beck Disease; Knee Joint; Magnetic Resonance Imaging; Rats; Rats, Wistar; T-2 Toxin | 2014 |
Magnetic resonance imaging in the tibial epiphyseal growth plate development of Wistar rat.
Topics: Animals; Bone Development; Case-Control Studies; Chondrocytes; Disease Models, Animal; Epiphyses; Female; Growth Plate; Kashin-Beck Disease; Magnetic Resonance Imaging; Male; Rats; Rats, Wistar; T-2 Toxin; Tibia | 2014 |
Serum levels of M-CSF, RANKL and OPG in rats fed with Kashin-Beck disease-affected diet.
Topics: Animals; Enzyme-Linked Immunosorbent Assay; Female; Kashin-Beck Disease; Macrophage Colony-Stimulating Factor; Male; Osteoprotegerin; RANK Ligand; Rats, Wistar; T-2 Toxin | 2014 |
The role of mitochondria in T-2 toxin-induced human chondrocytes apoptosis.
Topics: Antioxidants; Apoptosis; Cartilage, Articular; Caspase 3; Caspase 9; Cell Survival; Chondrocytes; Citrate (si)-Synthase; Cytochromes c; Electron Transport Complex III; Electron Transport Complex IV; Enzyme Activation; Fusarium; Glutathione; Humans; Kashin-Beck Disease; Middle Aged; Mitochondria; Reactive Oxygen Species; Selenium; T-2 Toxin | 2014 |
T-2 Toxin Alters the Levels of Collagen II and Its Regulatory Enzymes MMPs/TIMP-1 in a Low-Selenium Rat Model of Kashin-Beck Disease.
Topics: Animals; Blotting, Western; Cartilage; Collagen Type II; Disease Models, Animal; Hindlimb; Immunohistochemistry; Kashin-Beck Disease; Male; Matrix Metalloproteinases; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Sternum; T-2 Toxin; Tissue Inhibitor of Metalloproteinase-1 | 2016 |
Prevalence of Selenium, T-2 Toxin, and Deoxynivalenol in Kashin-Beck Disease Areas in Qinghai Province, Northwest China.
Topics: Adolescent; Child; China; Drinking Water; Female; Hair; Humans; Kashin-Beck Disease; Male; Selenium; Soil; T-2 Toxin; Trichothecenes; Triticum | 2016 |
The effect of Kashin-Beck disease-affected feed and T-2 toxin on the bone development of Wistar rats.
Topics: Age Factors; Animal Feed; Animals; Bone Development; Cartilage, Articular; Chondrocytes; Collagen; Disease Models, Animal; Female; Food Contamination; Growth Plate; Humans; Iohexol; Kashin-Beck Disease; Male; Methylene Blue; Necrosis; Rats; Rats, Wistar; T-2 Toxin; Tibia; Weaning; Weight Gain | 2010 |
Serum levels of IL-1β, IL-6 and TNF-α in rats fed with Kashin-Beck disease-affected diet.
Topics: Animals; Biomarkers; Chondrocytes; Diet, Protein-Restricted; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Food Microbiology; Growth Plate; Interleukin-1beta; Interleukin-6; Kashin-Beck Disease; Male; Necrosis; Rats; Rats, Wistar; T-2 Toxin; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
Radiographic findings of Wistar rats fed with T-2 toxin and Kashin-Beck disease-affected diet.
Topics: Animal Feed; Animals; China; Chondrocytes; Disease Models, Animal; Disease Outbreaks; Female; Food Contamination; Growth Plate; Kashin-Beck Disease; Male; Necrosis; Radiography; Rats; Rats, Wistar; Stifle; T-2 Toxin; Tibia | 2011 |
T-2 toxin induces degenerative articular changes in rodents: link to Kaschin-Beck disease.
Topics: Aggrecans; Animals; Cartilage, Articular; Chondrocytes; Disease Models, Animal; Female; Kashin-Beck Disease; Male; Osteoarthritis; Proteoglycans; Rats; Rats, Wistar; T-2 Toxin; Tibia | 2011 |
Histopathology of chondronecrosis development in knee articular cartilage in a rat model of Kashin-Beck disease using T-2 toxin and selenium deficiency conditions.
Topics: Animal Feed; Animals; Body Weight; Cartilage Diseases; Cartilage, Articular; Chondrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione Peroxidase; Growth Plate; Kashin-Beck Disease; Male; Necrosis; Proteoglycans; Rats; Rats, Sprague-Dawley; Selenium; Stifle; T-2 Toxin | 2013 |
Oxidant damage in Kashin-Beck disease and a rat Kashin-Beck disease model by employing T-2 toxin treatment under selenium deficient conditions.
Topics: Animals; Antioxidants; Cartilage; Cartilage, Articular; Catalase; Child; Child, Preschool; Disease Models, Animal; Glutathione Peroxidase; Humans; Kashin-Beck Disease; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Selenium; Superoxide Dismutase; T-2 Toxin; Thiobarbituric Acid Reactive Substances | 2012 |
The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage.
Topics: Aggrecans; Biomarkers; Cells, Cultured; Chondrocytes; Collagen Type II; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Kashin-Beck Disease; Mycotoxins; Selenium; T-2 Toxin; Tissue Engineering; Trichothecenes | 2012 |
T-2 toxin contamination in grains and selenium concentration in drinking water and grains in Kaschin-Beck disease endemic areas of Qinghai Province.
Topics: China; Drinking Water; Edible Grain; Endemic Diseases; Environmental Monitoring; Family Characteristics; Flour; Food Contamination; Food Storage; Health Surveys; Humans; Kashin-Beck Disease; Population Surveillance; Prevalence; Rural Health; Selenium; T-2 Toxin; Triticum; Water Pollution, Chemical; Water Supply | 2012 |